AJAP1 (adherens junctions associated protein 1)

2007-02-01 Affiliation

Identity

HGNC

AJAP1

LOCATION

1p36.32

LOCUSID

55966

ALIAS

MOT8,SHREW-1,SHREW1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 55966
MIM: 610972
HGNC: 30801
Ensembl: ENSG00000196581

Variants:

dbSNP: 55966
ClinVar: 55966
TCGA: ENSG00000196581
COSMIC: AJAP1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196581	ENST00000378190	Q9UKB5
ENSG00000196581	ENST00000378191	Q9UKB5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19240061	2009	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	75
19850283	2010	Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.	27
23064961	2013	GWAS of dental caries patterns in the permanent dentition.	27
17267690	2007	Junction protein shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147.	23
22241217	2012	Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.	21
16410724	2006	The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration.	18
26122373	2015	Reduced Expression of Adherens Junctions Associated Protein 1 Predicts Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy.	14
26397940	2015	Adherens junctions associated protein 1 serves as a predictor of recurrence of squamous cell carcinoma of the esophagus.	13
16707570	2006	Targeting of transmembrane protein shrew-1 to adherens junctions is controlled by cytoplasmic sorting motifs.	11
19515834	2009	E-cadherin surface levels in epithelial growth factor-stimulated cells depend on adherens junction protein shrew-1.	10

Citation

Dessen P

AJAP1 (adherens junctions associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45790/ajap1