Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AKT1S1 (AKT1 substrate 1 (proline-rich))

Identity

Other namesLobe
PRAS40
HGNC (Hugo) AKT1S1
LocusID (NCBI) 84335
Location 19q13.33
Location_base_pair Starts at 50372290 and ends at 50380644 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)AKT1S1   28426
Cards
Entrez_Gene (NCBI)AKT1S1  84335  AKT1 substrate 1 (proline-rich)
GeneCards (Weizmann)AKT1S1
Ensembl (Hinxton)ENSG00000204673 [Gene_View]  chr19:50372290-50380644 [Contig_View]  AKT1S1 [Vega]
ICGC DataPortalENSG00000204673
cBioPortalAKT1S1
AceView (NCBI)AKT1S1
Genatlas (Paris)AKT1S1
WikiGenes84335
SOURCE (Princeton)NM_001098632 NM_001098633 NM_001278159 NM_001278160 NM_032375
Genomic and cartography
GoldenPath (UCSC)AKT1S1  -  19q13.33   chr19:50372290-50380644 -  19q13.33   [Description]    (hg19-Feb_2009)
EnsemblAKT1S1 - 19q13.33 [CytoView]
Mapping of homologs : NCBIAKT1S1 [Mapview]
OMIM610221   
Gene and transcription
Genbank (Entrez)AK055511 AK092610 AK123687 AK226004 AK316603
RefSeq transcript (Entrez)NM_001098632 NM_001098633 NM_001278159 NM_001278160 NM_032375
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004929415
Consensus coding sequences : CCDS (NCBI)AKT1S1
Cluster EST : UnigeneHs.610819 [ NCBI ]
CGAP (NCI)Hs.610819
Alternative Splicing : Fast-db (Paris)GSHG0033340
Alternative Splicing GalleryENSG00000204673
Gene ExpressionAKT1S1 [ NCBI-GEO ]     AKT1S1 [ SEEK ]   AKT1S1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B36 (Uniprot)
NextProtQ96B36  [Medical]
With graphics : InterProQ96B36
Splice isoforms : SwissVarQ96B36 (Swissvar)
Domains : Interpro (EBI)AKT1S1 [organisation]  
Related proteins : CluSTrQ96B36
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations84335
Blocks (Seattle)Q96B36
Human Protein AtlasENSG00000204673 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ96B36
HPRD12441
IPIIPI00549786   IPI00306195   IPI00853601   
Protein Interaction databases
DIP (DOE-UCLA)Q96B36
IntAct (EBI)Q96B36
FunCoupENSG00000204673
BioGRIDAKT1S1
InParanoidQ96B36
Interologous Interaction database Q96B36
IntegromeDBAKT1S1
STRING (EMBL)AKT1S1
Ontologies - Pathways
Ontology : AmiGOprotein binding  nucleus  cytoplasm  cytosol  cytosol  negative regulation of protein kinase activity  epidermal growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  TORC1 complex  negative regulation of TOR signaling  Fc-epsilon receptor signaling pathway  regulation of neuron apoptotic process  innate immune response  negative regulation of cell size  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  cytosol  cytosol  negative regulation of protein kinase activity  epidermal growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  TORC1 complex  negative regulation of TOR signaling  Fc-epsilon receptor signaling pathway  regulation of neuron apoptotic process  innate immune response  negative regulation of cell size  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  
Pathways : KEGGmTOR signaling pathway   
Protein Interaction DatabaseAKT1S1
Wikipedia pathwaysAKT1S1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)AKT1S1
snp3D : Map Gene to Disease84335
SNP (GeneSNP Utah)AKT1S1
SNP : HGBaseAKT1S1
Genetic variants : HAPMAPAKT1S1
Exome VariantAKT1S1
1000_GenomesAKT1S1 
ICGC programENSG00000204673 
Somatic Mutations in Cancer : COSMICAKT1S1 
CONAN: Copy Number AnalysisAKT1S1 
Mutations and Diseases : HGMDAKT1S1
Mutations and Diseases : intOGenAKT1S1
Genomic VariantsAKT1S1  AKT1S1 [DGVbeta]
dbVarAKT1S1
ClinVarAKT1S1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM610221   
MedgenAKT1S1
GENETestsAKT1S1
Disease Genetic AssociationAKT1S1
Huge Navigator AKT1S1 [HugePedia]  AKT1S1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneAKT1S1
Homology/Alignments : Family Browser (UCSC)AKT1S1
Phylogenetic Trees/Animal Genes : TreeFamAKT1S1
Chemical/Protein Interactions : CTD84335
Chemical/Pharm GKB GenePA134943587
Clinical trialAKT1S1
Cancer Resource (Charite)ENSG00000204673
Other databases
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
CoreMineAKT1S1
iHOPAKT1S1
OncoSearchAKT1S1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:37:46 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.