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AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2)

Identity

Alias_symbol (synonym)p38
PRO0992
JTV-1
JTV1
Other aliasP38
HGNC (Hugo) AIMP2
LocusID (NCBI) 7965
Atlas_Id 53099
Location 7p22.1  [Link to chromosome band 7p22]
Location_base_pair Starts at 6009251 and ends at 6023834 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AIMP2 (7p22.1) / AIMP2 (7p22.1)AIMP2 (7p22.1) / EIF2AK1 (7p22.1)PMS2 (7p22.1) / AIMP2 (7p22.1)
PMS2 7p22.1 / AIMP2 7p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AIMP2   20609
Cards
Entrez_Gene (NCBI)AIMP2  7965  aminoacyl tRNA synthetase complex interacting multifunctional protein 2
AliasesJTV-1; JTV1; P38
GeneCards (Weizmann)AIMP2
Ensembl hg19 (Hinxton)ENSG00000106305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106305 [Gene_View]  chr7:6009251-6023834 [Contig_View]  AIMP2 [Vega]
ICGC DataPortalENSG00000106305
TCGA cBioPortalAIMP2
AceView (NCBI)AIMP2
Genatlas (Paris)AIMP2
WikiGenes7965
SOURCE (Princeton)AIMP2
Genetics Home Reference (NIH)AIMP2
Genomic and cartography
GoldenPath hg38 (UCSC)AIMP2  -     chr7:6009251-6023834 +  7p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AIMP2  -     7p22.1   [Description]    (hg19-Feb_2009)
EnsemblAIMP2 - 7p22.1 [CytoView hg19]  AIMP2 - 7p22.1 [CytoView hg38]
Mapping of homologs : NCBIAIMP2 [Mapview hg19]  AIMP2 [Mapview hg38]
OMIM600859   
Gene and transcription
Genbank (Entrez)AK313037 BC002853 BC010156 BC013630 CX867709
RefSeq transcript (Entrez)NM_001326606 NM_001326607 NM_001326609 NM_001326610 NM_001326611 NM_006303 NM_018570
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AIMP2
Cluster EST : UnigeneHs.301613 [ NCBI ]
CGAP (NCI)Hs.301613
Alternative Splicing GalleryENSG00000106305
Gene ExpressionAIMP2 [ NCBI-GEO ]   AIMP2 [ EBI - ARRAY_EXPRESS ]   AIMP2 [ SEEK ]   AIMP2 [ MEM ]
Gene Expression Viewer (FireBrowse)AIMP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7965
GTEX Portal (Tissue expression)AIMP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13155   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13155  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13155
Splice isoforms : SwissVarQ13155
PhosPhoSitePlusQ13155
Domains : Interpro (EBI)AIMP2_LysRS-bd    Glutathione-S-Trfase_C-like    GST_C   
Domain families : Pfam (Sanger)AIMP2_LysRS_bd (PF16780)    GST_C (PF00043)   
Domain families : Pfam (NCBI)pfam16780    pfam00043   
Conserved Domain (NCBI)AIMP2
DMDM Disease mutations7965
Blocks (Seattle)AIMP2
PDB (SRS)4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
PDB (PDBSum)4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
PDB (IMB)4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
PDB (RSDB)4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
Structural Biology KnowledgeBase4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
SCOP (Structural Classification of Proteins)4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
CATH (Classification of proteins structures)4DPG    4YCU    4YCW    5A1N    5A34    5A5H   
SuperfamilyQ13155
Human Protein AtlasENSG00000106305
Peptide AtlasQ13155
HPRD02915
IPIIPI00011916   IPI00893909   IPI00893242   IPI00893993   
Protein Interaction databases
DIP (DOE-UCLA)Q13155
IntAct (EBI)Q13155
FunCoupENSG00000106305
BioGRIDAIMP2
STRING (EMBL)AIMP2
ZODIACAIMP2
Ontologies - Pathways
QuickGOQ13155
Ontology : AmiGOprotein binding  nucleus  cytosol  tRNA aminoacylation for protein translation  protein complex assembly  apoptotic process  negative regulation of cell proliferation  membrane  aminoacyl-tRNA synthetase multienzyme complex  positive regulation of protein ubiquitination  protein complex scaffold  Type II pneumocyte differentiation  positive regulation of neuron death  positive regulation of aminoacyl-tRNA ligase activity  
Ontology : EGO-EBIprotein binding  nucleus  cytosol  tRNA aminoacylation for protein translation  protein complex assembly  apoptotic process  negative regulation of cell proliferation  membrane  aminoacyl-tRNA synthetase multienzyme complex  positive regulation of protein ubiquitination  protein complex scaffold  Type II pneumocyte differentiation  positive regulation of neuron death  positive regulation of aminoacyl-tRNA ligase activity  
NDEx NetworkAIMP2
Atlas of Cancer Signalling NetworkAIMP2
Wikipedia pathwaysAIMP2
Orthology - Evolution
OrthoDB7965
GeneTree (enSembl)ENSG00000106305
Phylogenetic Trees/Animal Genes : TreeFamAIMP2
HOVERGENQ13155
HOGENOMQ13155
Homologs : HomoloGeneAIMP2
Homology/Alignments : Family Browser (UCSC)AIMP2
Gene fusions - Rearrangements
Fusion : MitelmanPMS2/AIMP2 [7p22.1/7p22.1]  [t(7;7)(p22;p22)]  
Fusion: TCGAPMS2 7p22.1 AIMP2 7p22.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAIMP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AIMP2
dbVarAIMP2
ClinVarAIMP2
1000_GenomesAIMP2 
Exome Variant ServerAIMP2
ExAC (Exome Aggregation Consortium)AIMP2 (select the gene name)
Genetic variants : HAPMAP7965
Genomic Variants (DGV)AIMP2 [DGVbeta]
DECIPHERAIMP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAIMP2 
Mutations
ICGC Data PortalAIMP2 
TCGA Data PortalAIMP2 
Broad Tumor PortalAIMP2
OASIS PortalAIMP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAIMP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAIMP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AIMP2
DgiDB (Drug Gene Interaction Database)AIMP2
DoCM (Curated mutations)AIMP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AIMP2 (select a term)
intoGenAIMP2
Cancer3DAIMP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600859   
Orphanet
MedgenAIMP2
Genetic Testing Registry AIMP2
NextProtQ13155 [Medical]
TSGene7965
GENETestsAIMP2
Target ValidationAIMP2
Huge Navigator AIMP2 [HugePedia]
snp3D : Map Gene to Disease7965
BioCentury BCIQAIMP2
ClinGenAIMP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7965
Chemical/Pharm GKB GenePA165617609
Clinical trialAIMP2
Miscellaneous
canSAR (ICR)AIMP2 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAIMP2
EVEXAIMP2
GoPubMedAIMP2
iHOPAIMP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:54:41 CEST 2017

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