| Nomenclature | | HGNC (Hugo) | AIRE 360 |
| Entrez_Gene (NCBI) | AIRE 326 autoimmune regulator |
| Cards | | GeneCards (Weizmann) | AIRE |
| Ensembl (Hinxton) | ENSG00000160224 [Gene_View] chr21:45705721-45718102 [Contig_View] AIRE [Vega] |
| AceView (NCBI) | AIRE |
| Genatlas (Paris) | AIRE |
| SOURCE (Stanford) | NM_000383 NM_000658 NM_000659 |
| Genomic and cartography | | GoldenPath (UCSC) | AIRE - 21q22.3 chr21:45705721-45718102 + 21q22.3 [Description] (hg19-Feb_2009) |
| Ensembl | AIRE - 21q22.3 [CytoView] |
| Mapping of homologs : NCBI | AIRE [Mapview] |
| OMIM | 240300 607358 |
| Gene and transcription |
| Genbank (Entrez) | AB006682 AB006683 AB006685 AK309572 BC137268 |
| RefSeq transcript (SRS) | NM_000383 NM_000658 NM_000659 |
| RefSeq transcript (Entrez) | NM_000383 NM_000658 NM_000659 |
| RefSeq genomic (SRS) | AC_000153 NC_000021 NC_018932 NG_009556 NT_011515 NW_001838716 NW_004078109 |
| RefSeq genomic (Entrez) | AC_000153 NC_000021 NC_018932 NG_009556 NT_011515 NW_001838716 NW_004078109 |
| Consensus coding sequences : CCDS (NCBI) | AIRE |
| Cluster EST : Unigene | Hs.129829 [ SRS ] Hs.129829 [ NCBI ] |
| CGAP (NCI) | Hs.129829 |
| Alternative Splicing : Fast-db (Paris) | GSHG0019533 |
| Alternative Splicing Gallery | ENSG00000160224 |
| Gene Expression | AIRE [ NCBI-GEO ] AIRE [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O43918 (SRS) O43918 (Uniprot) |
| NextProt | O43918 |
| With graphics : InterPro | O43918 |
| Splice isoforms : SwissVar | O43918(Swissvar) |
| Domaine pattern : Prosite (SRS) | HSR (PS51414) SAND (PS50864) ZF_PHD_1 (PS01359) ZF_PHD_2 (PS50016) |
| Domaine pattern : Prosite (Expaxy) | HSR (PS51414) SAND (PS50864) ZF_PHD_1 (PS01359) ZF_PHD_2 (PS50016) |
| Domains : Interpro (SRS) | AIRE SAND_dom SAND_dom-like Sp100 Zinc_finger_PHD-type_CS Znf_FYVE_PHD Znf_PHD Znf_PHD-finger Znf_RING/FYVE/PHD |
| Domains : Interpro (EBI) | AIRE SAND_dom SAND_dom-like Sp100 Zinc_finger_PHD-type_CS Znf_FYVE_PHD Znf_PHD Znf_PHD-finger Znf_RING/FYVE/PHD |
| Related proteins : CluSTr | O43918 |
| Domain families : Pfam (SRS) | PHD (PF00628) SAND (PF01342) Sp100 (PF03172) |
| Domain families : Pfam (Sanger) | PHD (PF00628) SAND (PF01342) Sp100 (PF03172) |
| Domain families : Pfam (NCBI) | pfam00628 pfam01342 pfam03172 |
| Domain families : Smart (EMBL) | PHD (SM00249) SAND (SM00258) |
| DMDM | 326 |
| Blocks (Seattle) | O43918 |
| PDB (SRS) | 1XWH 2KE1 2KFT |
| PDB (PDBSum) | 1XWH 2KE1 2KFT |
| PDB (IMB) | 1XWH 2KE1 2KFT |
| PDB (RSDB) | 1XWH 2KE1 2KFT |
| Human Protein Atlas | ENSG00000160224 |
| HPRD | 06301 |
| IPI | IPI00015149 IPI00480202 IPI00031178 IPI00031188 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O43918 |
| IntAct (EBI) | O43918 |
| FunCoup | ENSG00000160224 |
| REACTOME | AIRE |
| Protein Interaction Database | 326 |
| BioGRID | AIRE |
| InParanoid | O43918 |
| Interologous Interaction database | O43918 |
| IntegromeDB | AIRE |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | AIRE |
| SNP (GeneSNP Utah) | AIRE |
| SNP : HGBase | AIRE |
| Genetic variants : HAPMAP | AIRE |
| Somatic Mutations in Cancer : COSMIC | AIRE |
| CONAN: Copy Number Analysis | AIRE |
| Mutations and Diseases : HGMD | AIRE |
| OMIM | 240300 607358 |
| GENETests | 240300 607358 |
| Disease Genetic Association | AIRE |
| Huge Navigator |
AIRE [HugePedia] AIRE [HugeCancerGEM] |
| Genomic Variants | AIRE AIRE [DGVbeta] |
| snp3D : Map Gene to Disease | 326 |
| General knowledge |
|---|
| Homologs : HomoloGene | AIRE |
| Homology/Alignments : Family Browser (UCSC) | AIRE |
| Phylogenetic Trees/Animal Genes : TreeFam | AIRE |
| Chemical/Protein Interactions : CTD | 326 |
| Chemical/Pharm GKB Gene | PA24654 |
| Clinical trial | AIRE |
| Cancer Resource (Charite) | ENSG00000160224 |
| Ontology : AmiGO | chromatin binding protein binding nucleus nucleus nucleolus cytoplasm plasma membrane transcription, DNA-dependent regulation of transcription, DNA-dependent immune response humoral immune response zinc ion binding actin cytoskeleton histone binding identical protein binding transcription regulatory region DNA binding translation regulator activity positive regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter metal ion binding |
| Ontology : EGO-EBI | chromatin binding protein binding nucleus nucleus nucleolus cytoplasm plasma membrane transcription, DNA-dependent regulation of transcription, DNA-dependent immune response humoral immune response zinc ion binding actin cytoskeleton histone binding identical protein binding transcription regulatory region DNA binding translation regulator activity positive regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter metal ion binding |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 117 Pubmed reference(s) in Entrez |
| PubGene | AIRE |
| iHOP | AIRE |
