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ALDH1B1 (aldehyde dehydrogenase 1 family member B1)

Identity

Alias_namesALDH5
aldehyde dehydrogenase 1 family
Alias_symbol (synonym)ALDHX
Other alias
HGNC (Hugo) ALDH1B1
LocusID (NCBI) 219
Atlas_Id 53104
Location 9p13.1  [Link to chromosome band 9p13]
Location_base_pair Starts at 38392664 and ends at 38398665 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NDUFB7 (19p13.12) / ALDH1B1 (9p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ALDH1B1   407
Cards
Entrez_Gene (NCBI)ALDH1B1  219  aldehyde dehydrogenase 1 family member B1
AliasesALDH5; ALDHX
GeneCards (Weizmann)ALDH1B1
Ensembl hg19 (Hinxton)ENSG00000137124 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137124 [Gene_View]  chr9:38392664-38398665 [Contig_View]  ALDH1B1 [Vega]
ICGC DataPortalENSG00000137124
TCGA cBioPortalALDH1B1
AceView (NCBI)ALDH1B1
Genatlas (Paris)ALDH1B1
WikiGenes219
SOURCE (Princeton)ALDH1B1
Genetics Home Reference (NIH)ALDH1B1
Genomic and cartography
GoldenPath hg38 (UCSC)ALDH1B1  -     chr9:38392664-38398665 +  9p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ALDH1B1  -     9p13.1   [Description]    (hg19-Feb_2009)
EnsemblALDH1B1 - 9p13.1 [CytoView hg19]  ALDH1B1 - 9p13.1 [CytoView hg38]
Mapping of homologs : NCBIALDH1B1 [Mapview hg19]  ALDH1B1 [Mapview hg38]
OMIM100670   
Gene and transcription
Genbank (Entrez)AI803741 AK225950 AK297020 AK313344 BC001619
RefSeq transcript (Entrez)NM_000692
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ALDH1B1
Cluster EST : UnigeneHs.743532 [ NCBI ]
CGAP (NCI)Hs.743532
Alternative Splicing GalleryENSG00000137124
Gene ExpressionALDH1B1 [ NCBI-GEO ]   ALDH1B1 [ EBI - ARRAY_EXPRESS ]   ALDH1B1 [ SEEK ]   ALDH1B1 [ MEM ]
Gene Expression Viewer (FireBrowse)ALDH1B1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219
GTEX Portal (Tissue expression)ALDH1B1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30837   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30837  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30837
Splice isoforms : SwissVarP30837
Catalytic activity : Enzyme1.2.1.3 [ Enzyme-Expasy ]   1.2.1.31.2.1.3 [ IntEnz-EBI ]   1.2.1.3 [ BRENDA ]   1.2.1.3 [ KEGG ]   
PhosPhoSitePlusP30837
Domaine pattern : Prosite (Expaxy)ALDEHYDE_DEHYDR_CYS (PS00070)    ALDEHYDE_DEHYDR_GLU (PS00687)   
Domains : Interpro (EBI)Ald_DH/histidinol_DH    Ald_DH_C    Ald_DH_CS_CYS    Ald_DH_CS_GLU    Ald_DH_N    Aldehyde_DH_dom   
Domain families : Pfam (Sanger)Aldedh (PF00171)   
Domain families : Pfam (NCBI)pfam00171   
Conserved Domain (NCBI)ALDH1B1
DMDM Disease mutations219
Blocks (Seattle)ALDH1B1
SuperfamilyP30837
Human Protein AtlasENSG00000137124
Peptide AtlasP30837
HPRD00005
IPIIPI00103467   IPI01015077   
Protein Interaction databases
DIP (DOE-UCLA)P30837
IntAct (EBI)P30837
FunCoupENSG00000137124
BioGRIDALDH1B1
STRING (EMBL)ALDH1B1
ZODIACALDH1B1
Ontologies - Pathways
QuickGOP30837
Ontology : AmiGOaldehyde dehydrogenase (NAD) activity  aldehyde dehydrogenase (NAD) activity  nucleoplasm  mitochondrion  mitochondrial matrix  carbohydrate metabolic process  ethanol catabolic process  ethanol oxidation  intracellular membrane-bounded organelle  NAD binding  
Ontology : EGO-EBIaldehyde dehydrogenase (NAD) activity  aldehyde dehydrogenase (NAD) activity  nucleoplasm  mitochondrion  mitochondrial matrix  carbohydrate metabolic process  ethanol catabolic process  ethanol oxidation  intracellular membrane-bounded organelle  NAD binding  
Pathways : KEGG   
NDEx NetworkALDH1B1
Atlas of Cancer Signalling NetworkALDH1B1
Wikipedia pathwaysALDH1B1
Orthology - Evolution
OrthoDB219
GeneTree (enSembl)ENSG00000137124
Phylogenetic Trees/Animal Genes : TreeFamALDH1B1
HOVERGENP30837
HOGENOMP30837
Homologs : HomoloGeneALDH1B1
Homology/Alignments : Family Browser (UCSC)ALDH1B1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALDH1B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALDH1B1
dbVarALDH1B1
ClinVarALDH1B1
1000_GenomesALDH1B1 
Exome Variant ServerALDH1B1
ExAC (Exome Aggregation Consortium)ALDH1B1 (select the gene name)
Genetic variants : HAPMAP219
Genomic Variants (DGV)ALDH1B1 [DGVbeta]
DECIPHERALDH1B1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisALDH1B1 
Mutations
ICGC Data PortalALDH1B1 
TCGA Data PortalALDH1B1 
Broad Tumor PortalALDH1B1
OASIS PortalALDH1B1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALDH1B1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALDH1B1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ALDH1B1
DgiDB (Drug Gene Interaction Database)ALDH1B1
DoCM (Curated mutations)ALDH1B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALDH1B1 (select a term)
intoGenALDH1B1
Cancer3DALDH1B1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM100670   
Orphanet
MedgenALDH1B1
Genetic Testing Registry ALDH1B1
NextProtP30837 [Medical]
TSGene219
GENETestsALDH1B1
Huge Navigator ALDH1B1 [HugePedia]
snp3D : Map Gene to Disease219
BioCentury BCIQALDH1B1
ClinGenALDH1B1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD219
Chemical/Pharm GKB GenePA24695
Clinical trialALDH1B1
Miscellaneous
canSAR (ICR)ALDH1B1 (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALDH1B1
EVEXALDH1B1
GoPubMedALDH1B1
iHOPALDH1B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:05:39 CEST 2017

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