Atlas of Genetics and Cytogenetics in Oncology and Haematology

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AKT1S1 (AKT1 substrate 1 (proline-rich))

Identity

Other namesLobe
PRAS40
HGNC (Hugo) AKT1S1
LocusID (NCBI) 84335
Location 19q13.33
Location_base_pair Starts at 50372297 and ends at 50380644 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)AKT1S1   28426
Entrez_Gene (NCBI)AKT1S1  84335  AKT1 substrate 1 (proline-rich)
Cards
GeneCards (Weizmann)AKT1S1
Ensembl (Hinxton)ENSG00000204673 [Gene_View]  chr19:50372297-50380644 [Contig_View]  AKT1S1 [Vega]
AceView (NCBI)AKT1S1
Genatlas (Paris)AKT1S1
SOURCE (Stanford)NM_001098632 NM_001098633 NM_032375
Genomic and cartography
GoldenPath (UCSC)AKT1S1  -  19q13.33   chr19:50372297-50380644 -  19q13.33   [Description]    (hg19-Feb_2009)
EnsemblAKT1S1 - 19q13.33 [CytoView]
Mapping of homologs : NCBIAKT1S1 [Mapview]
OMIM610221   
Gene and transcription
Genbank (Entrez)AK055511 AK092610 AK123687 AK226004 AK316603
RefSeq transcript (SRS)NM_001098632 NM_001098633 NM_032375
RefSeq transcript (Entrez)NM_001098632 NM_001098633 NM_032375
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004078099
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004078099
Consensus coding sequences : CCDS (NCBI)AKT1S1
Cluster EST : UnigeneHs.515542 [ SRS ] Hs.515542 [ NCBI ]
CGAP (NCI)Hs.515542
Alternative Splicing : Fast-db (Paris)GSHG0033340
Alternative Splicing GalleryENSG00000204673
Gene ExpressionAKT1S1 [ NCBI-GEO ]   AKT1S1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B36 (SRS) Q96B36 (Uniprot)
NextProtQ96B36
With graphics : InterProQ96B36
Splice isoforms : SwissVarQ96B36(Swissvar)
Domains : Interpro (SRS)AKT1S1   
Domains : Interpro (EBI)AKT1S1   
Related proteins : CluSTrQ96B36
Domain families : Pfam (SRS)
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM84335
Blocks (Seattle)Q96B36
Human Protein AtlasENSG00000204673
HPRD12441
IPIIPI00549786   IPI00306195   IPI00853601   
Protein Interaction databases
DIP (DOE-UCLA)Q96B36
IntAct (EBI)Q96B36
FunCoupENSG00000204673
REACTOMEAKT1S1
Protein Interaction Database84335
BioGRIDAKT1S1
InParanoidQ96B36
Interologous Interaction database Q96B36
IntegromeDBAKT1S1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)AKT1S1
SNP (GeneSNP Utah)AKT1S1
SNP : HGBaseAKT1S1
Genetic variants : HAPMAPAKT1S1
Somatic Mutations in Cancer : COSMICAKT1S1 
CONAN: Copy Number AnalysisAKT1S1 
Mutations and Diseases : HGMDAKT1S1
OMIM610221   
GENETests610221   
Disease Genetic AssociationAKT1S1
Huge Navigator AKT1S1 [HugePedia]  AKT1S1 [HugeCancerGEM]
Genomic VariantsAKT1S1  AKT1S1 [DGVbeta]
snp3D : Map Gene to Disease84335
General knowledge
Homologs : HomoloGeneAKT1S1
Homology/Alignments : Family Browser (UCSC)AKT1S1
Phylogenetic Trees/Animal Genes : TreeFamAKT1S1
Chemical/Protein Interactions : CTD84335
Chemical/Pharm GKB GenePA134943587
Clinical trialAKT1S1
Cancer Resource (Charite)ENSG00000204673
Ontology : AmiGOprotein binding  nucleus  cytosol  negative regulation of protein kinase activity  epidermal growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  TORC1 complex  negative regulation of TOR signaling cascade  regulation of neuron apoptotic process  cytosolic part  negative regulation of cell size  nerve growth factor receptor signaling pathway  phosphatidylinositol-mediated signaling  
Ontology : EGO-EBIprotein binding  nucleus  cytosol  negative regulation of protein kinase activity  epidermal growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  TORC1 complex  negative regulation of TOR signaling cascade  regulation of neuron apoptotic process  cytosolic part  negative regulation of cell size  nerve growth factor receptor signaling pathway  phosphatidylinositol-mediated signaling  
Other databases
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
PubGeneAKT1S1
iHOPAKT1S1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:33:52 CEST 2013
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