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AKAIN1 (A-kinase anchor inhibitor 1)

Identity

Alias_namesC18orf42
chromosome 18 open reading frame 42
A kinase (PRKA) anchor inhibitor 1
Other alias
HGNC (Hugo) AKAIN1
LocusID (NCBI) 642597
Atlas_Id 78553
Location 18p11.31  [Link to chromosome band 18p11]
Location_base_pair Starts at 5143673 and ends at 5197256 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AKAIN1   28285
Cards
Entrez_Gene (NCBI)AKAIN1  642597  A-kinase anchor inhibitor 1
AliasesC18orf42
GeneCards (Weizmann)AKAIN1
Ensembl hg19 (Hinxton)ENSG00000231824 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000231824 [Gene_View]  chr18:5143673-5197256 [Contig_View]  AKAIN1 [Vega]
ICGC DataPortalENSG00000231824
TCGA cBioPortalAKAIN1
AceView (NCBI)AKAIN1
Genatlas (Paris)AKAIN1
WikiGenes642597
SOURCE (Princeton)AKAIN1
Genetics Home Reference (NIH)AKAIN1
Genomic and cartography
GoldenPath hg38 (UCSC)AKAIN1  -     chr18:5143673-5197256 -  18p11.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AKAIN1  -     18p11.31   [Description]    (hg19-Feb_2009)
EnsemblAKAIN1 - 18p11.31 [CytoView hg19]  AKAIN1 - 18p11.31 [CytoView hg38]
Mapping of homologs : NCBIAKAIN1 [Mapview hg19]  AKAIN1 [Mapview hg38]
OMIM616427   
Gene and transcription
Genbank (Entrez)AI681285 EL953233 HY128307
RefSeq transcript (Entrez)NM_001145194 NM_001330553
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AKAIN1
Cluster EST : UnigeneHs.437160 [ NCBI ]
CGAP (NCI)Hs.437160
Alternative Splicing GalleryENSG00000231824
Gene ExpressionAKAIN1 [ NCBI-GEO ]   AKAIN1 [ EBI - ARRAY_EXPRESS ]   AKAIN1 [ SEEK ]   AKAIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)AKAIN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)642597
GTEX Portal (Tissue expression)AKAIN1
Human Protein AtlasENSG00000231824-AKAIN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0CW23   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0CW23  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0CW23
Splice isoforms : SwissVarP0CW23
PhosPhoSitePlusP0CW23
Domains : Interpro (EBI)AKAP7_RI-RII-bd_dom   
Domain families : Pfam (Sanger)AKAP7_RIRII_bdg (PF10470)   
Domain families : Pfam (NCBI)pfam10470   
Conserved Domain (NCBI)AKAIN1
DMDM Disease mutations642597
Blocks (Seattle)AKAIN1
SuperfamilyP0CW23
Human Protein Atlas [tissue]ENSG00000231824-AKAIN1 [tissue]
Peptide AtlasP0CW23
IPIIPI00644582   
Protein Interaction databases
DIP (DOE-UCLA)P0CW23
IntAct (EBI)P0CW23
FunCoupENSG00000231824
BioGRIDAKAIN1
STRING (EMBL)AKAIN1
ZODIACAKAIN1
Ontologies - Pathways
QuickGOP0CW23
Ontology : AmiGOcytosol  protein localization  regulation of protein kinase A signaling  protein kinase A regulatory subunit binding  protein kinase A binding  
Ontology : EGO-EBIcytosol  protein localization  regulation of protein kinase A signaling  protein kinase A regulatory subunit binding  protein kinase A binding  
NDEx NetworkAKAIN1
Atlas of Cancer Signalling NetworkAKAIN1
Wikipedia pathwaysAKAIN1
Orthology - Evolution
OrthoDB642597
GeneTree (enSembl)ENSG00000231824
Phylogenetic Trees/Animal Genes : TreeFamAKAIN1
HOVERGENP0CW23
HOGENOMP0CW23
Homologs : HomoloGeneAKAIN1
Homology/Alignments : Family Browser (UCSC)AKAIN1
Gene fusions - Rearrangements
Fusion: Tumor Portal AKAIN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAKAIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AKAIN1
dbVarAKAIN1
ClinVarAKAIN1
1000_GenomesAKAIN1 
Exome Variant ServerAKAIN1
ExAC (Exome Aggregation Consortium)ENSG00000231824
GNOMAD BrowserENSG00000231824
Genetic variants : HAPMAP642597
Genomic Variants (DGV)AKAIN1 [DGVbeta]
DECIPHERAKAIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAKAIN1 
Mutations
ICGC Data PortalAKAIN1 
TCGA Data PortalAKAIN1 
Broad Tumor PortalAKAIN1
OASIS PortalAKAIN1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDAKAIN1
BioMutasearch AKAIN1
DgiDB (Drug Gene Interaction Database)AKAIN1
DoCM (Curated mutations)AKAIN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AKAIN1 (select a term)
intoGenAKAIN1
Cancer3DAKAIN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616427   
Orphanet
MedgenAKAIN1
Genetic Testing Registry AKAIN1
NextProtP0CW23 [Medical]
TSGene642597
GENETestsAKAIN1
Target ValidationAKAIN1
Huge Navigator AKAIN1 [HugePedia]
snp3D : Map Gene to Disease642597
BioCentury BCIQAKAIN1
ClinGenAKAIN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD642597
Chemical/Pharm GKB GenePA166048983
Clinical trialAKAIN1
Miscellaneous
canSAR (ICR)AKAIN1 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAKAIN1
EVEXAKAIN1
GoPubMedAKAIN1
iHOPAKAIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:37:22 CET 2017

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