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AK1 (adenylate kinase 1)

Identity

Other aliasHTL-S-58j
HGNC (Hugo) AK1
LocusID (NCBI) 203
Atlas_Id 43111
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 127866480 and ends at 127877743 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AK1   361
Cards
Entrez_Gene (NCBI)AK1  203  adenylate kinase 1
AliasesHTL-S-58j
GeneCards (Weizmann)AK1
Ensembl hg19 (Hinxton)ENSG00000106992 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106992 [Gene_View]  chr9:127866480-127877743 [Contig_View]  AK1 [Vega]
ICGC DataPortalENSG00000106992
TCGA cBioPortalAK1
AceView (NCBI)AK1
Genatlas (Paris)AK1
WikiGenes203
SOURCE (Princeton)AK1
Genetics Home Reference (NIH)AK1
Genomic and cartography
GoldenPath hg38 (UCSC)AK1  -     chr9:127866480-127877743 -  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AK1  -     9q34.11   [Description]    (hg19-Feb_2009)
EnsemblAK1 - 9q34.11 [CytoView hg19]  AK1 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIAK1 [Mapview hg19]  AK1 [Mapview hg38]
OMIM103000   612631   
Gene and transcription
Genbank (Entrez)AB021871 AK223501 AK313758 BC001116 BC036803
RefSeq transcript (Entrez)NM_000476 NM_001318121 NM_001318122
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AK1
Cluster EST : UnigeneHs.175473 [ NCBI ]
CGAP (NCI)Hs.175473
Alternative Splicing GalleryENSG00000106992
Gene ExpressionAK1 [ NCBI-GEO ]   AK1 [ EBI - ARRAY_EXPRESS ]   AK1 [ SEEK ]   AK1 [ MEM ]
Gene Expression Viewer (FireBrowse)AK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)203
GTEX Portal (Tissue expression)AK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00568   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP00568  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00568
Splice isoforms : SwissVarP00568
PhosPhoSitePlusP00568
Domaine pattern : Prosite (Expaxy)ADENYLATE_KINASE (PS00113)   
Domains : Interpro (EBI)Adenylat/UMP-CMP_kin    Adenylat_kinase_CS    AK1    AK1/5    P-loop_NTPase   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)AK1
DMDM Disease mutations203
Blocks (Seattle)AK1
PDB (SRS)1Z83    2C95   
PDB (PDBSum)1Z83    2C95   
PDB (IMB)1Z83    2C95   
PDB (RSDB)1Z83    2C95   
Structural Biology KnowledgeBase1Z83    2C95   
SCOP (Structural Classification of Proteins)1Z83    2C95   
CATH (Classification of proteins structures)1Z83    2C95   
SuperfamilyP00568
Human Protein AtlasENSG00000106992
Peptide AtlasP00568
HPRD00046
IPIIPI00018342   IPI01022753   IPI01021423   IPI00640817   IPI00515036   
Protein Interaction databases
DIP (DOE-UCLA)P00568
IntAct (EBI)P00568
FunCoupENSG00000106992
BioGRIDAK1
STRING (EMBL)AK1
ZODIACAK1
Ontologies - Pathways
QuickGOP00568
Ontology : AmiGOadenylate kinase activity  nucleoside diphosphate kinase activity  ATP binding  cytosol  cytosol  nucleoside diphosphate phosphorylation  nucleoside triphosphate biosynthetic process  nucleobase-containing small molecule interconversion  ATP metabolic process  extracellular exosome  
Ontology : EGO-EBIadenylate kinase activity  nucleoside diphosphate kinase activity  ATP binding  cytosol  cytosol  nucleoside diphosphate phosphorylation  nucleoside triphosphate biosynthetic process  nucleobase-containing small molecule interconversion  ATP metabolic process  extracellular exosome  
Pathways : KEGGPurine metabolism   
NDEx NetworkAK1
Atlas of Cancer Signalling NetworkAK1
Wikipedia pathwaysAK1
Orthology - Evolution
OrthoDB203
GeneTree (enSembl)ENSG00000106992
Phylogenetic Trees/Animal Genes : TreeFamAK1
HOVERGENP00568
HOGENOMP00568
Homologs : HomoloGeneAK1
Homology/Alignments : Family Browser (UCSC)AK1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AK1
dbVarAK1
ClinVarAK1
1000_GenomesAK1 
Exome Variant ServerAK1
ExAC (Exome Aggregation Consortium)AK1 (select the gene name)
Genetic variants : HAPMAP203
Genomic Variants (DGV)AK1 [DGVbeta]
DECIPHERAK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAK1 
Mutations
ICGC Data PortalAK1 
TCGA Data PortalAK1 
Broad Tumor PortalAK1
OASIS PortalAK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AK1
DgiDB (Drug Gene Interaction Database)AK1
DoCM (Curated mutations)AK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AK1 (select a term)
intoGenAK1
Cancer3DAK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103000    612631   
Orphanet11737   
MedgenAK1
Genetic Testing Registry AK1
NextProtP00568 [Medical]
TSGene203
GENETestsAK1
Target ValidationAK1
Huge Navigator AK1 [HugePedia]
snp3D : Map Gene to Disease203
BioCentury BCIQAK1
ClinGenAK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD203
Chemical/Pharm GKB GenePA24655
Clinical trialAK1
Miscellaneous
canSAR (ICR)AK1 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAK1
EVEXAK1
GoPubMedAK1
iHOPAK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:56:45 CEST 2017

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