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AEBP2 (AE binding protein 2)

Identity

Alias_symbol (synonym)MGC17922
Other alias-
HGNC (Hugo) AEBP2
LocusID (NCBI) 121536
Atlas_Id 60178
Location 12p12.3  [Link to chromosome band 12p12]
Location_base_pair Starts at 19439674 and ends at 19522239 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AES (19p13.3) / AEBP2 (12p12.3)AZIN1 (8q22.3) / AEBP2 (12p12.3)ENAH (1q42.12) / AEBP2 (12p12.3)
PLEKHA5 (12p12.3) / AEBP2 (12p12.3)S100A13 (1q21.3) / AEBP2 (12p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AEBP2   24051
Cards
Entrez_Gene (NCBI)AEBP2  121536  AE binding protein 2
Aliases
GeneCards (Weizmann)AEBP2
Ensembl hg19 (Hinxton)ENSG00000139154 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139154 [Gene_View]  chr12:19439674-19522239 [Contig_View]  AEBP2 [Vega]
ICGC DataPortalENSG00000139154
TCGA cBioPortalAEBP2
AceView (NCBI)AEBP2
Genatlas (Paris)AEBP2
WikiGenes121536
SOURCE (Princeton)AEBP2
Genetics Home Reference (NIH)AEBP2
Genomic and cartography
GoldenPath hg38 (UCSC)AEBP2  -     chr12:19439674-19522239 +  12p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AEBP2  -     12p12.3   [Description]    (hg19-Feb_2009)
EnsemblAEBP2 - 12p12.3 [CytoView hg19]  AEBP2 - 12p12.3 [CytoView hg38]
Mapping of homologs : NCBIAEBP2 [Mapview hg19]  AEBP2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA195771 AB209384 AK025788 AK126973 AK131361
RefSeq transcript (Entrez)NM_001114176 NM_001267043 NM_153207
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AEBP2
Cluster EST : UnigeneHs.126497 [ NCBI ]
CGAP (NCI)Hs.126497
Alternative Splicing GalleryENSG00000139154
Gene ExpressionAEBP2 [ NCBI-GEO ]   AEBP2 [ EBI - ARRAY_EXPRESS ]   AEBP2 [ SEEK ]   AEBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)AEBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121536
GTEX Portal (Tissue expression)AEBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZN18   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZN18  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZN18
Splice isoforms : SwissVarQ6ZN18
PhosPhoSitePlusQ6ZN18
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)AEBP2
DMDM Disease mutations121536
Blocks (Seattle)AEBP2
SuperfamilyQ6ZN18
Human Protein AtlasENSG00000139154
Peptide AtlasQ6ZN18
HPRD16477
IPIIPI00796417   IPI00303560   IPI00895818   IPI00903187   IPI01009137   IPI01014276   IPI01013845   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZN18
IntAct (EBI)Q6ZN18
FunCoupENSG00000139154
BioGRIDAEBP2
STRING (EMBL)AEBP2
ZODIACAEBP2
Ontologies - Pathways
QuickGOQ6ZN18
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription corepressor activity  nucleus  nucleoplasm  transcription, DNA-templated  covalent chromatin modification  ESC/E(Z) complex  negative regulation of gene expression, epigenetic  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription corepressor activity  nucleus  nucleoplasm  transcription, DNA-templated  covalent chromatin modification  ESC/E(Z) complex  negative regulation of gene expression, epigenetic  metal ion binding  
NDEx NetworkAEBP2
Atlas of Cancer Signalling NetworkAEBP2
Wikipedia pathwaysAEBP2
Orthology - Evolution
OrthoDB121536
GeneTree (enSembl)ENSG00000139154
Phylogenetic Trees/Animal Genes : TreeFamAEBP2
HOVERGENQ6ZN18
HOGENOMQ6ZN18
Homologs : HomoloGeneAEBP2
Homology/Alignments : Family Browser (UCSC)AEBP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAEBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AEBP2
dbVarAEBP2
ClinVarAEBP2
1000_GenomesAEBP2 
Exome Variant ServerAEBP2
ExAC (Exome Aggregation Consortium)AEBP2 (select the gene name)
Genetic variants : HAPMAP121536
Genomic Variants (DGV)AEBP2 [DGVbeta]
DECIPHERAEBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAEBP2 
Mutations
ICGC Data PortalAEBP2 
TCGA Data PortalAEBP2 
Broad Tumor PortalAEBP2
OASIS PortalAEBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAEBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAEBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AEBP2
DgiDB (Drug Gene Interaction Database)AEBP2
DoCM (Curated mutations)AEBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AEBP2 (select a term)
intoGenAEBP2
Cancer3DAEBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenAEBP2
Genetic Testing Registry AEBP2
NextProtQ6ZN18 [Medical]
TSGene121536
GENETestsAEBP2
Target ValidationAEBP2
Huge Navigator AEBP2 [HugePedia]
snp3D : Map Gene to Disease121536
BioCentury BCIQAEBP2
ClinGenAEBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD121536
Chemical/Pharm GKB GenePA134875401
Clinical trialAEBP2
Miscellaneous
canSAR (ICR)AEBP2 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAEBP2
EVEXAEBP2
GoPubMedAEBP2
iHOPAEBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:37:39 CEST 2017

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