Atlas of Genetics and Cytogenetics in Oncology and Haematology


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AKR1B15 (aldo-keto reductase family 1 member B15)

Identity

Other aliasAKR1B10L
AKR1B10L, AK1R1B7
AKR1R1B7
HGNC (Hugo) AKR1B15
LocusID (NCBI) 441282
Atlas_Id 60230
Location 7q33  [Link to chromosome band 7q33]
Location_base_pair Starts at 134549097 and ends at 134579840 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CALD1 (7q33) / AKR1B15 (7q33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AKR1B15   37281
Cards
Entrez_Gene (NCBI)AKR1B15  441282  aldo-keto reductase family 1 member B15
AliasesAKR1B10L; AKR1B10L,; AKR1R1B7
GeneCards (Weizmann)AKR1B15
Ensembl hg19 (Hinxton)ENSG00000227471 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000227471 [Gene_View]  chr7:134549097-134579840 [Contig_View]  AKR1B15 [Vega]
ICGC DataPortalENSG00000227471
TCGA cBioPortalAKR1B15
AceView (NCBI)AKR1B15
Genatlas (Paris)AKR1B15
WikiGenes441282
SOURCE (Princeton)AKR1B15
Genetics Home Reference (NIH)AKR1B15
Genomic and cartography
GoldenPath hg38 (UCSC)AKR1B15  -     chr7:134549097-134579840 +  7q33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AKR1B15  -     7q33   [Description]    (hg19-Feb_2009)
EnsemblAKR1B15 - 7q33 [CytoView hg19]  AKR1B15 - 7q33 [CytoView hg38]
Mapping of homologs : NCBIAKR1B15 [Mapview hg19]  AKR1B15 [Mapview hg38]
OMIM616336   
Gene and transcription
Genbank (Entrez)BC072676 BX335355
RefSeq transcript (Entrez)NM_001080538
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AKR1B15
Cluster EST : UnigeneHs.729418 [ NCBI ]
CGAP (NCI)Hs.729418
Alternative Splicing GalleryENSG00000227471
Gene ExpressionAKR1B15 [ NCBI-GEO ]   AKR1B15 [ EBI - ARRAY_EXPRESS ]   AKR1B15 [ SEEK ]   AKR1B15 [ MEM ]
Gene Expression Viewer (FireBrowse)AKR1B15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)441282
GTEX Portal (Tissue expression)AKR1B15
Protein : pattern, domain, 3D structure
UniProt/SwissProtC9JRZ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtC9JRZ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProC9JRZ8
Splice isoforms : SwissVarC9JRZ8
PhosPhoSitePlusC9JRZ8
Domaine pattern : Prosite (Expaxy)ALDOKETO_REDUCTASE_2 (PS00062)   
Domains : Interpro (EBI)Aldo/ket_reductase_CS    Aldo/keto_reductase    NADP_OxRdtase_dom   
Domain families : Pfam (Sanger)Aldo_ket_red (PF00248)   
Domain families : Pfam (NCBI)pfam00248   
Conserved Domain (NCBI)AKR1B15
DMDM Disease mutations441282
Blocks (Seattle)AKR1B15
SuperfamilyC9JRZ8
Human Protein AtlasENSG00000227471
Peptide AtlasC9JRZ8
IPIIPI00925567   IPI01010749   IPI00942692   
Protein Interaction databases
DIP (DOE-UCLA)C9JRZ8
IntAct (EBI)C9JRZ8
FunCoupENSG00000227471
BioGRIDAKR1B15
STRING (EMBL)AKR1B15
ZODIACAKR1B15
Ontologies - Pathways
QuickGOC9JRZ8
Ontology : AmiGOestradiol 17-beta-dehydrogenase activity  mitochondrial matrix  cytosol  estrogen biosynthetic process  oxidation-reduction process  
Ontology : EGO-EBIestradiol 17-beta-dehydrogenase activity  mitochondrial matrix  cytosol  estrogen biosynthetic process  oxidation-reduction process  
NDEx NetworkAKR1B15
Atlas of Cancer Signalling NetworkAKR1B15
Wikipedia pathwaysAKR1B15
Orthology - Evolution
OrthoDB441282
GeneTree (enSembl)ENSG00000227471
Phylogenetic Trees/Animal Genes : TreeFamAKR1B15
HOVERGENC9JRZ8
HOGENOMC9JRZ8
Homologs : HomoloGeneAKR1B15
Homology/Alignments : Family Browser (UCSC)AKR1B15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAKR1B15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AKR1B15
dbVarAKR1B15
ClinVarAKR1B15
1000_GenomesAKR1B15 
Exome Variant ServerAKR1B15
ExAC (Exome Aggregation Consortium)AKR1B15 (select the gene name)
Genetic variants : HAPMAP441282
Genomic Variants (DGV)AKR1B15 [DGVbeta]
DECIPHERAKR1B15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAKR1B15 
Mutations
ICGC Data PortalAKR1B15 
TCGA Data PortalAKR1B15 
Broad Tumor PortalAKR1B15
OASIS PortalAKR1B15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAKR1B15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAKR1B15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AKR1B15
DgiDB (Drug Gene Interaction Database)AKR1B15
DoCM (Curated mutations)AKR1B15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AKR1B15 (select a term)
intoGenAKR1B15
Cancer3DAKR1B15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616336   
Orphanet
MedgenAKR1B15
Genetic Testing Registry AKR1B15
NextProtC9JRZ8 [Medical]
TSGene441282
GENETestsAKR1B15
Target ValidationAKR1B15
Huge Navigator AKR1B15 [HugePedia]
snp3D : Map Gene to Disease441282
BioCentury BCIQAKR1B15
ClinGenAKR1B15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD441282
Chemical/Pharm GKB GenePA165617622
Clinical trialAKR1B15
Miscellaneous
canSAR (ICR)AKR1B15 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAKR1B15
EVEXAKR1B15
GoPubMedAKR1B15
iHOPAKR1B15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:37:49 CEST 2017

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