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AHNAK (AHNAK nucleoprotein)

Identity

Alias_namesAHNAK nucleoprotein (desmoyokin)
Alias_symbol (synonym)MGC5395
Other aliasAHNAKRS
PM227
HGNC (Hugo) AHNAK
LocusID (NCBI) 79026
Atlas_Id 53725
Location 6q23.3  [Link to chromosome band 6q23]
Location_base_pair Starts at 62433542 and ends at 62546860 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AHNAK (11q12.3) / AHNAK (11q12.3)AHNAK (11q12.3) / ATP1A1 (1p13.1)AHNAK (11q12.3) / DLC1 (8p22)
AHNAK (11q12.3) / FBXL17 (5q21.3)AHNAK (11q12.3) / GPNMB (7p15.3)AHNAK (11q12.3) / GRIA3 (Xq25)
AHNAK (11q12.3) / RPS6KA4 (11q13.1)AHNAK (11q12.3) / STIP1 (11q13.1)AHNAK (11q12.3) / TPD52 (8q21.13)
AHNAK (11q12.3) / ZNF827 (4q31.21)AHNAK (11q12.3) / ZNFX1 (20q13.13)ARHGAP32 (11q24.3) / AHNAK (11q12.3)
FBXL17 (5q21.3) / AHNAK (11q12.3)GAPDH (12p13.31) / AHNAK (11q12.3)HNRNPUL2 (11q12.3) / AHNAK (11q12.3)
RPL21 (13q12.2) / AHNAK (11q12.3)TSPAN16 (19p13.2) / AHNAK (11q12.3)ZFHX3 (16q22.2) / AHNAK (11q12.3)
AHNAK 11q12.3 / RPS6KA4 11q13.1AHNAK 11q12.3 / STIP1 11q13.1AHNAK 11q12.3 / ZNF827 4q31.21
AHNAK 11q12.3 / ZNFX1 20q13.13ARHGAP32 11q24.3 / AHNAK 11q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 6 ]
  t(4;11)(q31;q12) AHNAK/ZNF827
HNRNPUL2/AHNAK (11q12)
t(11;11)(q12;q13) AHNAK/RPS6KA4
t(11;11)(q12;q13) AHNAK/STIP1
t(11;11)(q12;q24) ARHGAP32/AHNAK
t(11;20)(q12;q13) AHNAK/ZNFX1


