Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))

Identity

Alias_namesaldo-keto reductase family 7-like
Alias_symbol (synonym)AFAR3
Other aliasAFB1-AR 3
AFB1-AR3
AKR7A4
HGNC (Hugo) AKR7L
LocusID (NCBI) 246181
Atlas_Id 60236
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 19265982 and ends at 19274122 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AKR7L   24056
Cards
Entrez_Gene (NCBI)AKR7L  246181  aldo-keto reductase family 7 like (gene/pseudogene)
AliasesAFAR3; AFB1-AR; AFB1-AR3; AKR7A4
GeneCards (Weizmann)AKR7L
Ensembl hg19 (Hinxton)ENSG00000211454 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000211454 [Gene_View]  chr1:19265982-19274122 [Contig_View]  AKR7L [Vega]
ICGC DataPortalENSG00000211454
TCGA cBioPortalAKR7L
AceView (NCBI)AKR7L
Genatlas (Paris)AKR7L
WikiGenes246181
SOURCE (Princeton)AKR7L
Genetics Home Reference (NIH)AKR7L
Genomic and cartography
GoldenPath hg38 (UCSC)AKR7L  -     chr1:19265982-19274122 -  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AKR7L  -     1p36.13   [Description]    (hg19-Feb_2009)
EnsemblAKR7L - 1p36.13 [CytoView hg19]  AKR7L - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBIAKR7L [Mapview hg19]  AKR7L [Mapview hg38]
OMIM608478   
Gene and transcription
Genbank (Entrez)AJ278012 BC035351 BQ083526 BX281656 CN359627
RefSeq transcript (Entrez)NM_001145289 NM_001348421
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AKR7L
Cluster EST : UnigeneHs.662342 [ NCBI ]
CGAP (NCI)Hs.662342
Alternative Splicing GalleryENSG00000211454
Gene ExpressionAKR7L [ NCBI-GEO ]   AKR7L [ EBI - ARRAY_EXPRESS ]   AKR7L [ SEEK ]   AKR7L [ MEM ]
Gene Expression Viewer (FireBrowse)AKR7L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246181
GTEX Portal (Tissue expression)AKR7L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHP1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHP1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHP1
Splice isoforms : SwissVarQ8NHP1
Catalytic activity : Enzyme1.-.-.- [ Enzyme-Expasy ]   1.-.-.-1.-.-.- [ IntEnz-EBI ]   1.-.-.- [ BRENDA ]   1.-.-.- [ KEGG ]   
PhosPhoSitePlusQ8NHP1
Domains : Interpro (EBI)NADP_OxRdtase_dom   
Domain families : Pfam (Sanger)Aldo_ket_red (PF00248)   
Domain families : Pfam (NCBI)pfam00248   
Conserved Domain (NCBI)AKR7L
DMDM Disease mutations246181
Blocks (Seattle)AKR7L
SuperfamilyQ8NHP1
Human Protein AtlasENSG00000211454
Peptide AtlasQ8NHP1
HPRD12240
IPIIPI00169280   IPI00397461   IPI00922851   IPI00942126   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHP1
IntAct (EBI)Q8NHP1
FunCoupENSG00000211454
BioGRIDAKR7L
STRING (EMBL)AKR7L
ZODIACAKR7L
Ontologies - Pathways
QuickGOQ8NHP1
Ontology : AmiGOaldo-keto reductase (NADP) activity  cytosol  xenobiotic metabolic process  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBIaldo-keto reductase (NADP) activity  cytosol  xenobiotic metabolic process  oxidation-reduction process  extracellular exosome  
NDEx NetworkAKR7L
Atlas of Cancer Signalling NetworkAKR7L
Wikipedia pathwaysAKR7L
Orthology - Evolution
OrthoDB246181
GeneTree (enSembl)ENSG00000211454
Phylogenetic Trees/Animal Genes : TreeFamAKR7L
HOVERGENQ8NHP1
HOGENOMQ8NHP1
Homologs : HomoloGeneAKR7L
Homology/Alignments : Family Browser (UCSC)AKR7L
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAKR7L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AKR7L
dbVarAKR7L
ClinVarAKR7L
1000_GenomesAKR7L 
Exome Variant ServerAKR7L
ExAC (Exome Aggregation Consortium)AKR7L (select the gene name)
Genetic variants : HAPMAP246181
Genomic Variants (DGV)AKR7L [DGVbeta]
DECIPHERAKR7L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAKR7L 
Mutations
ICGC Data PortalAKR7L 
TCGA Data PortalAKR7L 
Broad Tumor PortalAKR7L
OASIS PortalAKR7L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAKR7L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAKR7L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AKR7L
DgiDB (Drug Gene Interaction Database)AKR7L
DoCM (Curated mutations)AKR7L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AKR7L (select a term)
intoGenAKR7L
Cancer3DAKR7L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608478   
Orphanet
MedgenAKR7L
Genetic Testing Registry AKR7L
NextProtQ8NHP1 [Medical]
TSGene246181
GENETestsAKR7L
Target ValidationAKR7L
Huge Navigator AKR7L [HugePedia]
snp3D : Map Gene to Disease246181
BioCentury BCIQAKR7L
ClinGenAKR7L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD246181
Chemical/Pharm GKB GenePA164715300
Clinical trialAKR7L
Miscellaneous
canSAR (ICR)AKR7L (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAKR7L
EVEXAKR7L
GoPubMedAKR7L
iHOPAKR7L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:01:08 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.