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AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5)

Identity

Alias_namesepsilon
Alias_symbol (synonym)FLJ11210
LPAAT-e
LPAAT-epsilon
Other alias1AGPAT5
LPAATE
HGNC (Hugo) AGPAT5
LocusID (NCBI) 55326
Atlas_Id 52967
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 6708357 and ends at 6761500 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGPAT5 (8p23.1) / AGPAT5 (8p23.1)AGPAT5 (8p23.1) / HNRNPH3 (10q21.3)AGPAT5 (8p23.1) / MCPH1 (8p23.1)
AGPAT5 (8p23.1) / TXNDC16 (14q22.1)MCPH1 (8p23.1) / AGPAT5 (8p23.1)AGPAT5 8p23.1 / MCPH1 8p23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)AGPAT5   20886
Cards
Entrez_Gene (NCBI)AGPAT5  55326  1-acylglycerol-3-phosphate O-acyltransferase 5
Aliases1AGPAT5; LPAATE
GeneCards (Weizmann)AGPAT5
Ensembl hg19 (Hinxton)ENSG00000155189 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155189 [Gene_View]  chr8:6708357-6761500 [Contig_View]  AGPAT5 [Vega]
ICGC DataPortalENSG00000155189
TCGA cBioPortalAGPAT5
AceView (NCBI)AGPAT5
Genatlas (Paris)AGPAT5
WikiGenes55326
SOURCE (Princeton)AGPAT5
Genetics Home Reference (NIH)AGPAT5
Genomic and cartography
GoldenPath hg38 (UCSC)AGPAT5  -     chr8:6708357-6761500 +  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AGPAT5  -     8p23.1   [Description]    (hg19-Feb_2009)
EnsemblAGPAT5 - 8p23.1 [CytoView hg19]  AGPAT5 - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBIAGPAT5 [Mapview hg19]  AGPAT5 [Mapview hg38]
OMIM614796   
Gene and transcription
Genbank (Entrez)AF375789 AK002072 AK021722 AK310545 AL136587
RefSeq transcript (Entrez)NM_018361
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AGPAT5
Cluster EST : UnigeneHs.624002 [ NCBI ]
CGAP (NCI)Hs.624002
Alternative Splicing GalleryENSG00000155189
Gene ExpressionAGPAT5 [ NCBI-GEO ]   AGPAT5 [ EBI - ARRAY_EXPRESS ]   AGPAT5 [ SEEK ]   AGPAT5 [ MEM ]
Gene Expression Viewer (FireBrowse)AGPAT5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55326
GTEX Portal (Tissue expression)AGPAT5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NUQ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NUQ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NUQ2
Splice isoforms : SwissVarQ9NUQ2
Catalytic activity : Enzyme2.3.1.51 [ Enzyme-Expasy ]   2.3.1.512.3.1.51 [ IntEnz-EBI ]   2.3.1.51 [ BRENDA ]   2.3.1.51 [ KEGG ]   
PhosPhoSitePlusQ9NUQ2
Domains : Interpro (EBI)Acyltransf_C    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransf_C (PF16076)    Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam16076    pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)AGPAT5
DMDM Disease mutations55326
Blocks (Seattle)AGPAT5
SuperfamilyQ9NUQ2
Human Protein AtlasENSG00000155189
Peptide AtlasQ9NUQ2
HPRD12438
IPIIPI00028491   IPI00974034   IPI00975848   IPI00977014   
Protein Interaction databases
DIP (DOE-UCLA)Q9NUQ2
IntAct (EBI)Q9NUQ2
FunCoupENSG00000155189
BioGRIDAGPAT5
STRING (EMBL)AGPAT5
ZODIACAGPAT5
Ontologies - Pathways
QuickGOQ9NUQ2
Ontology : AmiGOhematopoietic progenitor cell differentiation  1-acylglycerol-3-phosphate O-acyltransferase activity  1-acylglycerol-3-phosphate O-acyltransferase activity  protein binding  nuclear envelope  mitochondrion  mitochondrial outer membrane  endoplasmic reticulum membrane  phosphatidic acid biosynthetic process  phospholipid biosynthetic process  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  
Ontology : EGO-EBIhematopoietic progenitor cell differentiation  1-acylglycerol-3-phosphate O-acyltransferase activity  1-acylglycerol-3-phosphate O-acyltransferase activity  protein binding  nuclear envelope  mitochondrion  mitochondrial outer membrane  endoplasmic reticulum membrane  phosphatidic acid biosynthetic process  phospholipid biosynthetic process  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  
NDEx NetworkAGPAT5
Atlas of Cancer Signalling NetworkAGPAT5
Wikipedia pathwaysAGPAT5
Orthology - Evolution
OrthoDB55326
GeneTree (enSembl)ENSG00000155189
Phylogenetic Trees/Animal Genes : TreeFamAGPAT5
HOVERGENQ9NUQ2
HOGENOMQ9NUQ2
Homologs : HomoloGeneAGPAT5
Homology/Alignments : Family Browser (UCSC)AGPAT5
Gene fusions - Rearrangements
Fusion : MitelmanAGPAT5/TXNDC16 [8p23.1/14q22.1]  
Fusion : MitelmanMCPH1/AGPAT5 [8p23.1/8p23.1]  [t(8;8)(p23;p23)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGPAT5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGPAT5
dbVarAGPAT5
ClinVarAGPAT5
1000_GenomesAGPAT5 
Exome Variant ServerAGPAT5
ExAC (Exome Aggregation Consortium)AGPAT5 (select the gene name)
Genetic variants : HAPMAP55326
Genomic Variants (DGV)AGPAT5 [DGVbeta]
DECIPHERAGPAT5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAGPAT5 
Mutations
ICGC Data PortalAGPAT5 
TCGA Data PortalAGPAT5 
Broad Tumor PortalAGPAT5
OASIS PortalAGPAT5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGPAT5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGPAT5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch AGPAT5
DgiDB (Drug Gene Interaction Database)AGPAT5
DoCM (Curated mutations)AGPAT5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGPAT5 (select a term)
intoGenAGPAT5
Cancer3DAGPAT5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614796   
Orphanet
MedgenAGPAT5
Genetic Testing Registry AGPAT5
NextProtQ9NUQ2 [Medical]
TSGene55326
GENETestsAGPAT5
Target ValidationAGPAT5
Huge Navigator AGPAT5 [HugePedia]
snp3D : Map Gene to Disease55326
BioCentury BCIQAGPAT5
ClinGenAGPAT5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55326
Chemical/Pharm GKB GenePA134952751
Clinical trialAGPAT5
Miscellaneous
canSAR (ICR)AGPAT5 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGPAT5
EVEXAGPAT5
GoPubMedAGPAT5
iHOPAGPAT5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:56:36 CEST 2017

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