AEN (apoptosis enhancing nuclease)

2012-12-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
ISG20L1,pp12744

Other Information

Locus ID:

NCBI: 64782
MIM: 610177
HGNC: 25722
Ensembl: ENSG00000181026

Variants:

dbSNP: 64782
ClinVar: 64782
TCGA: ENSG00000181026
COSMIC: AEN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181026ENST00000332810Q8WTP8
ENSG00000181026ENST00000559528H0YMJ6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

References

Pubmed IDYearTitleCitations
182641332008p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis.22
204299332010ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy.21

Citation

Dessen P

AEN (apoptosis enhancing nuclease)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53064/aen