Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ADSS (adenylosuccinate synthase)

Identity

Other aliasADEH
ADSS 2
HGNC (Hugo) ADSS
LocusID (NCBI) 159
Atlas_Id 43109
Location 1q44  [Link to chromosome band 1q44]
Location_base_pair Starts at 244408492 and ends at 244452134 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADSS (1q44) / JMJD1C (10q21.3)ADSS (1q44) / SERTAD4 (1q32.2)GNA12 (7p22.3) / ADSS (1q44)
ADSS 1q44 / SERTAD4 1q32.2GNA12 7p22.3 / ADSS 1q44

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADSS   292
Cards
Entrez_Gene (NCBI)ADSS  159  adenylosuccinate synthase
AliasesADEH; ADSS
GeneCards (Weizmann)ADSS
Ensembl hg19 (Hinxton)ENSG00000035687 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000035687 [Gene_View]  chr1:244408492-244452134 [Contig_View]  ADSS [Vega]
ICGC DataPortalENSG00000035687
TCGA cBioPortalADSS
AceView (NCBI)ADSS
Genatlas (Paris)ADSS
WikiGenes159
SOURCE (Princeton)ADSS
Genetics Home Reference (NIH)ADSS
Genomic and cartography
GoldenPath hg38 (UCSC)ADSS  -     chr1:244408492-244452134 -  1q44   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADSS  -     1q44   [Description]    (hg19-Feb_2009)
EnsemblADSS - 1q44 [CytoView hg19]  ADSS - 1q44 [CytoView hg38]
Mapping of homologs : NCBIADSS [Mapview hg19]  ADSS [Mapview hg38]
OMIM103060   
Gene and transcription
Genbank (Entrez)AK025514 AK303886 AK308749 BC012356 BE538442
RefSeq transcript (Entrez)NM_001126
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADSS
Cluster EST : UnigeneHs.498313 [ NCBI ]
CGAP (NCI)Hs.498313
Alternative Splicing GalleryENSG00000035687
Gene ExpressionADSS [ NCBI-GEO ]   ADSS [ EBI - ARRAY_EXPRESS ]   ADSS [ SEEK ]   ADSS [ MEM ]
Gene Expression Viewer (FireBrowse)ADSS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)159
GTEX Portal (Tissue expression)ADSS
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30520   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30520  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30520
Splice isoforms : SwissVarP30520
PhosPhoSitePlusP30520
Domaine pattern : Prosite (Expaxy)ADENYLOSUCCIN_SYN_1 (PS01266)    ADENYLOSUCCIN_SYN_2 (PS00513)   
Domains : Interpro (EBI)Adenylosuccin_syn_GTP-bd    Adenylosuccin_syn_Lys_AS    Adenylosuccinate_synthetase    AdSS_2_vert    P-loop_NTPase   
Domain families : Pfam (Sanger)Adenylsucc_synt (PF00709)   
Domain families : Pfam (NCBI)pfam00709   
Domain families : Smart (EMBL)Adenylsucc_synt (SM00788)  
Conserved Domain (NCBI)ADSS
DMDM Disease mutations159
Blocks (Seattle)ADSS
PDB (SRS)2V40   
PDB (PDBSum)2V40   
PDB (IMB)2V40   
PDB (RSDB)2V40   
Structural Biology KnowledgeBase2V40   
SCOP (Structural Classification of Proteins)2V40   
CATH (Classification of proteins structures)2V40   
SuperfamilyP30520
Human Protein AtlasENSG00000035687
Peptide AtlasP30520
HPRD00050
IPIIPI00026833   IPI00641992   
Protein Interaction databases
DIP (DOE-UCLA)P30520
IntAct (EBI)P30520
FunCoupENSG00000035687
BioGRIDADSS
STRING (EMBL)ADSS
ZODIACADSS
Ontologies - Pathways
QuickGOP30520
Ontology : AmiGOimmune system process  adenylosuccinate synthase activity  adenylosuccinate synthase activity  adenylosuccinate synthase activity  protein binding  GTP binding  cytoplasm  cytosol  cytosol  plasma membrane  AMP biosynthetic process  AMP biosynthetic process  aspartate metabolic process  purine ribonucleoside monophosphate biosynthetic process  response to purine-containing compound  phosphate ion binding  'de novo' AMP biosynthetic process  'de novo' AMP biosynthetic process  IMP metabolic process  metal ion binding  response to ammonium ion  extracellular exosome  cellular response to electrical stimulus  
Ontology : EGO-EBIimmune system process  adenylosuccinate synthase activity  adenylosuccinate synthase activity  adenylosuccinate synthase activity  protein binding  GTP binding  cytoplasm  cytosol  cytosol  plasma membrane  AMP biosynthetic process  AMP biosynthetic process  aspartate metabolic process  purine ribonucleoside monophosphate biosynthetic process  response to purine-containing compound  phosphate ion binding  'de novo' AMP biosynthetic process  'de novo' AMP biosynthetic process  IMP metabolic process  metal ion binding  response to ammonium ion  extracellular exosome  cellular response to electrical stimulus  
Pathways : KEGGPurine metabolism    Alanine, aspartate and glutamate metabolism   
NDEx NetworkADSS
Atlas of Cancer Signalling NetworkADSS
Wikipedia pathwaysADSS
Orthology - Evolution
OrthoDB159
GeneTree (enSembl)ENSG00000035687
Phylogenetic Trees/Animal Genes : TreeFamADSS
HOVERGENP30520
HOGENOMP30520
Homologs : HomoloGeneADSS
Homology/Alignments : Family Browser (UCSC)ADSS
Gene fusions - Rearrangements
Fusion : MitelmanADSS/SERTAD4 [1q44/1q32.2]  
Fusion : MitelmanGNA12/ADSS [7p22.3/1q44]  [t(1;7)(q44;p22)]  
Fusion: TCGAADSS 1q44 SERTAD4 1q32.2 BRCA
Fusion: TCGAGNA12 7p22.3 ADSS 1q44 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADSS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADSS
dbVarADSS
ClinVarADSS
1000_GenomesADSS 
Exome Variant ServerADSS
ExAC (Exome Aggregation Consortium)ADSS (select the gene name)
Genetic variants : HAPMAP159
Genomic Variants (DGV)ADSS [DGVbeta]
DECIPHERADSS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADSS 
Mutations
ICGC Data PortalADSS 
TCGA Data PortalADSS 
Broad Tumor PortalADSS
OASIS PortalADSS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADSS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADSS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADSS
DgiDB (Drug Gene Interaction Database)ADSS
DoCM (Curated mutations)ADSS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADSS (select a term)
intoGenADSS
Cancer3DADSS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103060   
Orphanet
MedgenADSS
Genetic Testing Registry ADSS
NextProtP30520 [Medical]
TSGene159
GENETestsADSS
Huge Navigator ADSS [HugePedia]
snp3D : Map Gene to Disease159
BioCentury BCIQADSS
ClinGenADSS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD159
Chemical/Pharm GKB GenePA24601
Clinical trialADSS
Miscellaneous
canSAR (ICR)ADSS (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADSS
EVEXADSS
GoPubMedADSS
iHOPADSS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:05:18 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.