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AEBP2 (AE binding protein 2)

Identity

Alias (NCBI)-
HGNC (Hugo) AEBP2
HGNC Alias symbMGC17922
LocusID (NCBI) 121536
Atlas_Id 60178
Location 12p12.3  [Link to chromosome band 12p12]
Location_base_pair Starts at 19439492 and ends at 19522227 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AES (19p13.3) / AEBP2 (12p12.3)AZIN1 (8q22.3) / AEBP2 (12p12.3)ENAH (1q42.12) / AEBP2 (12p12.3)
PLEKHA5 (12p12.3) / AEBP2 (12p12.3)S100A13 (1q21.3) / AEBP2 (12p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AEBP2   24051
Cards
Entrez_Gene (NCBI)AEBP2    AE binding protein 2
Aliases
GeneCards (Weizmann)AEBP2
Ensembl hg19 (Hinxton)ENSG00000139154 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139154 [Gene_View]  ENSG00000139154 [Sequence]  chr12:19439492-19522227 [Contig_View]  AEBP2 [Vega]
ICGC DataPortalENSG00000139154
TCGA cBioPortalAEBP2
AceView (NCBI)AEBP2
Genatlas (Paris)AEBP2
SOURCE (Princeton)AEBP2
Genetics Home Reference (NIH)AEBP2
Genomic and cartography
GoldenPath hg38 (UCSC)AEBP2  -     chr12:19439492-19522227 +  12p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AEBP2  -     12p12.3   [Description]    (hg19-Feb_2009)
GoldenPathAEBP2 - 12p12.3 [CytoView hg19]  AEBP2 - 12p12.3 [CytoView hg38]
ImmunoBaseENSG00000139154
Genome Data Viewer NCBIAEBP2 [Mapview hg19]  
OMIM617934   
Gene and transcription
Genbank (Entrez)AA195771 AB209384 AK025788 AK126973 AK131361
RefSeq transcript (Entrez)NM_001114176 NM_001267043 NM_001363736 NM_153207
Consensus coding sequences : CCDS (NCBI)AEBP2
Gene ExpressionAEBP2 [ NCBI-GEO ]   AEBP2 [ EBI - ARRAY_EXPRESS ]   AEBP2 [ SEEK ]   AEBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)AEBP2 [ Firebrowse - Broad ]
GenevisibleExpression of AEBP2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121536
GTEX Portal (Tissue expression)AEBP2
Human Protein AtlasENSG00000139154-AEBP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZN18   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZN18  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZN18
PhosPhoSitePlusQ6ZN18
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)AEBP2
PDB (RSDB)5WAI    5Y0U    5Y1U    6C23    6C24   
PDB Europe5WAI    5Y0U    5Y1U    6C23    6C24   
PDB (PDBSum)5WAI    5Y0U    5Y1U    6C23    6C24   
PDB (IMB)5WAI    5Y0U    5Y1U    6C23    6C24   
Structural Biology KnowledgeBase5WAI    5Y0U    5Y1U    6C23    6C24   
SCOP (Structural Classification of Proteins)5WAI    5Y0U    5Y1U    6C23    6C24   
CATH (Classification of proteins structures)5WAI    5Y0U    5Y1U    6C23    6C24   
SuperfamilyQ6ZN18
AlphaFold pdb e-kbQ6ZN18   
Human Protein Atlas [tissue]ENSG00000139154-AEBP2 [tissue]
HPRD16477
Protein Interaction databases
DIP (DOE-UCLA)Q6ZN18
IntAct (EBI)Q6ZN18
BioGRIDAEBP2
STRING (EMBL)AEBP2
ZODIACAEBP2
Ontologies - Pathways
QuickGOQ6ZN18
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA binding  nucleoplasm  nucleoplasm  chromatin organization  regulation of transcription by RNA polymerase II  ESC/E(Z) complex  ESC/E(Z) complex  negative regulation of gene expression, epigenetic  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA binding  nucleoplasm  nucleoplasm  chromatin organization  regulation of transcription by RNA polymerase II  ESC/E(Z) complex  ESC/E(Z) complex  negative regulation of gene expression, epigenetic  metal ion binding  
NDEx NetworkAEBP2
Atlas of Cancer Signalling NetworkAEBP2
Wikipedia pathwaysAEBP2
Orthology - Evolution
OrthoDB121536
GeneTree (enSembl)ENSG00000139154
Phylogenetic Trees/Animal Genes : TreeFamAEBP2
Homologs : HomoloGeneAEBP2
Homology/Alignments : Family Browser (UCSC)AEBP2
Gene fusions - Rearrangements
Fusion : QuiverAEBP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAEBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AEBP2
dbVarAEBP2
ClinVarAEBP2
MonarchAEBP2
1000_GenomesAEBP2 
Exome Variant ServerAEBP2
GNOMAD BrowserENSG00000139154
Varsome BrowserAEBP2
ACMGAEBP2 variants
VarityQ6ZN18
Genomic Variants (DGV)AEBP2 [DGVbeta]
DECIPHERAEBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAEBP2 
Mutations
ICGC Data PortalAEBP2 
TCGA Data PortalAEBP2 
Broad Tumor PortalAEBP2
OASIS PortalAEBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAEBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAEBP2
Mutations and Diseases : HGMDAEBP2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAEBP2
DgiDB (Drug Gene Interaction Database)AEBP2
DoCM (Curated mutations)AEBP2
CIViC (Clinical Interpretations of Variants in Cancer)AEBP2
Cancer3DAEBP2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617934   
Orphanet
DisGeNETAEBP2
MedgenAEBP2
Genetic Testing Registry AEBP2
NextProtQ6ZN18 [Medical]
GENETestsAEBP2
Target ValidationAEBP2
Huge Navigator AEBP2 [HugePedia]
ClinGenAEBP2
Clinical trials, drugs, therapy
MyCancerGenomeAEBP2
Protein Interactions : CTDAEBP2
Pharm GKB GenePA134875401
PharosQ6ZN18
Clinical trialAEBP2
Miscellaneous
canSAR (ICR)AEBP2
HarmonizomeAEBP2
DataMed IndexAEBP2
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAEBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:41:39 CEST 2021

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