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ALB (albumin)

Identity

Other aliasANALBA
FDAH
PRO0883
PRO0903
PRO1341
HGNC (Hugo) ALB
LocusID (NCBI) 213
Atlas_Id 45575
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 74269972 and ends at 74287129 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABLIM3 (5q32) / ALB (4q13.3)ACTR3 (2q14.1) / ALB (4q13.3)AHSG (3q27.3) / ALB (4q13.3)
ALAS2 (Xp11.21) / ALB (4q13.3)ALB (4q13.3) / ALB (4q13.3)ALB (4q13.3) / APP (21q21.3)
ALB (4q13.3) / MALAT1 (11q13.1)ALB (4q13.3) / RPS4Y1 (Yp11.31)ALB (4q13.3) / SERPING1 (11q12.1)
ALB (4q13.3) / SETD4 (21q22.12)ALB (4q13.3) / SIAE (11q24.2)ALB (4q13.3) / TF (3q22.1)
ALB (4q13.3) / VPS13B (8q22.2)ALB (4q13.3) / ZDHHC2 (8p22)AOX1 (2q33.1) / ALB (4q13.3)
APOB (2p24.1) / ALB (4q13.3)ARID4B (1q42.3) / ALB (4q13.3)C3 (19p13.3) / ALB (4q13.3)
CMAS (12p12.1) / ALB (4q13.3)EBNA1BP2 (1p34.2) / ALB (4q13.3)GABPA (21q21.3) / ALB (4q13.3)
KNG1 (3q27.3) / ALB (4q13.3)MATR3 (5q31.2) / ALB (4q13.3)MSL3 (Xp22.2) / ALB (4q13.3)
MYO18A (17q11.2) / ALB (4q13.3)RABGAP1L (1q25.1) / ALB (4q13.3)SASH3 (Xq26.1) / ALB (4q13.3)
STK38L (12p11.23) / ALB (4q13.3)TF (3q22.1) / ALB (4q13.3)TXNL4B (16q22.2) / ALB (4q13.3)
ZNF536 (19q12) / ALB (4q13.3)ALB 4q13.3 / SIAE 11q24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Liver: Fibrolamellar carcinoma


