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AGPS (alkylglycerone phosphate synthase)

Identity

Alias_symbol (synonym)ADHAPS
ADAS
ALDHPSY
ADPS
ADAP-S
Other aliasRCDP3
HGNC (Hugo) AGPS
LocusID (NCBI) 8540
Atlas_Id 53076
Location 2q31.2  [Link to chromosome band 2q31]
Location_base_pair Starts at 178257471 and ends at 178408564 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DNAAF5 (7p22.3) / AGPS (2q31.2)HNRNPAB (5q35.3) / AGPS (2q31.2)PRKRA (2q31.2) / AGPS (2q31.2)
RMI2 (16p13.13) / AGPS (2q31.2)PRKRA 2q31.2 / AGPS 2q31.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AGPS   327
Cards
Entrez_Gene (NCBI)AGPS  8540  alkylglycerone phosphate synthase
AliasesADAP-S; ADAS; ADHAPS; ADPS; 
ALDHPSY; RCDP3
GeneCards (Weizmann)AGPS
Ensembl hg19 (Hinxton)ENSG00000018510 [Gene_View]  chr2:178257471-178408564 [Contig_View]  AGPS [Vega]
Ensembl hg38 (Hinxton)ENSG00000018510 [Gene_View]  chr2:178257471-178408564 [Contig_View]  AGPS [Vega]
ICGC DataPortalENSG00000018510
TCGA cBioPortalAGPS
AceView (NCBI)AGPS
Genatlas (Paris)AGPS
WikiGenes8540
SOURCE (Princeton)AGPS
Genetics Home Reference (NIH)AGPS
Genomic and cartography
GoldenPath hg19 (UCSC)AGPS  -     chr2:178257471-178408564 +  2q31.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AGPS  -     2q31.2   [Description]    (hg38-Dec_2013)
EnsemblAGPS - 2q31.2 [CytoView hg19]  AGPS - 2q31.2 [CytoView hg38]
Mapping of homologs : NCBIAGPS [Mapview hg19]  AGPS [Mapview hg38]
OMIM600121   603051   
Gene and transcription
Genbank (Entrez)AA832354 AK296239 AK309714 AK314259 AK316240
RefSeq transcript (Entrez)NM_003659
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_008968 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)AGPS
Cluster EST : UnigeneHs.516543 [ NCBI ]
CGAP (NCI)Hs.516543
Alternative Splicing GalleryENSG00000018510
Gene ExpressionAGPS [ NCBI-GEO ]   AGPS [ EBI - ARRAY_EXPRESS ]   AGPS [ SEEK ]   AGPS [ MEM ]
Gene Expression Viewer (FireBrowse)AGPS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8540
GTEX Portal (Tissue expression)AGPS
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00116   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00116  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00116
Splice isoforms : SwissVarO00116
Catalytic activity : Enzyme2.5.1.26 [ Enzyme-Expasy ]   2.5.1.262.5.1.26 [ IntEnz-EBI ]   2.5.1.26 [ BRENDA ]   2.5.1.26 [ KEGG ]   
PhosPhoSitePlusO00116
Domaine pattern : Prosite (Expaxy)FAD_PCMH (PS51387)   
Domains : Interpro (EBI)Alkyl-DHAP_Synthase    CO_DH_flavot_FAD-bd_sub2    FAD-bd_2    FAD-bd_2_sub1    FAD-linked_Oxase-like_C    FAD-linked_oxidase_C    Oxid_FAD_bind_N   
Domain families : Pfam (Sanger)FAD-oxidase_C (PF02913)    FAD_binding_4 (PF01565)   
Domain families : Pfam (NCBI)pfam02913    pfam01565   
Conserved Domain (NCBI)AGPS
DMDM Disease mutations8540
Blocks (Seattle)AGPS
SuperfamilyO00116
Human Protein AtlasENSG00000018510
Peptide AtlasO00116
HPRD04337
IPIIPI00010349   IPI01014611   IPI00917312   
Protein Interaction databases
DIP (DOE-UCLA)O00116
IntAct (EBI)O00116
FunCoupENSG00000018510
BioGRIDAGPS
STRING (EMBL)AGPS
ZODIACAGPS
Ontologies - Pathways
QuickGOO00116
Ontology : AmiGOprotein binding  nucleolus  mitochondrion  peroxisome  peroxisomal membrane  peroxisomal matrix  alkylglycerone-phosphate synthase activity  lipid biosynthetic process  ether lipid biosynthetic process  ether lipid biosynthetic process  ether lipid biosynthetic process  membrane  oxidoreductase activity, acting on CH-OH group of donors  intracellular membrane-bounded organelle  oxidation-reduction process  FAD binding  
Ontology : EGO-EBIprotein binding  nucleolus  mitochondrion  peroxisome  peroxisomal membrane  peroxisomal matrix  alkylglycerone-phosphate synthase activity  lipid biosynthetic process  ether lipid biosynthetic process  ether lipid biosynthetic process  ether lipid biosynthetic process  membrane  oxidoreductase activity, acting on CH-OH group of donors  intracellular membrane-bounded organelle  oxidation-reduction process  FAD binding  
Pathways : KEGGEther lipid metabolism    Peroxisome   
NDEx NetworkAGPS
Atlas of Cancer Signalling NetworkAGPS
Wikipedia pathwaysAGPS
Orthology - Evolution
OrthoDB8540
GeneTree (enSembl)ENSG00000018510
Phylogenetic Trees/Animal Genes : TreeFamAGPS
HOVERGENO00116
HOGENOMO00116
Homologs : HomoloGeneAGPS
Homology/Alignments : Family Browser (UCSC)AGPS
Gene fusions - Rearrangements
Fusion : MitelmanPRKRA/AGPS [2q31.2/2q31.2]  [t(2;2)(q31;q31)]  
Fusion: TCGAPRKRA 2q31.2 AGPS 2q31.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAGPS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AGPS
dbVarAGPS
ClinVarAGPS
1000_GenomesAGPS 
Exome Variant ServerAGPS
ExAC (Exome Aggregation Consortium)AGPS (select the gene name)
Genetic variants : HAPMAP8540
Genomic Variants (DGV)AGPS [DGVbeta]
DECIPHER (Syndromes)2:178257471-178408564  ENSG00000018510
CONAN: Copy Number AnalysisAGPS 
Mutations
ICGC Data PortalAGPS 
TCGA Data PortalAGPS 
Broad Tumor PortalAGPS
OASIS PortalAGPS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAGPS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAGPS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch AGPS
DgiDB (Drug Gene Interaction Database)AGPS
DoCM (Curated mutations)AGPS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AGPS (select a term)
intoGenAGPS
Cancer3DAGPS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600121    603051   
Orphanet21390   
MedgenAGPS
Genetic Testing Registry AGPS
NextProtO00116 [Medical]
TSGene8540
GENETestsAGPS
Huge Navigator AGPS [HugePedia]
snp3D : Map Gene to Disease8540
BioCentury BCIQAGPS
ClinGenAGPS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8540
Chemical/Pharm GKB GenePA24624
Clinical trialAGPS
Miscellaneous
canSAR (ICR)AGPS (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAGPS
EVEXAGPS
GoPubMedAGPS
iHOPAGPS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:51:54 CEST 2017

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