Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AFAP1L1 (actin filament associated protein 1 like 1)

Identity

Alias_namesactin filament associated protein 1-like 1
Alias_symbol (synonym)FLJ36748
Other alias-
HGNC (Hugo) AFAP1L1
LocusID (NCBI) 134265
Atlas_Id 52489
Location 5q32  [Link to chromosome band 5q32]
Location_base_pair Starts at 148651401 and ends at 148721367 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AFAP1L1 (5q32) / USP47 (11p15.3)APLP2 (11q24.3) / AFAP1L1 (5q32)LAPTM5 (1p35.2) / AFAP1L1 (5q32)
LRRC75A-AS1 (17p11.2) / AFAP1L1 (5q32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AFAP1L1   26714
Cards
Entrez_Gene (NCBI)AFAP1L1  134265  actin filament associated protein 1 like 1
Aliases
GeneCards (Weizmann)AFAP1L1
Ensembl hg19 (Hinxton)ENSG00000157510 [Gene_View]  chr5:148651401-148721367 [Contig_View]  AFAP1L1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000157510 [Gene_View]  chr5:148651401-148721367 [Contig_View]  AFAP1L1 [Vega]
ICGC DataPortalENSG00000157510
TCGA cBioPortalAFAP1L1
AceView (NCBI)AFAP1L1
Genatlas (Paris)AFAP1L1
WikiGenes134265
SOURCE (Princeton)AFAP1L1
Genetics Home Reference (NIH)AFAP1L1
Genomic and cartography
GoldenPath hg19 (UCSC)AFAP1L1  -     chr5:148651401-148721367 +  5q32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AFAP1L1  -     5q32   [Description]    (hg38-Dec_2013)
EnsemblAFAP1L1 - 5q32 [CytoView hg19]  AFAP1L1 - 5q32 [CytoView hg38]
Mapping of homologs : NCBIAFAP1L1 [Mapview hg19]  AFAP1L1 [Mapview hg38]
OMIM614410   
Gene and transcription
Genbank (Entrez)AK074185 AK094067 AK095980 BC040723 BC125093
RefSeq transcript (Entrez)NM_001146337 NM_152406
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_029289 NW_004929324
Consensus coding sequences : CCDS (NCBI)AFAP1L1
Cluster EST : UnigeneHs.483793 [ NCBI ]
CGAP (NCI)Hs.483793
Alternative Splicing GalleryENSG00000157510
Gene ExpressionAFAP1L1 [ NCBI-GEO ]   AFAP1L1 [ EBI - ARRAY_EXPRESS ]   AFAP1L1 [ SEEK ]   AFAP1L1 [ MEM ]
Gene Expression Viewer (FireBrowse)AFAP1L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)134265
GTEX Portal (Tissue expression)AFAP1L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TED9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TED9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TED9
Splice isoforms : SwissVarQ8TED9
PhosPhoSitePlusQ8TED9
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)AFAP    AFAP1L1    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)PH (PF00169)   
Domain families : Pfam (NCBI)pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)AFAP1L1
DMDM Disease mutations134265
Blocks (Seattle)AFAP1L1
SuperfamilyQ8TED9
Human Protein AtlasENSG00000157510
Peptide AtlasQ8TED9
HPRD16943
IPIIPI00163565   IPI00854646   IPI00383447   IPI00854594   
Protein Interaction databases
DIP (DOE-UCLA)Q8TED9
IntAct (EBI)Q8TED9
FunCoupENSG00000157510
BioGRIDAFAP1L1
STRING (EMBL)AFAP1L1
ZODIACAFAP1L1
Ontologies - Pathways
QuickGOQ8TED9
Ontology : AmiGOpodosome  protein binding  nucleus  cytoplasm  plasma membrane  cell junction  invadopodium  
Ontology : EGO-EBIpodosome  protein binding  nucleus  cytoplasm  plasma membrane  cell junction  invadopodium  
NDEx NetworkAFAP1L1
Atlas of Cancer Signalling NetworkAFAP1L1
Wikipedia pathwaysAFAP1L1
Orthology - Evolution
OrthoDB134265
GeneTree (enSembl)ENSG00000157510
Phylogenetic Trees/Animal Genes : TreeFamAFAP1L1
HOVERGENQ8TED9
HOGENOMQ8TED9
Homologs : HomoloGeneAFAP1L1
Homology/Alignments : Family Browser (UCSC)AFAP1L1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAFAP1L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AFAP1L1
dbVarAFAP1L1
ClinVarAFAP1L1
1000_GenomesAFAP1L1 
Exome Variant ServerAFAP1L1
ExAC (Exome Aggregation Consortium)AFAP1L1 (select the gene name)
Genetic variants : HAPMAP134265
Genomic Variants (DGV)AFAP1L1 [DGVbeta]
DECIPHER (Syndromes)5:148651401-148721367  ENSG00000157510
CONAN: Copy Number AnalysisAFAP1L1 
Mutations
ICGC Data PortalAFAP1L1 
TCGA Data PortalAFAP1L1 
Broad Tumor PortalAFAP1L1
OASIS PortalAFAP1L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAFAP1L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAFAP1L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AFAP1L1
DgiDB (Drug Gene Interaction Database)AFAP1L1
DoCM (Curated mutations)AFAP1L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AFAP1L1 (select a term)
intoGenAFAP1L1
Cancer3DAFAP1L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614410   
Orphanet
MedgenAFAP1L1
Genetic Testing Registry AFAP1L1
NextProtQ8TED9 [Medical]
TSGene134265
GENETestsAFAP1L1
Huge Navigator AFAP1L1 [HugePedia]
snp3D : Map Gene to Disease134265
BioCentury BCIQAFAP1L1
ClinGenAFAP1L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD134265
Chemical/Pharm GKB GenePA162375772
Clinical trialAFAP1L1
Miscellaneous
canSAR (ICR)AFAP1L1 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAFAP1L1
EVEXAFAP1L1
GoPubMedAFAP1L1
iHOPAFAP1L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:55:11 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.