AKAP13 (A kinase (PRKA) anchor protein 13)

Identity

Other names	AKAP-Lbc
	BRX
	FLJ11952
	FLJ43341
	HA-3
	Ht31
	LBC
	PROTO-LB
	PROTO-LBC
	c-lbc
Hugo	AKAP13
Location	15q24-q25
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	AKAP13
GDB	AKAP13
Entrez_Gene	AKAP13  11214  A kinase (PRKA) anchor protein 13
	Cards
GeneCards	AKAP13
Ensembl	AKAP13 [Search_View]   ENSG00000170776 [Gene_View]
Genatlas	AKAP13
GeneLynx	AKAP13
eGenome	AKAP13
euGene	11214
	Genomic and cartography
GoldenPath	AKAP13  -     chr15:83724875-84093590 +  15q25.3   [Description]    (hg18-March_2006)
Ensembl	AKAP13 - 15q25.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	AKAP13
	Gene and transcription
Genbank	AB055890 [ ENTREZ ]
Genbank	AB209414 [ ENTREZ ]
Genbank	AF086293 [ ENTREZ ]
Genbank	AF126008 [ ENTREZ ]
Genbank	AF387101 [ ENTREZ ]
RefSeq	NM_006738 [ SRS ]    NM_006738 [ ENTREZ ]
RefSeq	NM_007200 [ SRS ]    NM_007200 [ ENTREZ ]
RefSeq	NM_144767 [ SRS ]    NM_144767 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010274 [ SRS ]    NT_010274 [ ENTREZ ]
RefSeq	NW_001838222 [ SRS ]    NW_001838222 [ ENTREZ ]
RefSeq	NW_925940 [ SRS ]    NW_925940 [ ENTREZ ]
AceView	AKAP13 AceView - NCBI
Unigene	Hs.710656 [ SRS ]    Hs.710656 [ NCBI ]     HS710656 [ spliceNest ]
Fast-db	9788 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q12802 [ SRS]    Q12802 [ EXPASY ]     Q12802 [ INTERPRO ]
Prosite	PS00741 DH_1 [ SRS ]    PS00741 DH_1 [ Expasy ]
Prosite	PS50010 DH_2 [ SRS ]    PS50010 DH_2 [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR000219 DH-domain [ SRS ]    IPR000219 DH-domain [ EBI ]
Interpro	IPR001331 GDS_CDC24_CS [ SRS ]    IPR001331 GDS_CDC24_CS [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR015721 RhoGEF_like [ SRS ]    IPR015721 RhoGEF_like [ EBI ]
CluSTr	Q12802
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00621 RhoGEF [ SRS ]    PF00621 RhoGEF [ Sanger ]    pfam00621 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00233 PH [EMBL]
Smart	SM00325 RhoGEF [EMBL]
Blocks	Q12802
PDB	AKAP13 [ SRS ]    AKAP13 [ PdbSum ],   AKAP13 [ IMB ]   AKAP13 [ RSDB ]
HPRD	05253
	Protein Interaction databases
DIP	Q12802
IntAct	Q12802
	Polymorphism : SNP, mutations, diseases
OMIM	604686    [ map ]
GENECLINICS	604686
SNP	AKAP13 [dbSNP-NCBI]
SNP	NM_006738 [SNP-NCI]
SNP	NM_007200 [SNP-NCI]
SNP	NM_144767 [SNP-NCI]
SNP	AKAP13 [GeneSNPs - Utah]  AKAP13] [HGBASE - SRS]
HAPMAP	AKAP13 [HAPMAP]
COSMIC	AKAP13 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	AKAP13
	General knowledge
Family Browser	AKAP13 [UCSC Family Browser]
SOURCE	NM_006738
SOURCE	NM_007200
SOURCE	NM_144767
SMD	Hs.710656
SAGE	Hs.710656
GO	cAMP-dependent protein kinase activity [Amigo]  cAMP-dependent protein kinase activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	receptor activity [Amigo]  receptor activity
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	Rho guanyl-nucleotide exchange factor activity [Amigo]  Rho guanyl-nucleotide exchange factor activity
GO	protein binding [Amigo]  protein binding
GO	cellular_component [Amigo]  cellular_component
GO	intracellular [Amigo]  intracellular
GO	membrane fraction [Amigo]  membrane fraction
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	biological_process [Amigo]  biological_process
GO	zinc ion binding [Amigo]  zinc ion binding
GO	membrane [Amigo]  membrane
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	regulation of Rho protein signal transduction [Amigo]  regulation of Rho protein signal transduction
GO	metal ion binding [Amigo]  metal ion binding
BIOCARTA	Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation    [Genes]
PubGene	AKAP13
TreeFam	AKAP13
CTD	11214 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	AKAP13 Related clones (RZPD - Berlin)
	PubMed
PubMed	37 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 14 16:57:10 2008