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AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1)

Identity

Alias_names1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
Alias_symbol (synonym)LPAAT-alpha
Other alias1-AGPAT1
G15
LPAATA
HGNC (Hugo) AGPAT1
LocusID (NCBI) 10554
Atlas_Id 60203
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 32168206 and ends at 32176139 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGPAT1   324
Cards
Entrez_Gene (NCBI)AGPAT1  10554  1-acylglycerol-3-phosphate O-acyltransferase 1
Aliases1-AGPAT1; G15; LPAAT-alpha; LPAATA
GeneCards (Weizmann)AGPAT1
Ensembl hg19 (Hinxton)ENSG00000204310 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204310 [Gene_View]  chr6:32168206-32176139 [Contig_View]  AGPAT1 [Vega]
ICGC DataPortalENSG00000204310
TCGA cBioPortalAGPAT1
AceView (NCBI)AGPAT1
Genatlas (Paris)AGPAT1
WikiGenes10554
SOURCE (Princeton)AGPAT1
Genetics Home Reference (NIH)AGPAT1
Genomic and cartography
GoldenPath hg38 (UCSC)AGPAT1  -     chr6:32168206-32176139 -  6p21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AGPAT1  -     6p21.32   [Description]    (hg19-Feb_2009)
EnsemblAGPAT1 - 6p21.32 [CytoView hg19]  AGPAT1 - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBIAGPAT1 [Mapview hg19]  AGPAT1 [Mapview hg38]
OMIM603099   
Gene and transcription
Genbank (Entrez)AF007145 AF218034 AI193422 AK056346 AK058025
RefSeq transcript (Entrez)NM_006411 NM_032741
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_113891 NT_167244 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)AGPAT1
Cluster EST : UnigeneHs.409230 [ NCBI ]
CGAP (NCI)Hs.409230
Alternative Splicing GalleryENSG00000204310
Gene ExpressionAGPAT1 [ NCBI-GEO ]   AGPAT1 [ EBI - ARRAY_EXPRESS ]   AGPAT1 [ SEEK ]   AGPAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)AGPAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10554
GTEX Portal (Tissue expression)AGPAT1
Human Protein AtlasENSG00000204310-AGPAT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99943   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99943  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99943
Splice isoforms : SwissVarQ99943
Catalytic activity : Enzyme2.3.1.51 [ Enzyme-Expasy ]   2.3.1.512.3.1.51 [ IntEnz-EBI ]   2.3.1.51 [ BRENDA ]   2.3.1.51 [ KEGG ]   
PhosPhoSitePlusQ99943
Domains : Interpro (EBI)AGP_acyltrans    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)AGPAT1
DMDM Disease mutations10554
Blocks (Seattle)AGPAT1
SuperfamilyQ99943
Human Protein Atlas [tissue]ENSG00000204310-AGPAT1 [tissue]
Peptide AtlasQ99943
HPRD04372
IPIIPI00019141   IPI00902608   IPI01015193   
Protein Interaction databases
DIP (DOE-UCLA)Q99943
IntAct (EBI)Q99943
FunCoupENSG00000204310
BioGRIDAGPAT1
STRING (EMBL)AGPAT1
ZODIACAGPAT1
Ontologies - Pathways
QuickGOQ99943
Ontology : AmiGO###############################################################################################################################################################################################################################################################                              
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                              
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism   
NDEx NetworkAGPAT1
Atlas of Cancer Signalling NetworkAGPAT1
Wikipedia pathwaysAGPAT1
Orthology - Evolution
OrthoDB10554
GeneTree (enSembl)ENSG00000204310
Phylogenetic Trees/Animal Genes : TreeFamAGPAT1
HOVERGENQ99943
HOGENOMQ99943
Homologs : HomoloGeneAGPAT1
Homology/Alignments : Family Browser (UCSC)AGPAT1
Gene fusions - Rearrangements
Fusion : QuiverAGPAT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGPAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGPAT1
dbVarAGPAT1
ClinVarAGPAT1
1000_GenomesAGPAT1 
Exome Variant ServerAGPAT1
ExAC (Exome Aggregation Consortium)ENSG00000204310
GNOMAD BrowserENSG00000204310
Genetic variants : HAPMAP10554
Genomic Variants (DGV)AGPAT1 [DGVbeta]
DECIPHERAGPAT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAGPAT1 
Mutations
ICGC Data PortalAGPAT1 
TCGA Data PortalAGPAT1 
Broad Tumor PortalAGPAT1
OASIS PortalAGPAT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGPAT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGPAT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AGPAT1
DgiDB (Drug Gene Interaction Database)AGPAT1
DoCM (Curated mutations)AGPAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGPAT1 (select a term)
intoGenAGPAT1
Cancer3DAGPAT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603099   
Orphanet
DisGeNETAGPAT1
MedgenAGPAT1
Genetic Testing Registry AGPAT1
NextProtQ99943 [Medical]
TSGene10554
GENETestsAGPAT1
Target ValidationAGPAT1
Huge Navigator AGPAT1 [HugePedia]
snp3D : Map Gene to Disease10554
BioCentury BCIQAGPAT1
ClinGenAGPAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10554
Chemical/Pharm GKB GenePA24621
Clinical trialAGPAT1
Miscellaneous
canSAR (ICR)AGPAT1 (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGPAT1
EVEXAGPAT1
GoPubMedAGPAT1
iHOPAGPAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:10:30 CET 2018

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