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AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4)

Identity

Alias_names1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
Alias_symbol (synonym)LPAAT-delta
dJ473J16.2
Other alias1-AGPAT4
HGNC (Hugo) AGPAT4
LocusID (NCBI) 56895
Atlas_Id 60205
Location 6q26  [Link to chromosome band 6q26]
Location_base_pair Starts at 161130025 and ends at 161274075 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AGPAT4 (6q26) / AGPAT4 (6q26)AGPAT4 (6q26) / C12orf65 (12q24.31)AGPAT4 (6q26) / PARK2 (6q26)
PDE4D (5q11.2) / AGPAT4 (6q26)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGPAT4   20885
Cards
Entrez_Gene (NCBI)AGPAT4  56895  1-acylglycerol-3-phosphate O-acyltransferase 4
Aliases1-AGPAT4; LPAAT-delta; dJ473J16.2
GeneCards (Weizmann)AGPAT4
Ensembl hg19 (Hinxton)ENSG00000026652 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000026652 [Gene_View]  chr6:161130025-161274075 [Contig_View]  AGPAT4 [Vega]
ICGC DataPortalENSG00000026652
TCGA cBioPortalAGPAT4
AceView (NCBI)AGPAT4
Genatlas (Paris)AGPAT4
WikiGenes56895
SOURCE (Princeton)AGPAT4
Genetics Home Reference (NIH)AGPAT4
Genomic and cartography
GoldenPath hg38 (UCSC)AGPAT4  -     chr6:161130025-161274075 -  6q26   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AGPAT4  -     6q26   [Description]    (hg19-Feb_2009)
EnsemblAGPAT4 - 6q26 [CytoView hg19]  AGPAT4 - 6q26 [CytoView hg38]
Mapping of homologs : NCBIAGPAT4 [Mapview hg19]  AGPAT4 [Mapview hg38]
OMIM614795   
Gene and transcription
Genbank (Entrez)AF156776 AJ227890 AJ227891 AJ420473 AK074208
RefSeq transcript (Entrez)NM_001012733 NM_001012734 NM_020133
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AGPAT4
Cluster EST : UnigeneHs.353175 [ NCBI ]
CGAP (NCI)Hs.353175
Alternative Splicing GalleryENSG00000026652
Gene ExpressionAGPAT4 [ NCBI-GEO ]   AGPAT4 [ EBI - ARRAY_EXPRESS ]   AGPAT4 [ SEEK ]   AGPAT4 [ MEM ]
Gene Expression Viewer (FireBrowse)AGPAT4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56895
GTEX Portal (Tissue expression)AGPAT4
Human Protein AtlasENSG00000026652-AGPAT4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRZ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRZ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRZ5
Splice isoforms : SwissVarQ9NRZ5
Catalytic activity : Enzyme2.3.1.51 [ Enzyme-Expasy ]   2.3.1.512.3.1.51 [ IntEnz-EBI ]   2.3.1.51 [ BRENDA ]   2.3.1.51 [ KEGG ]   
PhosPhoSitePlusQ9NRZ5
Domains : Interpro (EBI)Acyltransf_C    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransf_C (PF16076)    Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam16076    pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)AGPAT4
DMDM Disease mutations56895
Blocks (Seattle)AGPAT4
SuperfamilyQ9NRZ5
Human Protein Atlas [tissue]ENSG00000026652-AGPAT4 [tissue]
Peptide AtlasQ9NRZ5
HPRD12437
IPIIPI00016956   IPI00910390   IPI00940010   IPI00465005   IPI00514976   IPI00514869   IPI00917647   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRZ5
IntAct (EBI)Q9NRZ5
FunCoupENSG00000026652
BioGRIDAGPAT4
STRING (EMBL)AGPAT4
ZODIACAGPAT4
Ontologies - Pathways
QuickGOQ9NRZ5
Ontology : AmiGO###############################################################################################################################################################################################################################################################                  
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                  
Pathways : KEGGGlycerophospholipid metabolism    Glycerolipid metabolism   
NDEx NetworkAGPAT4
Atlas of Cancer Signalling NetworkAGPAT4
Wikipedia pathwaysAGPAT4
Orthology - Evolution
OrthoDB56895
GeneTree (enSembl)ENSG00000026652
Phylogenetic Trees/Animal Genes : TreeFamAGPAT4
HOVERGENQ9NRZ5
HOGENOMQ9NRZ5
Homologs : HomoloGeneAGPAT4
Homology/Alignments : Family Browser (UCSC)AGPAT4
Gene fusions - Rearrangements
Fusion : QuiverAGPAT4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGPAT4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGPAT4
dbVarAGPAT4
ClinVarAGPAT4
1000_GenomesAGPAT4 
Exome Variant ServerAGPAT4
ExAC (Exome Aggregation Consortium)ENSG00000026652
GNOMAD BrowserENSG00000026652
Genetic variants : HAPMAP56895
Genomic Variants (DGV)AGPAT4 [DGVbeta]
DECIPHERAGPAT4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAGPAT4 
Mutations
ICGC Data PortalAGPAT4 
TCGA Data PortalAGPAT4 
Broad Tumor PortalAGPAT4
OASIS PortalAGPAT4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGPAT4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGPAT4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AGPAT4
DgiDB (Drug Gene Interaction Database)AGPAT4
DoCM (Curated mutations)AGPAT4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGPAT4 (select a term)
intoGenAGPAT4
Cancer3DAGPAT4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614795   
Orphanet
DisGeNETAGPAT4
MedgenAGPAT4
Genetic Testing Registry AGPAT4
NextProtQ9NRZ5 [Medical]
TSGene56895
GENETestsAGPAT4
Target ValidationAGPAT4
Huge Navigator AGPAT4 [HugePedia]
snp3D : Map Gene to Disease56895
BioCentury BCIQAGPAT4
ClinGenAGPAT4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56895
Chemical/Pharm GKB GenePA134961047
Clinical trialAGPAT4
Miscellaneous
canSAR (ICR)AGPAT4 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGPAT4
EVEXAGPAT4
GoPubMedAGPAT4
iHOPAGPAT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:10:31 CET 2018

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