Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AGA (aspartylglucosaminidase)

Identity

Alias_symbol (synonym)ASRG
HGNC (Hugo) AGA
LocusID (NCBI) 175
Atlas_Id 593
Location 4q34.3  [Link to chromosome band 4q34]
Location_base_pair Starts at 178351929 and ends at 178363657 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CCT4 (2p15) / AGA (4q34.3)COG3 (13q14.13) / AGA (4q34.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGA   318
Cards
Entrez_Gene (NCBI)AGA  175  aspartylglucosaminidase
AliasesAGU; ASRG; GA
GeneCards (Weizmann)AGA
Ensembl hg19 (Hinxton)ENSG00000038002 [Gene_View]  chr4:178351929-178363657 [Contig_View]  AGA [Vega]
Ensembl hg38 (Hinxton)ENSG00000038002 [Gene_View]  chr4:178351929-178363657 [Contig_View]  AGA [Vega]
ICGC DataPortalENSG00000038002
TCGA cBioPortalAGA
AceView (NCBI)AGA
Genatlas (Paris)AGA
WikiGenes175
SOURCE (Princeton)AGA
Genetics Home Reference (NIH)AGA
Genomic and cartography
GoldenPath hg19 (UCSC)AGA  -     chr4:178351929-178363657 -  4q34.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AGA  -     4q34.3   [Description]    (hg38-Dec_2013)
EnsemblAGA - 4q34.3 [CytoView hg19]  AGA - 4q34.3 [CytoView hg38]
Mapping of homologs : NCBIAGA [Mapview hg19]  AGA [Mapview hg38]
OMIM208400   613228   
Gene and transcription
Genbank (Entrez)AA490958 AK303370 AK312982 AW467768 BC012392
RefSeq transcript (Entrez)NM_000027 NM_001171988
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_011845 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)AGA
Cluster EST : UnigeneHs.207776 [ NCBI ]
CGAP (NCI)Hs.207776
Alternative Splicing GalleryENSG00000038002
Gene ExpressionAGA [ NCBI-GEO ]   AGA [ EBI - ARRAY_EXPRESS ]   AGA [ SEEK ]   AGA [ MEM ]
Gene Expression Viewer (FireBrowse)AGA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)175
GTEX Portal (Tissue expression)AGA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20933   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20933  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20933
Splice isoforms : SwissVarP20933
Catalytic activity : Enzyme3.5.1.26 [ Enzyme-Expasy ]   3.5.1.263.5.1.26 [ IntEnz-EBI ]   3.5.1.26 [ BRENDA ]   3.5.1.26 [ KEGG ]   
PhosPhoSitePlusP20933
Domains : Interpro (EBI)Ntn_hydrolases_N    Peptidase_T2   
Domain families : Pfam (Sanger)Asparaginase_2 (PF01112)   
Domain families : Pfam (NCBI)pfam01112   
Conserved Domain (NCBI)AGA
DMDM Disease mutations175
Blocks (Seattle)AGA
PDB (SRS)1APY    1APZ   
PDB (PDBSum)1APY    1APZ   
PDB (IMB)1APY    1APZ   
PDB (RSDB)1APY    1APZ   
Structural Biology KnowledgeBase1APY    1APZ   
SCOP (Structural Classification of Proteins)1APY    1APZ   
CATH (Classification of proteins structures)1APY    1APZ   
SuperfamilyP20933
Human Protein AtlasENSG00000038002
Peptide AtlasP20933
HPRD01949
IPIIPI00026259   IPI00909281   IPI00955394   IPI00966865   
Protein Interaction databases
DIP (DOE-UCLA)P20933
IntAct (EBI)P20933
FunCoupENSG00000038002
BioGRIDAGA
STRING (EMBL)AGA
ZODIACAGA
Ontologies - Pathways
QuickGOP20933
Ontology : AmiGON4-(beta-N-acetylglucosaminyl)-L-asparaginase activity  N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity  extracellular space  lysosome  endoplasmic reticulum  proteolysis  protein deglycosylation  protein deglycosylation  peptidase activity  protein self-association  protein maturation  extracellular exosome  
Ontology : EGO-EBIN4-(beta-N-acetylglucosaminyl)-L-asparaginase activity  N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity  extracellular space  lysosome  endoplasmic reticulum  proteolysis  protein deglycosylation  protein deglycosylation  peptidase activity  protein self-association  protein maturation  extracellular exosome  
Pathways : KEGGOther glycan degradation    Lysosome   
NDEx NetworkAGA
Atlas of Cancer Signalling NetworkAGA
Wikipedia pathwaysAGA
Orthology - Evolution
OrthoDB175
GeneTree (enSembl)ENSG00000038002
Phylogenetic Trees/Animal Genes : TreeFamAGA
HOVERGENP20933
HOGENOMP20933
Homologs : HomoloGeneAGA
Homology/Alignments : Family Browser (UCSC)AGA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGA
dbVarAGA
ClinVarAGA
1000_GenomesAGA 
Exome Variant ServerAGA
ExAC (Exome Aggregation Consortium)AGA (select the gene name)
Genetic variants : HAPMAP175
Genomic Variants (DGV)AGA [DGVbeta]
DECIPHER (Syndromes)4:178351929-178363657  ENSG00000038002
CONAN: Copy Number AnalysisAGA 
Mutations
ICGC Data PortalAGA 
TCGA Data PortalAGA 
Broad Tumor PortalAGA
OASIS PortalAGA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AGA
DgiDB (Drug Gene Interaction Database)AGA
DoCM (Curated mutations)AGA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGA (select a term)
intoGenAGA
Cancer3DAGA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM208400    613228   
Orphanet5   
MedgenAGA
Genetic Testing Registry AGA
NextProtP20933 [Medical]
TSGene175
GENETestsAGA
Huge Navigator AGA [HugePedia]
snp3D : Map Gene to Disease175
BioCentury BCIQAGA
ClinGenAGA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD175
Chemical/Pharm GKB GenePA24615
Clinical trialAGA
Miscellaneous
canSAR (ICR)AGA (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGA
EVEXAGA
GoPubMedAGA
iHOPAGA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:30:26 CET 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.