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AGPAT3 (1-acylglycerol-3-phosphate O-acyltransferase 3)

Identity

Alias_symbol (synonym)LPAAT-gamma
Other aliasLPAAT-GAMMA1
LPAAT3
HGNC (Hugo) AGPAT3
LocusID (NCBI) 56894
Atlas_Id 60204
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 45345279 and ends at 45407475 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AGPAT3 (21q22.3) / ATP1A4 (1q23.2)AGPAT3 (21q22.3) / KSR1 (17q11.1)AGPAT3 (21q22.3) / PDXK (21q22.3)
LAMA5 (20q13.33) / AGPAT3 (21q22.3)TMOD1 (9q22.33) / AGPAT3 (21q22.3)AGPAT3 PDXK
AGPAT3 KSR1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGPAT3   326
Cards
Entrez_Gene (NCBI)AGPAT3  56894  1-acylglycerol-3-phosphate O-acyltransferase 3
AliasesLPAAT-GAMMA1; LPAAT3
GeneCards (Weizmann)AGPAT3
Ensembl hg19 (Hinxton)ENSG00000160216 [Gene_View]  chr21:45345279-45407475 [Contig_View]  AGPAT3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000160216 [Gene_View]  chr21:45345279-45407475 [Contig_View]  AGPAT3 [Vega]
ICGC DataPortalENSG00000160216
TCGA cBioPortalAGPAT3
AceView (NCBI)AGPAT3
Genatlas (Paris)AGPAT3
WikiGenes56894
SOURCE (Princeton)AGPAT3
Genetics Home Reference (NIH)AGPAT3
Genomic and cartography
GoldenPath hg19 (UCSC)AGPAT3  -     chr21:45345279-45407475 +  21q22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AGPAT3  -     21q22.3   [Description]    (hg38-Dec_2013)
EnsemblAGPAT3 - 21q22.3 [CytoView hg19]  AGPAT3 - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBIAGPAT3 [Mapview hg19]  AGPAT3 [Mapview hg38]
OMIM614794   
Gene and transcription
Genbank (Entrez)AB040138 AF156774 AF156775 AK026135 AK074300
RefSeq transcript (Entrez)NM_001037553 NM_020132
RefSeq genomic (Entrez)NC_000021 NC_018932 NT_011512 NW_004929427
Consensus coding sequences : CCDS (NCBI)AGPAT3
Cluster EST : UnigeneHs.248785 [ NCBI ]
CGAP (NCI)Hs.248785
Alternative Splicing GalleryENSG00000160216
Gene ExpressionAGPAT3 [ NCBI-GEO ]   AGPAT3 [ EBI - ARRAY_EXPRESS ]   AGPAT3 [ SEEK ]   AGPAT3 [ MEM ]
Gene Expression Viewer (FireBrowse)AGPAT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56894
GTEX Portal (Tissue expression)AGPAT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRZ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRZ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRZ7
Splice isoforms : SwissVarQ9NRZ7
Catalytic activity : Enzyme2.3.1.51 [ Enzyme-Expasy ]   2.3.1.512.3.1.51 [ IntEnz-EBI ]   2.3.1.51 [ BRENDA ]   2.3.1.51 [ KEGG ]   
PhosPhoSitePlusQ9NRZ7
Domains : Interpro (EBI)Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)AGPAT3
DMDM Disease mutations56894
Blocks (Seattle)AGPAT3
SuperfamilyQ9NRZ7
Human Protein AtlasENSG00000160216
Peptide AtlasQ9NRZ7
HPRD10637
IPIIPI00217814   IPI00445527   IPI00795305   IPI00383037   IPI00749011   IPI00792264   IPI00942321   IPI00797271   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRZ7
IntAct (EBI)Q9NRZ7
FunCoupENSG00000160216
BioGRIDAGPAT3
STRING (EMBL)AGPAT3
ZODIACAGPAT3
Ontologies - Pathways
QuickGOQ9NRZ7
Ontology : AmiGO1-acylglycerol-3-phosphate O-acyltransferase activity  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  phospholipid metabolic process  phosphatidic acid biosynthetic process  phospholipid biosynthetic process  membrane  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  cellular lipid metabolic process  small molecule metabolic process  glycerophospholipid biosynthetic process  
Ontology : EGO-EBI1-acylglycerol-3-phosphate O-acyltransferase activity  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  phospholipid metabolic process  phosphatidic acid biosynthetic process  phospholipid biosynthetic process  membrane  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  cellular lipid metabolic process  small molecule metabolic process  glycerophospholipid biosynthetic process  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism   
NDEx NetworkAGPAT3
Atlas of Cancer Signalling NetworkAGPAT3
Wikipedia pathwaysAGPAT3
Orthology - Evolution
OrthoDB56894
GeneTree (enSembl)ENSG00000160216
Phylogenetic Trees/Animal Genes : TreeFamAGPAT3
HOVERGENQ9NRZ7
HOGENOMQ9NRZ7
Homologs : HomoloGeneAGPAT3
Homology/Alignments : Family Browser (UCSC)AGPAT3
Gene fusions - Rearrangements
Fusion: TCGAAGPAT3 PDXK
Fusion: TCGAAGPAT3 KSR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGPAT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGPAT3
dbVarAGPAT3
ClinVarAGPAT3
1000_GenomesAGPAT3 
Exome Variant ServerAGPAT3
ExAC (Exome Aggregation Consortium)AGPAT3 (select the gene name)
Genetic variants : HAPMAP56894
Genomic Variants (DGV)AGPAT3 [DGVbeta]
DECIPHER (Syndromes)21:45345279-45407475  ENSG00000160216
CONAN: Copy Number AnalysisAGPAT3 
Mutations
ICGC Data PortalAGPAT3 
TCGA Data PortalAGPAT3 
Broad Tumor PortalAGPAT3
OASIS PortalAGPAT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGPAT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGPAT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AGPAT3
DgiDB (Drug Gene Interaction Database)AGPAT3
DoCM (Curated mutations)AGPAT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGPAT3 (select a term)
intoGenAGPAT3
Cancer3DAGPAT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614794   
Orphanet
MedgenAGPAT3
Genetic Testing Registry AGPAT3
NextProtQ9NRZ7 [Medical]
TSGene56894
GENETestsAGPAT3
Huge Navigator AGPAT3 [HugePedia]
snp3D : Map Gene to Disease56894
BioCentury BCIQAGPAT3
ClinGenAGPAT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56894
Chemical/Pharm GKB GenePA24623
Clinical trialAGPAT3
Miscellaneous
canSAR (ICR)AGPAT3 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGPAT3
EVEXAGPAT3
GoPubMedAGPAT3
iHOPAGPAT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:53:56 CET 2017

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