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AKIRIN1 (akirin 1)

Identity

Alias (NCBI)C1orf108
STRF2
HGNC (Hugo) AKIRIN1
HGNC Alias symbFLJ12666
HGNC Previous nameC1orf108
HGNC Previous namechromosome 1 open reading frame 108
LocusID (NCBI) 79647
Atlas_Id 57604
Location 1p34.3  [Link to chromosome band 1p34]
Location_base_pair Starts at 38991276 and ends at 39006059 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AD_1 () / AKIRIN1 (1p34.3)AKIRIN1 (1p34.3) / AKIRIN1 (1p34.3)AKIRIN1 (1p34.3) / MEAF6 (1p34.3)
AKIRIN1 (1p34.3) / PPIE (1p34.2)AKIRIN1 (1p34.3) / RAB21 (12q21.1)AKIRIN1 (1p34.3) / SORBS1 (10q24.1)
LIFR (5p13.1) / AKIRIN1 (1p34.3)MACF1 (1p34.3) / AKIRIN1 (1p34.3)OPHN1 (Xq12) / AKIRIN1 (1p34.3)
PSMC3 (11p11.2) / AKIRIN1 (1p34.3)SLC12A2 (5q23.3) / AKIRIN1 (1p34.3)YWHAQ (2p25.1) / AKIRIN1 (1p34.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AKIRIN1   25744
Cards
Entrez_Gene (NCBI)AKIRIN1    akirin 1
AliasesC1orf108; STRF2
GeneCards (Weizmann)AKIRIN1
Ensembl hg19 (Hinxton)ENSG00000174574 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174574 [Gene_View]  ENSG00000174574 [Sequence]  chr1:38991276-39006059 [Contig_View]  AKIRIN1 [Vega]
ICGC DataPortalENSG00000174574
TCGA cBioPortalAKIRIN1
AceView (NCBI)AKIRIN1
Genatlas (Paris)AKIRIN1
SOURCE (Princeton)AKIRIN1
Genetics Home Reference (NIH)AKIRIN1
Genomic and cartography
GoldenPath hg38 (UCSC)AKIRIN1  -     chr1:38991276-39006059 +  1p34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AKIRIN1  -     1p34.3   [Description]    (hg19-Feb_2009)
GoldenPathAKIRIN1 - 1p34.3 [CytoView hg19]  AKIRIN1 - 1p34.3 [CytoView hg38]
ImmunoBaseENSG00000174574
Genome Data Viewer NCBIAKIRIN1 [Mapview hg19]  
OMIM615164   
Gene and transcription
Genbank (Entrez)AK022728 AK092624 AK124799 AK126262 AK223276
RefSeq transcript (Entrez)NM_001136275 NM_024595
Consensus coding sequences : CCDS (NCBI)AKIRIN1
Gene ExpressionAKIRIN1 [ NCBI-GEO ]   AKIRIN1 [ EBI - ARRAY_EXPRESS ]   AKIRIN1 [ SEEK ]   AKIRIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)AKIRIN1 [ Firebrowse - Broad ]
GenevisibleExpression of AKIRIN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79647
GTEX Portal (Tissue expression)AKIRIN1
Human Protein AtlasENSG00000174574-AKIRIN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H9L7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H9L7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H9L7
PhosPhoSitePlusQ9H9L7
Domains : Interpro (EBI)Akirin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)AKIRIN1
SuperfamilyQ9H9L7
AlphaFold pdb e-kbQ9H9L7   
Human Protein Atlas [tissue]ENSG00000174574-AKIRIN1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9H9L7
IntAct (EBI)Q9H9L7
BioGRIDAKIRIN1
STRING (EMBL)AKIRIN1
ZODIACAKIRIN1
Ontologies - Pathways
QuickGOQ9H9L7
Ontology : AmiGOchromatin  transcription coregulator activity  protein binding  nucleus  nucleus  nucleoplasm  positive regulation of lamellipodium assembly  positive regulation of lamellipodium assembly  positive regulation of macrophage chemotaxis  positive regulation of macrophage chemotaxis  myoblast migration involved in skeletal muscle regeneration  myoblast migration involved in skeletal muscle regeneration  nuclear membrane  positive regulation of myoblast differentiation  positive regulation of myoblast differentiation  positive regulation of transcription by RNA polymerase II  negative regulation of skeletal muscle satellite cell proliferation  negative regulation of skeletal muscle satellite cell proliferation  negative regulation of satellite cell differentiation  
Ontology : EGO-EBIchromatin  transcription coregulator activity  protein binding  nucleus  nucleus  nucleoplasm  positive regulation of lamellipodium assembly  positive regulation of lamellipodium assembly  positive regulation of macrophage chemotaxis  positive regulation of macrophage chemotaxis  myoblast migration involved in skeletal muscle regeneration  myoblast migration involved in skeletal muscle regeneration  nuclear membrane  positive regulation of myoblast differentiation  positive regulation of myoblast differentiation  positive regulation of transcription by RNA polymerase II  negative regulation of skeletal muscle satellite cell proliferation  negative regulation of skeletal muscle satellite cell proliferation  negative regulation of satellite cell differentiation  
NDEx NetworkAKIRIN1
Atlas of Cancer Signalling NetworkAKIRIN1
Wikipedia pathwaysAKIRIN1
Orthology - Evolution
OrthoDB79647
GeneTree (enSembl)ENSG00000174574
Phylogenetic Trees/Animal Genes : TreeFamAKIRIN1
Homologs : HomoloGeneAKIRIN1
Homology/Alignments : Family Browser (UCSC)AKIRIN1
Gene fusions - Rearrangements
Fusion : QuiverAKIRIN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAKIRIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AKIRIN1
dbVarAKIRIN1
ClinVarAKIRIN1
MonarchAKIRIN1
1000_GenomesAKIRIN1 
Exome Variant ServerAKIRIN1
GNOMAD BrowserENSG00000174574
Varsome BrowserAKIRIN1
ACMGAKIRIN1 variants
VarityQ9H9L7
Genomic Variants (DGV)AKIRIN1 [DGVbeta]
DECIPHERAKIRIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAKIRIN1 
Mutations
ICGC Data PortalAKIRIN1 
TCGA Data PortalAKIRIN1 
Broad Tumor PortalAKIRIN1
OASIS PortalAKIRIN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAKIRIN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAKIRIN1
Mutations and Diseases : HGMDAKIRIN1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAKIRIN1
DgiDB (Drug Gene Interaction Database)AKIRIN1
DoCM (Curated mutations)AKIRIN1
CIViC (Clinical Interpretations of Variants in Cancer)AKIRIN1
Cancer3DAKIRIN1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615164   
Orphanet
DisGeNETAKIRIN1
MedgenAKIRIN1
Genetic Testing Registry AKIRIN1
NextProtQ9H9L7 [Medical]
GENETestsAKIRIN1
Target ValidationAKIRIN1
Huge Navigator AKIRIN1 [HugePedia]
ClinGenAKIRIN1
Clinical trials, drugs, therapy
MyCancerGenomeAKIRIN1
Protein Interactions : CTDAKIRIN1
Pharm GKB GenePA162376180
PharosQ9H9L7
Clinical trialAKIRIN1
Miscellaneous
canSAR (ICR)AKIRIN1
HarmonizomeAKIRIN1
DataMed IndexAKIRIN1
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAKIRIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 14:59:00 CEST 2021

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