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AKAP5 (A-kinase anchoring protein 5)

Identity

Alias_namesA kinase (PRKA) anchor protein 5
Alias_symbol (synonym)AKAP75
AKAP79
Other aliasH21
HGNC (Hugo) AKAP5
LocusID (NCBI) 9495
Atlas_Id 47463
Location 14q23.3  [Link to chromosome band 14q23]
Location_base_pair Starts at 64465499 and ends at 64474503 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AKAP5   375
Cards
Entrez_Gene (NCBI)AKAP5  9495  A-kinase anchoring protein 5
AliasesAKAP75; AKAP79; H21
GeneCards (Weizmann)AKAP5
Ensembl hg19 (Hinxton)ENSG00000179841 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179841 [Gene_View]  chr14:64465499-64474503 [Contig_View]  AKAP5 [Vega]
ICGC DataPortalENSG00000179841
TCGA cBioPortalAKAP5
AceView (NCBI)AKAP5
Genatlas (Paris)AKAP5
WikiGenes9495
SOURCE (Princeton)AKAP5
Genetics Home Reference (NIH)AKAP5
Genomic and cartography
GoldenPath hg38 (UCSC)AKAP5  -     chr14:64465499-64474503 +  14q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AKAP5  -     14q23.3   [Description]    (hg19-Feb_2009)
EnsemblAKAP5 - 14q23.3 [CytoView hg19]  AKAP5 - 14q23.3 [CytoView hg38]
Mapping of homologs : NCBIAKAP5 [Mapview hg19]  AKAP5 [Mapview hg38]
OMIM604688   
Gene and transcription
Genbank (Entrez)AK124004 AK315336 BC057229 BC131516 DA942424
RefSeq transcript (Entrez)NM_004857
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AKAP5
Cluster EST : UnigeneHs.656683 [ NCBI ]
CGAP (NCI)Hs.656683
Alternative Splicing GalleryENSG00000179841
Gene ExpressionAKAP5 [ NCBI-GEO ]   AKAP5 [ EBI - ARRAY_EXPRESS ]   AKAP5 [ SEEK ]   AKAP5 [ MEM ]
Gene Expression Viewer (FireBrowse)AKAP5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9495
GTEX Portal (Tissue expression)AKAP5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24588   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24588  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24588
Splice isoforms : SwissVarP24588
PhosPhoSitePlusP24588
Domains : Interpro (EBI)Pkinase-A_anch_WSK-motif   
Domain families : Pfam (Sanger)WSK (PF03832)   
Domain families : Pfam (NCBI)pfam03832   
Conserved Domain (NCBI)AKAP5
DMDM Disease mutations9495
Blocks (Seattle)AKAP5
PDB (SRS)2H9R    3LL8   
PDB (PDBSum)2H9R    3LL8   
PDB (IMB)2H9R    3LL8   
PDB (RSDB)2H9R    3LL8   
Structural Biology KnowledgeBase2H9R    3LL8   
SCOP (Structural Classification of Proteins)2H9R    3LL8   
CATH (Classification of proteins structures)2H9R    3LL8   
SuperfamilyP24588
Human Protein AtlasENSG00000179841
Peptide AtlasP24588
HPRD05255
IPIIPI00307794   
Protein Interaction databases
DIP (DOE-UCLA)P24588
IntAct (EBI)P24588
FunCoupENSG00000179841
BioGRIDAKAP5
STRING (EMBL)AKAP5
ZODIACAKAP5
Ontologies - Pathways
QuickGOP24588
Ontology : AmiGOprotein binding  calmodulin binding  cytosol  plasma membrane  protein targeting  signal transduction  chemical synaptic transmission  adenylate cyclase binding  positive regulation of protein kinase A signaling  positive regulation of cAMP biosynthetic process  protein kinase A regulatory subunit binding  protein kinase A binding  
Ontology : EGO-EBIprotein binding  calmodulin binding  cytosol  plasma membrane  protein targeting  signal transduction  chemical synaptic transmission  adenylate cyclase binding  positive regulation of protein kinase A signaling  positive regulation of cAMP biosynthetic process  protein kinase A regulatory subunit binding  protein kinase A binding  
NDEx NetworkAKAP5
Atlas of Cancer Signalling NetworkAKAP5
Wikipedia pathwaysAKAP5
Orthology - Evolution
OrthoDB9495
GeneTree (enSembl)ENSG00000179841
Phylogenetic Trees/Animal Genes : TreeFamAKAP5
HOVERGENP24588
HOGENOMP24588
Homologs : HomoloGeneAKAP5
Homology/Alignments : Family Browser (UCSC)AKAP5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAKAP5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AKAP5
dbVarAKAP5
ClinVarAKAP5
1000_GenomesAKAP5 
Exome Variant ServerAKAP5
ExAC (Exome Aggregation Consortium)AKAP5 (select the gene name)
Genetic variants : HAPMAP9495
Genomic Variants (DGV)AKAP5 [DGVbeta]
DECIPHERAKAP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAKAP5 
Mutations
ICGC Data PortalAKAP5 
TCGA Data PortalAKAP5 
Broad Tumor PortalAKAP5
OASIS PortalAKAP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAKAP5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAKAP5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AKAP5
DgiDB (Drug Gene Interaction Database)AKAP5
DoCM (Curated mutations)AKAP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AKAP5 (select a term)
intoGenAKAP5
Cancer3DAKAP5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604688   
Orphanet
MedgenAKAP5
Genetic Testing Registry AKAP5
NextProtP24588 [Medical]
TSGene9495
GENETestsAKAP5
Target ValidationAKAP5
Huge Navigator AKAP5 [HugePedia]
snp3D : Map Gene to Disease9495
BioCentury BCIQAKAP5
ClinGenAKAP5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9495
Chemical/Pharm GKB GenePA24669
Clinical trialAKAP5
Miscellaneous
canSAR (ICR)AKAP5 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAKAP5
EVEXAKAP5
GoPubMedAKAP5
iHOPAKAP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:56:47 CEST 2017

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