External links

Nomenclature
HGNC (Hugo)ALB   399
Cards
Entrez_Gene (NCBI)ALB  213  albumin
AliasesANALBA; FDAH; PRO0883; PRO0903; 
PRO1341
GeneCards (Weizmann)ALB
Ensembl hg19 (Hinxton)ENSG00000163631 [Gene_View]  chr4:74269972-74287129 [Contig_View]  ALB [Vega]
Ensembl hg38 (Hinxton)ENSG00000163631 [Gene_View]  chr4:74269972-74287129 [Contig_View]  ALB [Vega]
ICGC DataPortalENSG00000163631
TCGA cBioPortalALB
AceView (NCBI)ALB
Genatlas (Paris)ALB
WikiGenes213
SOURCE (Princeton)ALB
Genetics Home Reference (NIH)ALB
Genomic and cartography
GoldenPath hg19 (UCSC)ALB  -     chr4:74269972-74287129 +  4q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ALB  -     4q13.3   [Description]    (hg38-Dec_2013)
EnsemblALB - 4q13.3 [CytoView hg19]  ALB - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBIALB [Mapview hg19]  ALB [Mapview hg38]
OMIM103600   615999   616000   
Gene and transcription
Genbank (Entrez)A06977 AF190168 AF542069 AK292755 AK298437
RefSeq transcript (Entrez)NM_000477
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_009291 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)ALB
Cluster EST : UnigeneHs.592379 [ NCBI ]
CGAP (NCI)Hs.592379
Alternative Splicing GalleryENSG00000163631
Gene ExpressionALB [ NCBI-GEO ]   ALB [ EBI - ARRAY_EXPRESS ]   ALB [ SEEK ]   ALB [ MEM ]
Gene Expression Viewer (FireBrowse)ALB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)213
GTEX Portal (Tissue expression)ALB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02768   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02768  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02768
Splice isoforms : SwissVarP02768
PhosPhoSitePlusP02768
Domaine pattern : Prosite (Expaxy)ALBUMIN_1 (PS00212)    ALBUMIN_2 (PS51438)   
Domains : Interpro (EBI)ALB/AFP/VDB    Serum_albumin-like    Serum_albumin/AFP/Afamin    Serum_albumin_CS    Serum_albumin_N   
Domain families : Pfam (Sanger)Serum_albumin (PF00273)   
Domain families : Pfam (NCBI)pfam00273   
Domain families : Smart (EMBL)ALBUMIN (SM00103)  
Conserved Domain (NCBI)ALB
DMDM Disease mutations213
Blocks (Seattle)ALB
PDB (SRS)1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
PDB (PDBSum)1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
PDB (IMB)1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
PDB (RSDB)1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
Structural Biology KnowledgeBase1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
SCOP (Structural Classification of Proteins)1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
CATH (Classification of proteins structures)1AO6    1BJ5    1BKE    1BM0    1E78    1E7A    1E7B    1E7C    1E7E    1E7F    1E7G    1E7H    1E7I    1GNI    1GNJ    1H9Z    1HA2    1HK1    1HK2    1HK3    1HK4    1HK5    1N5U    1O9X    1TF0    1UOR    1YSX    2BX8    2BXA    2BXB    2BXC    2BXD    2BXE    2BXF    2BXG    2BXH    2BXI    2BXK    2BXL    2BXM    2BXN    2BXO    2BXP    2BXQ    2ESG    2I2Z    2I30    2N0X    2VDB    2VUE    2VUF    2XSI    2XVQ    2XVU    2XVV    2XVW    2XW0    2XW1    2YDF    3A73    3B9L    3B9M    3CX9    3JQZ    3JRY    3LU6    3LU7    3LU8    3SQJ    3TDL    3UIV    4BKE    4E99    4EMX    4G03    4G04    4HGK    4HGM    4IW1    4IW2    4K2C    4K71    4L8U    4L9K    4L9Q    4LA0    4LB2    4LB9    4N0F    4N0U    4S1Y    4Z69   
SuperfamilyP02768
Human Protein AtlasENSG00000163631
Peptide AtlasP02768
HPRD00062
IPIIPI00745872   IPI00384697   IPI00022434   IPI00908876   IPI00816012   IPI00216773   IPI00878517   IPI00878282   IPI00953582   IPI00965074   IPI00965577   IPI00966829   IPI00965913   
Protein Interaction databases
DIP (DOE-UCLA)P02768
IntAct (EBI)P02768
FunCoupENSG00000163631
BioGRIDALB
STRING (EMBL)ALB
ZODIACALB
Ontologies - Pathways
QuickGOP02768
Ontology : AmiGOretina homeostasis  platelet degranulation  DNA binding  fatty acid binding  fatty acid binding  copper ion binding  protein binding  extracellular region  extracellular region  basement membrane  extracellular space  nucleus  endoplasmic reticulum  Golgi apparatus  transport  receptor-mediated endocytosis  response to nutrient  drug binding  drug binding  zinc ion binding  cellular response to starvation  response to organic substance  toxic substance binding  bile acid and bile salt transport  antioxidant activity  oxygen binding  hemolysis by symbiont of host erythrocytes  enzyme binding  pyridoxal phosphate binding  platelet alpha granule lumen  lipoprotein metabolic process  identical protein binding  negative regulation of apoptotic process  negative regulation of programmed cell death  myelin sheath  protein complex  sodium-independent organic anion transport  positive regulation of circadian sleep/wake cycle, non-REM sleep  response to mercury ion  chaperone binding  maintenance of mitochondrion location  extracellular exosome  response to platinum ion  blood microparticle  cellular oxidant detoxification  
Ontology : EGO-EBIretina homeostasis  platelet degranulation  DNA binding  fatty acid binding  fatty acid binding  copper ion binding  protein binding  extracellular region  extracellular region  basement membrane  extracellular space  nucleus  endoplasmic reticulum  Golgi apparatus  transport  receptor-mediated endocytosis  response to nutrient  drug binding  drug binding  zinc ion binding  cellular response to starvation  response to organic substance  toxic substance binding  bile acid and bile salt transport  antioxidant activity  oxygen binding  hemolysis by symbiont of host erythrocytes  enzyme binding  pyridoxal phosphate binding  platelet alpha granule lumen  lipoprotein metabolic process  identical protein binding  negative regulation of apoptotic process  negative regulation of programmed cell death  myelin sheath  protein complex  sodium-independent organic anion transport  positive regulation of circadian sleep/wake cycle, non-REM sleep  response to mercury ion  chaperone binding  maintenance of mitochondrion location  extracellular exosome  response to platinum ion  blood microparticle  cellular oxidant detoxification  
NDEx NetworkALB
Atlas of Cancer Signalling NetworkALB
Wikipedia pathwaysALB
Orthology - Evolution
OrthoDB213
GeneTree (enSembl)ENSG00000163631
Phylogenetic Trees/Animal Genes : TreeFamALB
HOVERGENP02768
HOGENOMP02768
Homologs : HomoloGeneALB
Homology/Alignments : Family Browser (UCSC)ALB
Gene fusions - Rearrangements
Fusion : MitelmanALB/SIAE [4q13.3/11q24.2]  
Fusion: TCGAALB 4q13.3 SIAE 11q24.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALB
dbVarALB
ClinVarALB
1000_GenomesALB 
Exome Variant ServerALB
ExAC (Exome Aggregation Consortium)ALB (select the gene name)
Genetic variants : HAPMAP213
Genomic Variants (DGV)ALB [DGVbeta]
DECIPHER (Syndromes)4:74269972-74287129  ENSG00000163631
CONAN: Copy Number AnalysisALB 
Mutations
ICGC Data PortalALB 
TCGA Data PortalALB 
Broad Tumor PortalALB
OASIS PortalALB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ALB
DgiDB (Drug Gene Interaction Database)ALB
DoCM (Curated mutations)ALB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALB (select a term)
intoGenALB
Cancer3DALB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103600    615999    616000   
Orphanet11736   
MedgenALB
Genetic Testing Registry ALB
NextProtP02768 [Medical]
TSGene213
GENETestsALB
Huge Navigator ALB [HugePedia]
snp3D : Map Gene to Disease213
BioCentury BCIQALB
ClinGenALB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD213
Chemical/Pharm GKB GenePA24690
Clinical trialALB
Miscellaneous
canSAR (ICR)ALB (select the gene name)
Probes
Litterature
PubMed423 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALB
EVEXALB
GoPubMedALB
iHOPALB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:52:07 CEST 2017

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