Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1)

Identity

Alias (NCBI)AGAP-1
CENTG2
GGAP1
cnt-g2
HGNC (Hugo) AGAP1
HGNC Alias symbKIAA1099
GGAP1
HGNC Previous nameCENTG2
HGNC Previous namecentaurin, gamma 2
LocusID (NCBI) 116987
Atlas_Id 60185
Location 2q37.2  [Link to chromosome band 2q37]
Location_base_pair Starts at 235494043 and ends at 236131793 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTB (7p22.1) / AGAP1 (2q37.2)AGAP1 (2q37.2) / AANAT (17q25.1)AGAP1 (2q37.2) / F3 (1p21.3)
AGAP1 (2q37.2) / IGSF21 (1p36.13)AGAP1 (2q37.2) / MYH9 (22q12.3)AGAP1 (2q37.2) / RINT1 (7q22.3)
AGAP1 (2q37.2) / SORBS2 (4q35.1)AGAP1 (2q37.2) / SP140L (2q37.1)AGAP1 (2q37.2) / TRIOBP (22q13.1)
AGAP1 (2q37.2) / UBE2F (2q37.3)AGAP1 (2q37.2) / WDR11 (10q26.12)AGAP1 (2q37.2) / ZC2HC1A (8q21.12)
BPIFB1 (20q11.21) / AGAP1 (2q37.2)SEPT2 (2q37.3) / AGAP1 (2q37.2)SKP1 (5q31.1) / AGAP1 (2q37.2)
TMSB10 (2p11.2) / AGAP1 (2q37.2)AGAP1 RINT1AGAP1 WDR11
AGAP1 FAM164AAGAP1 UBE2FAGAP1 IGSF21
AGAP1 AANATAGAP1 SP140L

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AGAP1   16922
Cards
Entrez_Gene (NCBI)AGAP1    ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AliasesAGAP-1; CENTG2; GGAP1; cnt-g2
GeneCards (Weizmann)AGAP1
Ensembl hg19 (Hinxton)ENSG00000157985 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157985 [Gene_View]  ENSG00000157985 [Sequence]  chr2:235494043-236131793 [Contig_View]  AGAP1 [Vega]
ICGC DataPortalENSG00000157985
TCGA cBioPortalAGAP1
AceView (NCBI)AGAP1
Genatlas (Paris)AGAP1
SOURCE (Princeton)AGAP1
Genetics Home Reference (NIH)AGAP1
Genomic and cartography
GoldenPath hg38 (UCSC)AGAP1  -     chr2:235494043-236131793 +  2q37.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AGAP1  -     2q37.2   [Description]    (hg19-Feb_2009)
GoldenPathAGAP1 - 2q37.2 [CytoView hg19]  AGAP1 - 2q37.2 [CytoView hg38]
ImmunoBaseENSG00000157985
Genome Data Viewer NCBIAGAP1 [Mapview hg19]  
OMIM608651   
Gene and transcription
Genbank (Entrez)AB029022 AF413078 AK001722 AK295520 AK300763
RefSeq transcript (Entrez)NM_001037131 NM_001244888 NM_014914
Consensus coding sequences : CCDS (NCBI)AGAP1
Gene ExpressionAGAP1 [ NCBI-GEO ]   AGAP1 [ EBI - ARRAY_EXPRESS ]   AGAP1 [ SEEK ]   AGAP1 [ MEM ]
Gene Expression Viewer (FireBrowse)AGAP1 [ Firebrowse - Broad ]
GenevisibleExpression of AGAP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116987
GTEX Portal (Tissue expression)AGAP1
Human Protein AtlasENSG00000157985-AGAP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPQ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPQ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPQ3
PhosPhoSitePlusQ9UPQ3
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    ARFGAP (PS50115)    PH_DOMAIN (PS50003)    RAB (PS51419)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf    ARFGAP/RecO    ArfGAP_dom    ArfGAP_dom_sf    P-loop_NTPase    PH-like_dom_sf    PH_domain    Small_GTPase   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    ArfGap (PF01412)    Ras (PF00071)   
Domain families : Pfam (NCBI)pfam12796    pfam01412    pfam00071   
Domain families : Smart (EMBL)ANK (SM00248)  ArfGap (SM00105)  PH (SM00233)  
Conserved Domain (NCBI)AGAP1
SuperfamilyQ9UPQ3
AlphaFold pdb e-kbQ9UPQ3   
Human Protein Atlas [tissue]ENSG00000157985-AGAP1 [tissue]
HPRD16359
Protein Interaction databases
DIP (DOE-UCLA)Q9UPQ3
IntAct (EBI)Q9UPQ3
BioGRIDAGAP1
STRING (EMBL)AGAP1
ZODIACAGAP1
Ontologies - Pathways
QuickGOQ9UPQ3
Ontology : AmiGOGTPase activity  GTPase activator activity  protein binding  GTP binding  phospholipid binding  nucleus  cytoplasm  protein transport  metal ion binding  regulation of catalytic activity  
Ontology : EGO-EBIGTPase activity  GTPase activator activity  protein binding  GTP binding  phospholipid binding  nucleus  cytoplasm  protein transport  metal ion binding  regulation of catalytic activity  
NDEx NetworkAGAP1
Atlas of Cancer Signalling NetworkAGAP1
Wikipedia pathwaysAGAP1
Orthology - Evolution
OrthoDB116987
GeneTree (enSembl)ENSG00000157985
Phylogenetic Trees/Animal Genes : TreeFamAGAP1
Homologs : HomoloGeneAGAP1
Homology/Alignments : Family Browser (UCSC)AGAP1
Gene fusions - Rearrangements
Fusion : QuiverAGAP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGAP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGAP1
dbVarAGAP1
ClinVarAGAP1
MonarchAGAP1
1000_GenomesAGAP1 
Exome Variant ServerAGAP1
GNOMAD BrowserENSG00000157985
Varsome BrowserAGAP1
ACMGAGAP1 variants
VarityQ9UPQ3
Genomic Variants (DGV)AGAP1 [DGVbeta]
DECIPHERAGAP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAGAP1 
Mutations
ICGC Data PortalAGAP1 
TCGA Data PortalAGAP1 
Broad Tumor PortalAGAP1
OASIS PortalAGAP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGAP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAGAP1
Mutations and Diseases : HGMDAGAP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAGAP1
DgiDB (Drug Gene Interaction Database)AGAP1
DoCM (Curated mutations)AGAP1
CIViC (Clinical Interpretations of Variants in Cancer)AGAP1
Cancer3DAGAP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608651   
Orphanet
DisGeNETAGAP1
MedgenAGAP1
Genetic Testing Registry AGAP1
NextProtQ9UPQ3 [Medical]
GENETestsAGAP1
Target ValidationAGAP1
Huge Navigator AGAP1 [HugePedia]
ClinGenAGAP1
Clinical trials, drugs, therapy
MyCancerGenomeAGAP1
Protein Interactions : CTDAGAP1
Pharm GKB GenePA26412
PharosQ9UPQ3
Clinical trialAGAP1
Miscellaneous
canSAR (ICR)AGAP1
HarmonizomeAGAP1
DataMed IndexAGAP1
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAGAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:41:41 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.