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AK5 (adenylate kinase 5)

Identity

Other namesAK6
HGNC (Hugo) AK5
LocusID (NCBI) 26289
Location 1p31.1
Location_base_pair Starts at 77748287 and ends at 78025654 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)AK5   365
Entrez_Gene (NCBI)AK5  26289  adenylate kinase 5
Cards
GeneCards (Weizmann)AK5
Ensembl (Hinxton)ENSG00000154027 [Gene_View]  chr1:77748287-78025654 [Contig_View]  AK5 [Vega]
AceView (NCBI)AK5
Genatlas (Paris)AK5
SOURCE (Stanford)NM_012093 NM_174858
Genomic and cartography
GoldenPath (UCSC)AK5  -  1p31.1   chr1:77748287-78025654 +  1p31.1   [Description]    (hg19-Feb_2009)
EnsemblAK5 - 1p31.1 [CytoView]
Mapping of homologs : NCBIAK5 [Mapview]
OMIM608009   
Gene and transcription
Genbank (Entrez)AF062595 AF445193 AK090967 AW665223 AY171600
RefSeq transcript (SRS)NM_012093 NM_174858
RefSeq transcript (Entrez)NM_012093 NM_174858
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NT_032977 NW_001838579 NW_004077990
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_032977 NW_001838579 NW_004077990
Consensus coding sequences : CCDS (NCBI)AK5
Cluster EST : UnigeneHs.597002 [ SRS ] Hs.597002 [ NCBI ]
CGAP (NCI)Hs.597002
Alternative Splicing : Fast-db (Paris)GSHG0000644
Alternative Splicing GalleryENSG00000154027
Gene ExpressionAK5 [ NCBI-GEO ]   AK5 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6K8 (SRS) Q9Y6K8 (Uniprot)
NextProtQ9Y6K8
With graphics : InterProQ9Y6K8
Splice isoforms : SwissVarQ9Y6K8(Swissvar)
Domaine pattern : Prosite (SRS)ADENYLATE_KINASE (PS00113)   
Domaine pattern : Prosite (Expaxy)ADENYLATE_KINASE (PS00113)   
Domains : Interpro (SRS)Adenylate_kin    Adenylate_kin1    cAMP_dep_PK_reg_su_I/II_a/b    Dpy-30_motif   
Domains : Interpro (EBI)Adenylate_kin    Adenylate_kin1    cAMP_dep_PK_reg_su_I/II_a/b    Dpy-30_motif   
Related proteins : CluSTrQ9Y6K8
Domain families : Pfam (SRS)ADK (PF00406)    Dpy-30 (PF05186)   
Domain families : Pfam (Sanger)ADK (PF00406)    Dpy-30 (PF05186)   
Domain families : Pfam (NCBI)pfam00406    pfam05186   
DMDM26289
Blocks (Seattle)Q9Y6K8
PDB (SRS)2BWJ   
PDB (PDBSum)2BWJ   
PDB (IMB)2BWJ   
PDB (RSDB)2BWJ   
Human Protein AtlasENSG00000154027
HPRD10472
IPIIPI00943762   IPI00844054   IPI00166342   IPI00743623   IPI00975722   IPI00980215   IPI01008811   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6K8
IntAct (EBI)Q9Y6K8
FunCoupENSG00000154027
REACTOMEAK5
Protein Interaction Database26289
BioGRIDAK5
InParanoidQ9Y6K8
Interologous Interaction database Q9Y6K8
IntegromeDBAK5
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)AK5
SNP (GeneSNP Utah)AK5
SNP : HGBaseAK5
Genetic variants : HAPMAPAK5
Somatic Mutations in Cancer : COSMICAK5 
CONAN: Copy Number AnalysisAK5 
Mutations and Diseases : HGMDAK5
OMIM608009   
GENETests608009   
Disease Genetic AssociationAK5
Huge Navigator AK5 [HugePedia]  AK5 [HugeCancerGEM]
Genomic VariantsAK5  AK5 [DGVbeta]
snp3D : Map Gene to Disease26289
General knowledge
Homologs : HomoloGeneAK5
Homology/Alignments : Family Browser (UCSC)AK5
Phylogenetic Trees/Animal Genes : TreeFamAK5
Catalytic activity : Enzyme2.7.4.3 [ Enzyme-Expasy ]   2.7.4.3 [ Enzyme-SRS ]   2.7.4.3 [ IntEnz-EBI ]   2.7.4.3 [ BRENDA ]   2.7.4.3 [ KEGG ]   
Chemical/Protein Interactions : CTD26289
Chemical/Pharm GKB GenePA24659
Clinical trialAK5
Cancer Resource (Charite)ENSG00000154027
Ontology : AmiGOadenylate kinase activity  ATP binding  cytoplasm  centrosome  cytosol  ADP biosynthetic process  dADP biosynthetic process  signal transduction  cAMP-dependent protein kinase regulator activity  pyrimidine ribonucleotide biosynthetic process  nucleobase-containing small molecule interconversion  nucleoside kinase activity  small molecule metabolic process  ATP metabolic process  nucleobase-containing small molecule metabolic process  
Ontology : EGO-EBIadenylate kinase activity  ATP binding  cytoplasm  centrosome  cytosol  ADP biosynthetic process  dADP biosynthetic process  signal transduction  cAMP-dependent protein kinase regulator activity  pyrimidine ribonucleotide biosynthetic process  nucleobase-containing small molecule interconversion  nucleoside kinase activity  small molecule metabolic process  ATP metabolic process  nucleobase-containing small molecule metabolic process  
Pathways : KEGGPurine metabolism
Other databases
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
PubGeneAK5
iHOPAK5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:25:04 CEST 2013
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