External links

Nomenclature
HGNC (Hugo)AHNAK   347
Cards
Entrez_Gene (NCBI)AHNAK  79026  AHNAK nucleoprotein
AliasesAHNAKRS; PM227
GeneCards (Weizmann)AHNAK
Ensembl hg19 (Hinxton)ENSG00000124942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124942 [Gene_View]  ENSG00000124942 [Sequence]  chr11:62433542-62546860 [Contig_View]  AHNAK [Vega]
ICGC DataPortalENSG00000124942
TCGA cBioPortalAHNAK
AceView (NCBI)AHNAK
Genatlas (Paris)AHNAK
WikiGenes79026
SOURCE (Princeton)AHNAK
Genetics Home Reference (NIH)AHNAK
Genomic and cartography
GoldenPath hg38 (UCSC)AHNAK  -     chr11:62433542-62546860 -  6q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AHNAK  -     6q23.3   [Description]    (hg19-Feb_2009)
EnsemblAHNAK - 6q23.3 [CytoView hg19]  AHNAK - 6q23.3 [CytoView hg38]
Mapping of homologs : NCBIAHNAK [Mapview hg19]  AHNAK [Mapview hg38]
OMIM103390   
Gene and transcription
Genbank (Entrez)AK091153 AK095346 AK128868 AK300376 BC000926
RefSeq transcript (Entrez)NM_001346445 NM_001346446 NM_001620 NM_024060
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AHNAK
Cluster EST : UnigeneHs.502756 [ NCBI ]
CGAP (NCI)Hs.502756
Alternative Splicing GalleryENSG00000124942
Gene ExpressionAHNAK [ NCBI-GEO ]   AHNAK [ EBI - ARRAY_EXPRESS ]   AHNAK [ SEEK ]   AHNAK [ MEM ]
Gene Expression Viewer (FireBrowse)AHNAK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79026
GTEX Portal (Tissue expression)AHNAK
Human Protein AtlasENSG00000124942-AHNAK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ09666   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ09666  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ09666
Splice isoforms : SwissVarQ09666
PhosPhoSitePlusQ09666
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)PDZ    PDZ_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)AHNAK
DMDM Disease mutations79026
Blocks (Seattle)AHNAK
PDB (SRS)4DRW    4FTG    4HRG   
PDB (PDBSum)4DRW    4FTG    4HRG   
PDB (IMB)4DRW    4FTG    4HRG   
PDB (RSDB)4DRW    4FTG    4HRG   
Structural Biology KnowledgeBase4DRW    4FTG    4HRG   
SCOP (Structural Classification of Proteins)4DRW    4FTG    4HRG   
CATH (Classification of proteins structures)4DRW    4FTG    4HRG   
SuperfamilyQ09666
Human Protein Atlas [tissue]ENSG00000124942-AHNAK [tissue]
Peptide AtlasQ09666
HPRD14684
IPIIPI00021812   IPI00979442   IPI01012911   IPI00031605   IPI00975545   IPI00979461   IPI00981507   IPI00980977   IPI00978926   IPI00980133   
Protein Interaction databases
DIP (DOE-UCLA)Q09666
IntAct (EBI)Q09666
FunCoupENSG00000124942
BioGRIDAHNAK
STRING (EMBL)AHNAK
ZODIACAHNAK
Ontologies - Pathways
QuickGOQ09666
Ontology : AmiGORNA binding  protein binding  nucleus  nucleus  cytoplasm  cytoplasm  lysosomal membrane  cytosol  cytosol  plasma membrane  plasma membrane  focal adhesion  actin cytoskeleton  membrane  T-tubule  T-tubule  vesicle  sarcolemma  sarcolemma  costamere  costamere  regulation of RNA splicing  regulation of RNA splicing  cell-cell contact zone  S100 protein binding  membrane raft  cadherin binding  protein complex oligomerization  extracellular exosome  extracellular exosome  structural molecule activity conferring elasticity  regulation of voltage-gated calcium channel activity  
Ontology : EGO-EBIRNA binding  protein binding  nucleus  nucleus  cytoplasm  cytoplasm  lysosomal membrane  cytosol  cytosol  plasma membrane  plasma membrane  focal adhesion  actin cytoskeleton  membrane  T-tubule  T-tubule  vesicle  sarcolemma  sarcolemma  costamere  costamere  regulation of RNA splicing  regulation of RNA splicing  cell-cell contact zone  S100 protein binding  membrane raft  cadherin binding  protein complex oligomerization  extracellular exosome  extracellular exosome  structural molecule activity conferring elasticity  regulation of voltage-gated calcium channel activity  
NDEx NetworkAHNAK
Atlas of Cancer Signalling NetworkAHNAK
Wikipedia pathwaysAHNAK
Orthology - Evolution
OrthoDB79026
GeneTree (enSembl)ENSG00000124942
Phylogenetic Trees/Animal Genes : TreeFamAHNAK
HOVERGENQ09666
HOGENOMQ09666
Homologs : HomoloGeneAHNAK
Homology/Alignments : Family Browser (UCSC)AHNAK
Gene fusions - Rearrangements
Fusion : MitelmanAHNAK/RPS6KA4 [11q12.3/11q13.1]  
Fusion : MitelmanAHNAK/STIP1 [11q12.3/11q13.1]  [t(11;11)(q12;q13)]  
Fusion : MitelmanAHNAK/ZNF827 [11q12.3/4q31.21]  [t(4;11)(q31;q12)]  
Fusion : MitelmanAHNAK/ZNFX1 [11q12.3/20q13.13]  [t(11;20)(q12;q13)]  
Fusion : MitelmanARHGAP32/AHNAK [11q24.3/11q12.3]  [t(11;11)(q12;q24)]  
Fusion : MitelmanHNRNPUL2/AHNAK [11q12.3/11q12.3]  [t(11;11)(q12;q12)]  
Fusion PortalAHNAK 11q12.3 RPS6KA4 11q13.1 BRCA
Fusion PortalAHNAK 11q12.3 STIP1 11q13.1 LUAD
Fusion PortalAHNAK 11q12.3 ZNF827 4q31.21 BRCA
Fusion PortalAHNAK 11q12.3 ZNFX1 20q13.13 PRAD
Fusion PortalARHGAP32 11q24.3 AHNAK 11q12.3 BRCA
Fusion : QuiverAHNAK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAHNAK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AHNAK
dbVarAHNAK
ClinVarAHNAK
1000_GenomesAHNAK 
Exome Variant ServerAHNAK
ExAC (Exome Aggregation Consortium)ENSG00000124942
GNOMAD BrowserENSG00000124942
Varsome BrowserAHNAK
Genetic variants : HAPMAP79026
Genomic Variants (DGV)AHNAK [DGVbeta]
DECIPHERAHNAK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAHNAK 
Mutations
ICGC Data PortalAHNAK 
TCGA Data PortalAHNAK 
Broad Tumor PortalAHNAK
OASIS PortalAHNAK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAHNAK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAHNAK
intOGen PortalAHNAK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AHNAK
DgiDB (Drug Gene Interaction Database)AHNAK
DoCM (Curated mutations)AHNAK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AHNAK (select a term)
intoGenAHNAK
Cancer3DAHNAK(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103390   
Orphanet
DisGeNETAHNAK
MedgenAHNAK
Genetic Testing Registry AHNAK
NextProtQ09666 [Medical]
TSGene79026
GENETestsAHNAK
Target ValidationAHNAK
Huge Navigator AHNAK [HugePedia]
snp3D : Map Gene to Disease79026
BioCentury BCIQAHNAK
ClinGenAHNAK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79026
Chemical/Pharm GKB GenePA24640
Clinical trialAHNAK
Miscellaneous
canSAR (ICR)AHNAK (select the gene name)
Probes
Litterature
PubMed91 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAHNAK
EVEXAHNAK
GoPubMedAHNAK
iHOPAHNAK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Aug 16 10:45:58 CEST 2018

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