Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AKIRIN2 (akirin 2)

Identity

Alias_namesC6orf166
chromosome 6 open reading frame 166
Alias_symbol (synonym)FLJ10342
dJ486L4.2
Other aliasFBI1
HGNC (Hugo) AKIRIN2
LocusID (NCBI) 55122
Atlas_Id 56346
Location 6q15  [Link to chromosome band 6q15]
Location_base_pair Starts at 87674860 and ends at 87702267 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKIRIN2 (6q15) / ANKRD55 (5q11.2)AKIRIN2 (6q15) / CTNNA3 (10q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;6)(q11;q15) AKIRIN2/ANKRD55


External links

Nomenclature
HGNC (Hugo)AKIRIN2   21407
Cards
Entrez_Gene (NCBI)AKIRIN2  55122  akirin 2
AliasesC6orf166; FBI1; dJ486L4.2
GeneCards (Weizmann)AKIRIN2
Ensembl hg19 (Hinxton)ENSG00000135334 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135334 [Gene_View]  ENSG00000135334 [Sequence]  chr6:87674860-87702267 [Contig_View]  AKIRIN2 [Vega]
ICGC DataPortalENSG00000135334
TCGA cBioPortalAKIRIN2
AceView (NCBI)AKIRIN2
Genatlas (Paris)AKIRIN2
WikiGenes55122
SOURCE (Princeton)AKIRIN2
Genetics Home Reference (NIH)AKIRIN2
Genomic and cartography
GoldenPath hg38 (UCSC)AKIRIN2  -     chr6:87674860-87702267 -  6q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AKIRIN2  -     6q15   [Description]    (hg19-Feb_2009)
EnsemblAKIRIN2 - 6q15 [CytoView hg19]  AKIRIN2 - 6q15 [CytoView hg38]
Mapping of homologs : NCBIAKIRIN2 [Mapview hg19]  AKIRIN2 [Mapview hg38]
OMIM615165   
Gene and transcription
Genbank (Entrez)AK001204 AK222701 BC000764 BC003042 BC005051
RefSeq transcript (Entrez)NM_018064
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AKIRIN2
Cluster EST : UnigeneHs.485915 [ NCBI ]
CGAP (NCI)Hs.485915
Alternative Splicing GalleryENSG00000135334
Gene ExpressionAKIRIN2 [ NCBI-GEO ]   AKIRIN2 [ EBI - ARRAY_EXPRESS ]   AKIRIN2 [ SEEK ]   AKIRIN2 [ MEM ]
Gene Expression Viewer (FireBrowse)AKIRIN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55122
GTEX Portal (Tissue expression)AKIRIN2
Human Protein AtlasENSG00000135334-AKIRIN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53H80   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53H80  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53H80
Splice isoforms : SwissVarQ53H80
PhosPhoSitePlusQ53H80
Domains : Interpro (EBI)Akirin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)AKIRIN2
DMDM Disease mutations55122
Blocks (Seattle)AKIRIN2
SuperfamilyQ53H80
Human Protein Atlas [tissue]ENSG00000135334-AKIRIN2 [tissue]
Peptide AtlasQ53H80
HPRD12864
IPIIPI00604547   
Protein Interaction databases
DIP (DOE-UCLA)Q53H80
IntAct (EBI)Q53H80
FunCoupENSG00000135334
BioGRIDAKIRIN2
STRING (EMBL)AKIRIN2
ZODIACAKIRIN2
Ontologies - Pathways
QuickGOQ53H80
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  positive regulation of cell proliferation  embryo development ending in birth or egg hatching  positive regulation of endopeptidase activity  transcriptional repressor complex  enzyme binding  response to lipopolysaccharide  positive regulation of interleukin-6 production  innate immune response  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  positive regulation of cell proliferation  embryo development ending in birth or egg hatching  positive regulation of endopeptidase activity  transcriptional repressor complex  enzyme binding  response to lipopolysaccharide  positive regulation of interleukin-6 production  innate immune response  positive regulation of transcription by RNA polymerase II  
NDEx NetworkAKIRIN2
Atlas of Cancer Signalling NetworkAKIRIN2
Wikipedia pathwaysAKIRIN2
Orthology - Evolution
OrthoDB55122
GeneTree (enSembl)ENSG00000135334
Phylogenetic Trees/Animal Genes : TreeFamAKIRIN2
HOVERGENQ53H80
HOGENOMQ53H80
Homologs : HomoloGeneAKIRIN2
Homology/Alignments : Family Browser (UCSC)AKIRIN2
Gene fusions - Rearrangements
Fusion : QuiverAKIRIN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAKIRIN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AKIRIN2
dbVarAKIRIN2
ClinVarAKIRIN2
1000_GenomesAKIRIN2 
Exome Variant ServerAKIRIN2
ExAC (Exome Aggregation Consortium)ENSG00000135334
GNOMAD BrowserENSG00000135334
Genetic variants : HAPMAP55122
Genomic Variants (DGV)AKIRIN2 [DGVbeta]
DECIPHERAKIRIN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAKIRIN2 
Mutations
ICGC Data PortalAKIRIN2 
TCGA Data PortalAKIRIN2 
Broad Tumor PortalAKIRIN2
OASIS PortalAKIRIN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAKIRIN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAKIRIN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AKIRIN2
DgiDB (Drug Gene Interaction Database)AKIRIN2
DoCM (Curated mutations)AKIRIN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AKIRIN2 (select a term)
intoGenAKIRIN2
Cancer3DAKIRIN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615165   
Orphanet
DisGeNETAKIRIN2
MedgenAKIRIN2
Genetic Testing Registry AKIRIN2
NextProtQ53H80 [Medical]
TSGene55122
GENETestsAKIRIN2
Target ValidationAKIRIN2
Huge Navigator AKIRIN2 [HugePedia]
snp3D : Map Gene to Disease55122
BioCentury BCIQAKIRIN2
ClinGenAKIRIN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55122
Chemical/Pharm GKB GenePA162376195
Clinical trialAKIRIN2
Miscellaneous
canSAR (ICR)AKIRIN2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAKIRIN2
EVEXAKIRIN2
GoPubMedAKIRIN2
iHOPAKIRIN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:13:39 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.