AFMID (arylformamidase)

2018-07-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
FKF,KF,KFA
FUSION GENES

Other Information

Locus ID:

NCBI: 125061
HGNC: 20910
Ensembl: ENSG00000183077

Variants:

dbSNP: 125061
ClinVar: 125061
TCGA: ENSG00000183077
COSMIC: AFMID

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183077ENST00000327898Q63HM1
ENSG00000183077ENST00000409257Q63HM1
ENSG00000183077ENST00000586542K7EMM5
ENSG00000183077ENST00000586731K7ELV9
ENSG00000183077ENST00000588199K7EK09
ENSG00000183077ENST00000588800K7EIX3
ENSG00000183077ENST00000589107K7EQK5
ENSG00000183077ENST00000589256W4VSQ7
ENSG00000183077ENST00000591256K7EMI4
ENSG00000183077ENST00000591952K7EPF8

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Tryptophan metabolismKEGGko00380
Glyoxylate and dicarboxylate metabolismKEGGko00630
Tryptophan metabolismKEGGhsa00380
Glyoxylate and dicarboxylate metabolismKEGGhsa00630
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Tryptophan catabolismREACTOMER-HSA-71240
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolismREACTOMER-HSA-6788656

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
294494092018A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma.3

Citation

Dessen P

AFMID (arylformamidase)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57540/afmid