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AGAP4 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 4)

Identity

Alias_namesCTGLF1
AGAP8
CTGLF5
centaurin, gamma-like family, member 1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
centaurin, gamma-like family, member 5
Alias_symbol (synonym)Em:AC012044.1
MRIP2
Other aliasAGAP-4
AGAP-8
HGNC (Hugo) AGAP4
LocusID (NCBI) 119016
Atlas_Id 60188
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 45825592 and ends at 45847473 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGAP4   23459
Cards
Entrez_Gene (NCBI)AGAP4  119016  ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
AliasesAGAP-4; AGAP-8; AGAP8; CTGLF1; 
CTGLF5; MRIP2
GeneCards (Weizmann)AGAP4
Ensembl hg19 (Hinxton)ENSG00000188234 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188234 [Gene_View]  chr10:45825592-45847473 [Contig_View]  AGAP4 [Vega]
ICGC DataPortalENSG00000188234
TCGA cBioPortalAGAP4
AceView (NCBI)AGAP4
Genatlas (Paris)AGAP4
WikiGenes119016
SOURCE (Princeton)AGAP4
Genetics Home Reference (NIH)AGAP4
Genomic and cartography
GoldenPath hg38 (UCSC)AGAP4  -     chr10:45825592-45847473 -  10q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AGAP4  -     10q11.22   [Description]    (hg19-Feb_2009)
EnsemblAGAP4 - 10q11.22 [CytoView hg19]  AGAP4 - 10q11.22 [CytoView hg38]
Mapping of homologs : NCBIAGAP4 [Mapview hg19]  AGAP4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF411132 AK096107 AW089174 BC048341 BC062366
RefSeq transcript (Entrez)NM_001077686 NM_001276343 NM_001276344 NM_001291379 NM_133446
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AGAP4
Cluster EST : UnigeneHs.656384 [ NCBI ]
CGAP (NCI)Hs.656384
Alternative Splicing GalleryENSG00000188234
Gene ExpressionAGAP4 [ NCBI-GEO ]   AGAP4 [ EBI - ARRAY_EXPRESS ]   AGAP4 [ SEEK ]   AGAP4 [ MEM ]
Gene Expression Viewer (FireBrowse)AGAP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)119016
GTEX Portal (Tissue expression)AGAP4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96P64   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96P64  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96P64
Splice isoforms : SwissVarQ96P64
PhosPhoSitePlusQ96P64
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    ARFGAP (PS50115)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    ArfGAP    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    ArfGap (PF01412)   
Domain families : Pfam (NCBI)pfam12796    pfam01412   
Domain families : Smart (EMBL)ANK (SM00248)  ArfGap (SM00105)  PH (SM00233)  
Conserved Domain (NCBI)AGAP4
DMDM Disease mutations119016
Blocks (Seattle)AGAP4
SuperfamilyQ96P64
Human Protein AtlasENSG00000188234
Peptide AtlasQ96P64
HPRD16771
IPIIPI00454973   IPI00939613   IPI00968080   
Protein Interaction databases
DIP (DOE-UCLA)Q96P64
IntAct (EBI)Q96P64
FunCoupENSG00000188234
BioGRIDAGAP4
STRING (EMBL)AGAP4
ZODIACAGAP4
Ontologies - Pathways
QuickGOQ96P64
Ontology : AmiGOGTPase activator activity  positive regulation of GTPase activity  metal ion binding  
Ontology : EGO-EBIGTPase activator activity  positive regulation of GTPase activity  metal ion binding  
NDEx NetworkAGAP4
Atlas of Cancer Signalling NetworkAGAP4
Wikipedia pathwaysAGAP4
Orthology - Evolution
OrthoDB119016
GeneTree (enSembl)ENSG00000188234
Phylogenetic Trees/Animal Genes : TreeFamAGAP4
HOVERGENQ96P64
HOGENOMQ96P64
Homologs : HomoloGeneAGAP4
Homology/Alignments : Family Browser (UCSC)AGAP4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGAP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGAP4
dbVarAGAP4
ClinVarAGAP4
1000_GenomesAGAP4 
Exome Variant ServerAGAP4
ExAC (Exome Aggregation Consortium)AGAP4 (select the gene name)
Genetic variants : HAPMAP119016
Genomic Variants (DGV)AGAP4 [DGVbeta]
DECIPHERAGAP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAGAP4 
Mutations
ICGC Data PortalAGAP4 
TCGA Data PortalAGAP4 
Broad Tumor PortalAGAP4
OASIS PortalAGAP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGAP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGAP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AGAP4
DgiDB (Drug Gene Interaction Database)AGAP4
DoCM (Curated mutations)AGAP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGAP4 (select a term)
intoGenAGAP4
Cancer3DAGAP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenAGAP4
Genetic Testing Registry AGAP4
NextProtQ96P64 [Medical]
TSGene119016
GENETestsAGAP4
Target ValidationAGAP4
Huge Navigator AGAP4 [HugePedia]
snp3D : Map Gene to Disease119016
BioCentury BCIQAGAP4
ClinGenAGAP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD119016
Chemical/Pharm GKB GenePA164715122
Clinical trialAGAP4
Miscellaneous
canSAR (ICR)AGAP4 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGAP4
EVEXAGAP4
GoPubMedAGAP4
iHOPAGAP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:37:41 CEST 2017

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