Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AIFM3 (apoptosis inducing factor, mitochondria associated 3)

Identity

Alias_namesapoptosis-inducing factor
Alias_symbol (synonym)AIFL
FLJ30473
Other alias
HGNC (Hugo) AIFM3
LocusID (NCBI) 150209
Atlas_Id 45652
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 20965130 and ends at 20981360 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AIFM3   26398
Cards
Entrez_Gene (NCBI)AIFM3  150209  apoptosis inducing factor, mitochondria associated 3
AliasesAIFL
GeneCards (Weizmann)AIFM3
Ensembl hg19 (Hinxton)ENSG00000183773 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183773 [Gene_View]  chr22:20965130-20981360 [Contig_View]  AIFM3 [Vega]
ICGC DataPortalENSG00000183773
TCGA cBioPortalAIFM3
AceView (NCBI)AIFM3
Genatlas (Paris)AIFM3
WikiGenes150209
SOURCE (Princeton)AIFM3
Genetics Home Reference (NIH)AIFM3
Genomic and cartography
GoldenPath hg38 (UCSC)AIFM3  -     chr22:20965130-20981360 +  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AIFM3  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblAIFM3 - 22q11.21 [CytoView hg19]  AIFM3 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBIAIFM3 [Mapview hg19]  AIFM3 [Mapview hg38]
OMIM617298   
Gene and transcription
Genbank (Entrez)AK055035 AK094844 AK126917 AK295581 AK316042
RefSeq transcript (Entrez)NM_001018060 NM_001146288 NM_144704
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AIFM3
Cluster EST : UnigeneHs.723246 [ NCBI ]
CGAP (NCI)Hs.723246
Alternative Splicing GalleryENSG00000183773
Gene ExpressionAIFM3 [ NCBI-GEO ]   AIFM3 [ EBI - ARRAY_EXPRESS ]   AIFM3 [ SEEK ]   AIFM3 [ MEM ]
Gene Expression Viewer (FireBrowse)AIFM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)150209
GTEX Portal (Tissue expression)AIFM3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NN9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96NN9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96NN9
Splice isoforms : SwissVarQ96NN9
Catalytic activity : Enzyme1.-.-.- [ Enzyme-Expasy ]   1.-.-.-1.-.-.- [ IntEnz-EBI ]   1.-.-.- [ BRENDA ]   1.-.-.- [ KEGG ]   
PhosPhoSitePlusQ96NN9
Domaine pattern : Prosite (Expaxy)RIESKE (PS51296)   
Domains : Interpro (EBI)FAD/NAD-binding_dom    FAD/NAD-linked_Rdtase_dimer    Pyr_nucl-diS_OxRdtase_dimer    Pyridine_nuc-diS_OxRdtase_2    Reductase_C    Rieske_2Fe-2S   
Domain families : Pfam (Sanger)Pyr_redox_2 (PF07992)    Reductase_C (PF14759)    Rieske (PF00355)   
Domain families : Pfam (NCBI)pfam07992    pfam14759    pfam00355   
Conserved Domain (NCBI)AIFM3
DMDM Disease mutations150209
Blocks (Seattle)AIFM3
SuperfamilyQ96NN9
Human Protein AtlasENSG00000183773
Peptide AtlasQ96NN9
HPRD08085
IPIIPI00043760   IPI00793477   IPI00384348   IPI00922572   IPI00880026   IPI00878232   IPI00877730   IPI00878495   
Protein Interaction databases
DIP (DOE-UCLA)Q96NN9
IntAct (EBI)Q96NN9
FunCoupENSG00000183773
BioGRIDAIFM3
STRING (EMBL)AIFM3
ZODIACAIFM3
Ontologies - Pathways
QuickGOQ96NN9
Ontology : AmiGOnucleus  mitochondrion  mitochondrial inner membrane  endoplasmic reticulum  cytosol  oxidoreductase activity  metal ion binding  flavin adenine dinucleotide binding  2 iron, 2 sulfur cluster binding  oxidation-reduction process  execution phase of apoptosis  
Ontology : EGO-EBInucleus  mitochondrion  mitochondrial inner membrane  endoplasmic reticulum  cytosol  oxidoreductase activity  metal ion binding  flavin adenine dinucleotide binding  2 iron, 2 sulfur cluster binding  oxidation-reduction process  execution phase of apoptosis  
NDEx NetworkAIFM3
Atlas of Cancer Signalling NetworkAIFM3
Wikipedia pathwaysAIFM3
Orthology - Evolution
OrthoDB150209
GeneTree (enSembl)ENSG00000183773
Phylogenetic Trees/Animal Genes : TreeFamAIFM3
HOVERGENQ96NN9
HOGENOMQ96NN9
Homologs : HomoloGeneAIFM3
Homology/Alignments : Family Browser (UCSC)AIFM3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAIFM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AIFM3
dbVarAIFM3
ClinVarAIFM3
1000_GenomesAIFM3 
Exome Variant ServerAIFM3
ExAC (Exome Aggregation Consortium)AIFM3 (select the gene name)
Genetic variants : HAPMAP150209
Genomic Variants (DGV)AIFM3 [DGVbeta]
DECIPHERAIFM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAIFM3 
Mutations
ICGC Data PortalAIFM3 
TCGA Data PortalAIFM3 
Broad Tumor PortalAIFM3
OASIS PortalAIFM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAIFM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAIFM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch AIFM3
DgiDB (Drug Gene Interaction Database)AIFM3
DoCM (Curated mutations)AIFM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AIFM3 (select a term)
intoGenAIFM3
Cancer3DAIFM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617298   
Orphanet
MedgenAIFM3
Genetic Testing Registry AIFM3
NextProtQ96NN9 [Medical]
TSGene150209
GENETestsAIFM3
Huge Navigator AIFM3 [HugePedia]
snp3D : Map Gene to Disease150209
BioCentury BCIQAIFM3
ClinGenAIFM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD150209
Chemical/Pharm GKB GenePA162376173
Clinical trialAIFM3
Miscellaneous
canSAR (ICR)AIFM3 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAIFM3
EVEXAIFM3
GoPubMedAIFM3
iHOPAIFM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:05:28 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.