Identity
HGNC
LOCATION
Xp11.22
LOCUSID
ALIAS
AKAP 82,AKAP-4,AKAP82,CT99,FSC1,HI,PRKA4,hAKAP82,p82
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8852
MIM: 300185
HGNC: 374
Ensembl: ENSG00000147081
Variants:
dbSNP: 8852
ClinVar: 8852
TCGA: ENSG00000147081
COSMIC: AKAP4
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35253625 | 2022 | Silencing of A-kinase anchor protein 4 inhibits the metastasis and growth of non-small cell lung cancer. | 2 |
| 35967402 | 2022 | Identification of CD8(+) T-cell epitope from multiple myeloma-specific antigen AKAP4. | 1 |
| 35253625 | 2022 | Silencing of A-kinase anchor protein 4 inhibits the metastasis and growth of non-small cell lung cancer. | 2 |
| 35967402 | 2022 | Identification of CD8(+) T-cell epitope from multiple myeloma-specific antigen AKAP4. | 1 |
| 34409659 | 2021 | A new hemizygous missense mutation, c.454T＞C (p.S152P), in AKAP4 gene is associated with asthenozoospermia. | 2 |
| 34415320 | 2021 | Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development. | 14 |
| 34409659 | 2021 | A new hemizygous missense mutation, c.454T＞C (p.S152P), in AKAP4 gene is associated with asthenozoospermia. | 2 |
| 34415320 | 2021 | Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development. | 14 |
| 32342732 | 2020 | Knockdown of A-kinase anchor protein 4 inhibits proliferation of triple-negative breast cancer cells in vitro and in vivo. | 4 |
| 32342732 | 2020 | Knockdown of A-kinase anchor protein 4 inhibits proliferation of triple-negative breast cancer cells in vitro and in vivo. | 4 |
| 29480665 | 2018 | AKAP4, SPAG9 and NY-ESO-1 in Iranian Colorectal Cancer Patients as Probable Diagnostic and Prognostic Biomarkers. | 8 |
| 29581387 | 2018 | RNASET2 impairs the sperm motility via PKA/PI3K/calcium signal pathways. | 9 |
| 29984477 | 2018 | A-kinase anchor protein 4 precursor (pro-AKAP4) in human spermatozoa. | 15 |
| 30145836 | 2018 | Knockdown of A-kinase anchor protein 4 inhibits hypoxia-induced epithelial-to-mesenchymal transition via suppression of the Wnt/β-catenin pathway in human gastric cancer cells. | 3 |
| 30545223 | 2018 | Down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes by Lactobacillus rhamnosus GG and Lactobacillus crispatus SJ-3C-US supernatants in HeLa cell line. | 0 |
Citation
Dessen P
AKAP4 (A-kinase anchoring protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46741/akap4
