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AGBL4 (ATP/GTP binding protein like 4)

Identity

Alias_symbol (synonym)FLJ14442
CCP6
Other alias
HGNC (Hugo) AGBL4
LocusID (NCBI) 84871
Atlas_Id 54111
Location 1p33  [Link to chromosome band 1p33]
Location_base_pair Starts at 48532855 and ends at 50023954 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGBL4 (1p33) / AGBL4 (1p33)AGBL4 (1p33) / DNAH17 (17q25.3)AGBL4 (1p33) / DTL (1q32.3)
AGBL4 (1p33) / ELAVL4 (1p33)AGBL4 (1p33) / FAF1 (1p32.3)AGBL4 (1p33) / HNRNPC (14q11.2)
AGBL4 (1p33) / NTRK2 (9q21.33)AGBL4 (1p33) / SPAG6 (10p12.2)C11orf58 (11p15.1) / AGBL4 (1p33)
DTL (1q32.3) / AGBL4 (1p33)FAF1 (1p32.3) / AGBL4 (1p33)FUT8 (14q23.3) / AGBL4 (1p33)
HIRA (22q11.21) / AGBL4 (1p33)PTGFRN (1p13.1) / AGBL4 (1p33)STRADA (17q23.3) / AGBL4 (1p33)
ZNF267 (16p11.2) / AGBL4 (1p33)AGBL4 1p33 / DTL 1q32.3AGBL4 1p33 / FAF1 1p32.3
DTL 1q32.3 / AGBL4 1p33FUT8 14q23.3 / AGBL4 1p33PTGFRN 1p13.1 / AGBL4 1p33
ZNF267 16p11.2 / AGBL4 1p33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGBL4   25892
Cards
Entrez_Gene (NCBI)AGBL4  84871  ATP/GTP binding protein like 4
AliasesCCP6
GeneCards (Weizmann)AGBL4
Ensembl hg19 (Hinxton)ENSG00000186094 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186094 [Gene_View]  chr1:48532855-50023954 [Contig_View]  AGBL4 [Vega]
ICGC DataPortalENSG00000186094
TCGA cBioPortalAGBL4
AceView (NCBI)AGBL4
Genatlas (Paris)AGBL4
WikiGenes84871
SOURCE (Princeton)AGBL4
Genetics Home Reference (NIH)AGBL4
Genomic and cartography
GoldenPath hg38 (UCSC)AGBL4  -     chr1:48532855-50023954 -  1p33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AGBL4  -     1p33   [Description]    (hg19-Feb_2009)
EnsemblAGBL4 - 1p33 [CytoView hg19]  AGBL4 - 1p33 [CytoView hg38]
Mapping of homologs : NCBIAGBL4 [Mapview hg19]  AGBL4 [Mapview hg38]
OMIM616476   
Gene and transcription
Genbank (Entrez)AF075049 AK027348 AK094826 AK294394 AK294633
RefSeq transcript (Entrez)NM_001323573 NM_001323574 NM_001323575 NM_032785
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AGBL4
Cluster EST : UnigeneHs.679809 [ NCBI ]
CGAP (NCI)Hs.679809
Alternative Splicing GalleryENSG00000186094
Gene ExpressionAGBL4 [ NCBI-GEO ]   AGBL4 [ EBI - ARRAY_EXPRESS ]   AGBL4 [ SEEK ]   AGBL4 [ MEM ]
Gene Expression Viewer (FireBrowse)AGBL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84871
GTEX Portal (Tissue expression)AGBL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VU57   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VU57  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VU57
Splice isoforms : SwissVarQ5VU57
Catalytic activity : Enzyme3.4.17.- [ Enzyme-Expasy ]   3.4.17.-3.4.17.- [ IntEnz-EBI ]   3.4.17.- [ BRENDA ]   3.4.17.- [ KEGG ]   
PhosPhoSitePlusQ5VU57
Domains : Interpro (EBI)Peptidase_M14   
Domain families : Pfam (Sanger)Peptidase_M14 (PF00246)   
Domain families : Pfam (NCBI)pfam00246   
Domain families : Smart (EMBL)Zn_pept (SM00631)  
Conserved Domain (NCBI)AGBL4
DMDM Disease mutations84871
Blocks (Seattle)AGBL4
SuperfamilyQ5VU57
Human Protein AtlasENSG00000186094
Peptide AtlasQ5VU57
HPRD07487
IPIIPI01013035   IPI00973592   IPI00064477   IPI01012945   IPI00910518   IPI00477383   IPI00647826   
Protein Interaction databases
