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ADSSL1 (adenylosuccinate synthase like 1)

Identity

Alias_symbol (synonym)FLJ38602
Other aliasMPD5
HGNC (Hugo) ADSSL1
LocusID (NCBI) 122622
Atlas_Id 60176
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 104729844 and ends at 104747325 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADSSL1   20093
Cards
Entrez_Gene (NCBI)ADSSL1  122622  adenylosuccinate synthase like 1
AliasesMPD5
GeneCards (Weizmann)ADSSL1
Ensembl hg19 (Hinxton)ENSG00000185100 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185100 [Gene_View]  chr14:104729844-104747325 [Contig_View]  ADSSL1 [Vega]
ICGC DataPortalENSG00000185100
TCGA cBioPortalADSSL1
AceView (NCBI)ADSSL1
Genatlas (Paris)ADSSL1
WikiGenes122622
SOURCE (Princeton)ADSSL1
Genetics Home Reference (NIH)ADSSL1
Genomic and cartography
GoldenPath hg38 (UCSC)ADSSL1  -     chr14:104729844-104747325 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADSSL1  -     14q32.33   [Description]    (hg19-Feb_2009)
EnsemblADSSL1 - 14q32.33 [CytoView hg19]  ADSSL1 - 14q32.33 [CytoView hg38]
Mapping of homologs : NCBIADSSL1 [Mapview hg19]  ADSSL1 [Mapview hg38]
OMIM612498   617030   
Gene and transcription
Genbank (Entrez)AJ573490 AK054648 AK095921 AK096124 AK096720
RefSeq transcript (Entrez)NM_001320424 NM_152328 NM_199165
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ADSSL1
Cluster EST : UnigeneHs.592327 [ NCBI ]
CGAP (NCI)Hs.592327
Alternative Splicing GalleryENSG00000185100
Gene ExpressionADSSL1 [ NCBI-GEO ]   ADSSL1 [ EBI - ARRAY_EXPRESS ]   ADSSL1 [ SEEK ]   ADSSL1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADSSL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)122622
GTEX Portal (Tissue expression)ADSSL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N142   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N142  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N142
Splice isoforms : SwissVarQ8N142
PhosPhoSitePlusQ8N142
Domaine pattern : Prosite (Expaxy)ADENYLOSUCCIN_SYN_1 (PS01266)    ADENYLOSUCCIN_SYN_2 (PS00513)   
Domains : Interpro (EBI)Adenylosuccin_syn_GTP-bd    Adenylosuccin_syn_Lys_AS    Adenylosuccinate_synthetase    AdSS_1_vert    P-loop_NTPase   
Domain families : Pfam (Sanger)Adenylsucc_synt (PF00709)   
Domain families : Pfam (NCBI)pfam00709   
Domain families : Smart (EMBL)Adenylsucc_synt (SM00788)  
Conserved Domain (NCBI)ADSSL1
DMDM Disease mutations122622
Blocks (Seattle)ADSSL1
PDB (SRS)2GJO   
PDB (PDBSum)2GJO   
PDB (IMB)2GJO   
PDB (RSDB)2GJO   
Structural Biology KnowledgeBase2GJO   
SCOP (Structural Classification of Proteins)2GJO   
CATH (Classification of proteins structures)2GJO   
SuperfamilyQ8N142
Human Protein AtlasENSG00000185100
Peptide AtlasQ8N142
HPRD12433
IPIIPI00170914   IPI00167065   IPI01025368   IPI01025473   IPI01025589   
Protein Interaction databases
DIP (DOE-UCLA)Q8N142
IntAct (EBI)Q8N142
FunCoupENSG00000185100
BioGRIDADSSL1
STRING (EMBL)ADSSL1
ZODIACADSSL1
Ontologies - Pathways
QuickGOQ8N142
Ontology : AmiGOimmune system process  GTPase activity  adenylosuccinate synthase activity  adenylosuccinate synthase activity  adenylosuccinate synthase activity  GTP binding  cytoplasm  cytosol  AMP biosynthetic process  aspartate metabolic process  glutamine metabolic process  purine ribonucleoside monophosphate biosynthetic process  response to muscle activity  cellular response to drug  phosphate ion binding  response to starvation  protein homodimerization activity  'de novo' AMP biosynthetic process  'de novo' AMP biosynthetic process  IMP metabolic process  metal ion binding  actin filament binding  cellular response to electrical stimulus  
Ontology : EGO-EBIimmune system process  GTPase activity  adenylosuccinate synthase activity  adenylosuccinate synthase activity  adenylosuccinate synthase activity  GTP binding  cytoplasm  cytosol  AMP biosynthetic process  aspartate metabolic process  glutamine metabolic process  purine ribonucleoside monophosphate biosynthetic process  response to muscle activity  cellular response to drug  phosphate ion binding  response to starvation  protein homodimerization activity  'de novo' AMP biosynthetic process  'de novo' AMP biosynthetic process  IMP metabolic process  metal ion binding  actin filament binding  cellular response to electrical stimulus  
Pathways : KEGGPurine metabolism    Alanine, aspartate and glutamate metabolism   
NDEx NetworkADSSL1
Atlas of Cancer Signalling NetworkADSSL1
Wikipedia pathwaysADSSL1
Orthology - Evolution
OrthoDB122622
GeneTree (enSembl)ENSG00000185100
Phylogenetic Trees/Animal Genes : TreeFamADSSL1
HOVERGENQ8N142
HOGENOMQ8N142
Homologs : HomoloGeneADSSL1
Homology/Alignments : Family Browser (UCSC)ADSSL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADSSL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADSSL1
dbVarADSSL1
ClinVarADSSL1
1000_GenomesADSSL1 
Exome Variant ServerADSSL1
ExAC (Exome Aggregation Consortium)ADSSL1 (select the gene name)
Genetic variants : HAPMAP122622
Genomic Variants (DGV)ADSSL1 [DGVbeta]
DECIPHERADSSL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADSSL1 
Mutations
ICGC Data PortalADSSL1 
TCGA Data PortalADSSL1 
Broad Tumor PortalADSSL1
OASIS PortalADSSL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADSSL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDADSSL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADSSL1
DgiDB (Drug Gene Interaction Database)ADSSL1
DoCM (Curated mutations)ADSSL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADSSL1 (select a term)
intoGenADSSL1
Cancer3DADSSL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612498    617030   
Orphanet
MedgenADSSL1
Genetic Testing Registry ADSSL1
NextProtQ8N142 [Medical]
TSGene122622
GENETestsADSSL1
Target ValidationADSSL1
Huge Navigator ADSSL1 [HugePedia]
snp3D : Map Gene to Disease122622
BioCentury BCIQADSSL1
ClinGenADSSL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD122622
Chemical/Pharm GKB GenePA134974111
Clinical trialADSSL1
Miscellaneous
canSAR (ICR)ADSSL1 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADSSL1
EVEXADSSL1
GoPubMedADSSL1
iHOPADSSL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:00 CEST 2017

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