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AICDA (activation induced cytidine deaminase)

Identity

Alias_namesactivation-induced cytidine deaminase
Alias_symbol (synonym)HIGM2
CDA2
ARP2
AID
Other aliasHEL-S-284
HGNC (Hugo) AICDA
LocusID (NCBI) 57379
Atlas_Id 43110
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8602166 and ends at 8612867 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AICDA   13203
LRG (Locus Reference Genomic)LRG_17
Cards
Entrez_Gene (NCBI)AICDA  57379  activation induced cytidine deaminase
AliasesAID; ARP2; CDA2; HEL-S-284; 
HIGM2
GeneCards (Weizmann)AICDA
Ensembl hg19 (Hinxton)ENSG00000111732 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111732 [Gene_View]  chr12:8602166-8612867 [Contig_View]  AICDA [Vega]
ICGC DataPortalENSG00000111732
TCGA cBioPortalAICDA
AceView (NCBI)AICDA
Genatlas (Paris)AICDA
WikiGenes57379
SOURCE (Princeton)AICDA
Genetics Home Reference (NIH)AICDA
Genomic and cartography
GoldenPath hg38 (UCSC)AICDA  -     chr12:8602166-8612867 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AICDA  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblAICDA - 12p13.31 [CytoView hg19]  AICDA - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIAICDA [Mapview hg19]  AICDA [Mapview hg38]
OMIM605257   605258   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001330343 NM_020661
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AICDA
Cluster EST : UnigeneHs.149342 [ NCBI ]
CGAP (NCI)Hs.149342
Alternative Splicing GalleryENSG00000111732
Gene ExpressionAICDA [ NCBI-GEO ]   AICDA [ EBI - ARRAY_EXPRESS ]   AICDA [ SEEK ]   AICDA [ MEM ]
Gene Expression Viewer (FireBrowse)AICDA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57379
GTEX Portal (Tissue expression)AICDA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZX7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZX7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZX7
Splice isoforms : SwissVarQ9GZX7
PhosPhoSitePlusQ9GZX7
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)AICDA
DMDM Disease mutations57379
Blocks (Seattle)AICDA
PDB (SRS)5JJ4   
PDB (PDBSum)5JJ4   
PDB (IMB)5JJ4   
PDB (RSDB)5JJ4   
Structural Biology KnowledgeBase5JJ4   
SCOP (Structural Classification of Proteins)5JJ4   
CATH (Classification of proteins structures)5JJ4   
SuperfamilyQ9GZX7
Human Protein AtlasENSG00000111732
Peptide AtlasQ9GZX7
HPRD05585
IPIIPI00010186   IPI01011954   IPI00984850   IPI01014922   IPI01014454   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZX7
IntAct (EBI)Q9GZX7
FunCoupENSG00000111732
BioGRIDAICDA
STRING (EMBL)AICDA
ZODIACAICDA
Ontologies - Pathways
QuickGOQ9GZX7
Ontology : AmiGOexosome (RNase complex)  cytidine deaminase activity  cytidine deaminase activity  protein binding  nucleus  cytoplasm  mRNA processing  zinc ion binding  cytidine deamination  somatic diversification of immunoglobulins  somatic hypermutation of immunoglobulin genes  B cell differentiation  ubiquitin protein ligase binding  defense response to bacterium  isotype switching  cellular response to lipopolysaccharide  DNA demethylation  negative regulation of methylation-dependent chromatin silencing  
Ontology : EGO-EBIexosome (RNase complex)  cytidine deaminase activity  cytidine deaminase activity  protein binding  nucleus  cytoplasm  mRNA processing  zinc ion binding  cytidine deamination  somatic diversification of immunoglobulins  somatic hypermutation of immunoglobulin genes  B cell differentiation  ubiquitin protein ligase binding  defense response to bacterium  isotype switching  cellular response to lipopolysaccharide  DNA demethylation  negative regulation of methylation-dependent chromatin silencing  
Pathways : KEGGIntestinal immune network for IgA production    Primary immunodeficiency   
NDEx NetworkAICDA
Atlas of Cancer Signalling NetworkAICDA
Wikipedia pathwaysAICDA
Orthology - Evolution
OrthoDB57379
GeneTree (enSembl)ENSG00000111732
Phylogenetic Trees/Animal Genes : TreeFamAICDA
HOVERGENQ9GZX7
HOGENOMQ9GZX7
Homologs : HomoloGeneAICDA
Homology/Alignments : Family Browser (UCSC)AICDA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAICDA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AICDA
dbVarAICDA
ClinVarAICDA
1000_GenomesAICDA 
Exome Variant ServerAICDA
ExAC (Exome Aggregation Consortium)AICDA (select the gene name)
Genetic variants : HAPMAP57379
Genomic Variants (DGV)AICDA [DGVbeta]
DECIPHERAICDA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAICDA 
Mutations
ICGC Data PortalAICDA 
TCGA Data PortalAICDA 
Broad Tumor PortalAICDA
OASIS PortalAICDA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAICDA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAICDA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch AICDA
DgiDB (Drug Gene Interaction Database)AICDA
DoCM (Curated mutations)AICDA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AICDA (select a term)
intoGenAICDA
Cancer3DAICDA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605257    605258   
Orphanet14800   
MedgenAICDA
Genetic Testing Registry AICDA
NextProtQ9GZX7 [Medical]
TSGene57379
GENETestsAICDA
Target ValidationAICDA
Huge Navigator AICDA [HugePedia]
snp3D : Map Gene to Disease57379
BioCentury BCIQAICDA
ClinGenAICDA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57379
Chemical/Pharm GKB GenePA24644
Clinical trialAICDA
Miscellaneous
canSAR (ICR)AICDA (select the gene name)
Probes
Litterature
PubMed222 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAICDA
EVEXAICDA
GoPubMedAICDA
iHOPAICDA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:23:14 CEST 2017

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