DIP (DOE-UCLA)Q5VU57
IntAct (EBI)Q5VU57
FunCoupENSG00000186094
BioGRIDAGBL4
STRING (EMBL)AGBL4
ZODIACAGBL4
Ontologies - Pathways
QuickGOQ5VU57
Ontology : AmiGOmetallocarboxypeptidase activity  Golgi apparatus  centriole  cytosol  proteolysis  zinc ion binding  tubulin binding  protein deglutamylation  C-terminal protein deglutamylation  protein side chain deglutamylation  ciliary basal body  defense response to virus  
Ontology : EGO-EBImetallocarboxypeptidase activity  Golgi apparatus  centriole  cytosol  proteolysis  zinc ion binding  tubulin binding  protein deglutamylation  C-terminal protein deglutamylation  protein side chain deglutamylation  ciliary basal body  defense response to virus  
NDEx NetworkAGBL4
Atlas of Cancer Signalling NetworkAGBL4
Wikipedia pathwaysAGBL4
Orthology - Evolution
OrthoDB84871
GeneTree (enSembl)ENSG00000186094
Phylogenetic Trees/Animal Genes : TreeFamAGBL4
HOVERGENQ5VU57
HOGENOMQ5VU57
Homologs : HomoloGeneAGBL4
Homology/Alignments : Family Browser (UCSC)AGBL4
Gene fusions - Rearrangements
Fusion : MitelmanAGBL4/DTL [1p33/1q32.3]  
Fusion : MitelmanAGBL4/FAF1 [1p33/1p32.3]  [t(1;1)(p32;p33)]  
Fusion : MitelmanAGBL4/NTRK2 [1p33/9q21.33]  [t(1;9)(p33;q21)]  
Fusion : MitelmanDTL/AGBL4 [1q32.3/1p33]  [t(1;1)(p33;q32)]  
Fusion : MitelmanFUT8/AGBL4 [14q23.3/1p33]  [t(1;14)(p33;q23)]  
Fusion : MitelmanINADL/AGBL4 [1p31.3/1p33]  [t(1;1)(p31;p33)]  
Fusion : MitelmanPTGFRN/AGBL4 [1p13.1/1p33]  [t(1;1)(p13;p33)]  
Fusion : MitelmanZNF267/AGBL4 [16p11.2/1p33]  [t(1;16)(p33;p11)]  
Fusion: TCGAAGBL4 1p33 DTL 1q32.3 LUAD
Fusion: TCGAAGBL4 1p33 FAF1 1p32.3 BRCA PRAD
Fusion: TCGADTL 1q32.3 AGBL4 1p33 LUAD
Fusion: TCGAFUT8 14q23.3 AGBL4 1p33 BRCA
Fusion: TCGAPTGFRN 1p13.1 AGBL4 1p33 BRCA
Fusion: TCGAZNF267 16p11.2 AGBL4 1p33 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGBL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGBL4
dbVarAGBL4
ClinVarAGBL4
1000_GenomesAGBL4 
Exome Variant ServerAGBL4
ExAC (Exome Aggregation Consortium)AGBL4 (select the gene name)
Genetic variants : HAPMAP84871
Genomic Variants (DGV)AGBL4 [DGVbeta]
DECIPHERAGBL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAGBL4 
Mutations
ICGC Data PortalAGBL4 
TCGA Data PortalAGBL4 
Broad Tumor PortalAGBL4
OASIS PortalAGBL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGBL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGBL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AGBL4
DgiDB (Drug Gene Interaction Database)AGBL4
DoCM (Curated mutations)AGBL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGBL4 (select a term)
intoGenAGBL4
Cancer3DAGBL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616476   
Orphanet
MedgenAGBL4
Genetic Testing Registry AGBL4
NextProtQ5VU57 [Medical]
TSGene84871
GENETestsAGBL4
Huge Navigator AGBL4 [HugePedia]
snp3D : Map Gene to Disease84871
BioCentury BCIQAGBL4
ClinGenAGBL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84871
Chemical/Pharm GKB GenePA142672636
Clinical trialAGBL4
Miscellaneous
canSAR (ICR)AGBL4 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGBL4
EVEXAGBL4
GoPubMedAGBL4
iHOPAGBL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:05:21 CEST 2017

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