Identity
HGNC
LOCATION
17p11.2
LOCUSID
ALIAS
ALDH3,ALDHIII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 218
MIM: 100660
HGNC: 405
Ensembl: ENSG00000108602
Variants:
dbSNP: 218
ClinVar: 218
TCGA: ENSG00000108602
COSMIC: ALDH3A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443560 | Breast Neoplasms | Disease | ClinicalAnnotation | associated | PD | ||
| PA449165 | cyclophosphamide | Chemical | ClinicalAnnotation | associated | PD | ||
| PA449412 | doxorubicin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35188323 | 2023 | ALDH3A1 overexpression in OSCC inhibits inflammation via phospho-Ser727 at STAT3 in tumor-associated macrophages. | 2 |
| 37730658 | 2023 | Hypoxia-induced ALDH3A1 promotes the proliferation of non-small-cell lung cancer by regulating energy metabolism reprogramming. | 4 |
| 35188323 | 2023 | ALDH3A1 overexpression in OSCC inhibits inflammation via phospho-Ser727 at STAT3 in tumor-associated macrophages. | 2 |
| 37730658 | 2023 | Hypoxia-induced ALDH3A1 promotes the proliferation of non-small-cell lung cancer by regulating energy metabolism reprogramming. | 4 |
| 33596621 | 2021 | Association with Corneal Remodeling Related Genes, ALDH3A1, LOX, and SPARC Genes Variations in Korean Keratoconus Patients. | 4 |
| 33596621 | 2021 | Association with Corneal Remodeling Related Genes, ALDH3A1, LOX, and SPARC Genes Variations in Korean Keratoconus Patients. | 4 |
| 32006654 | 2020 | Aldehyde dehydrogenase 3A1 confers oxidative stress resistance accompanied by altered DNA damage response in human corneal epithelial cells. | 15 |
| 32297178 | 2020 | Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis. | 23 |
| 32006654 | 2020 | Aldehyde dehydrogenase 3A1 confers oxidative stress resistance accompanied by altered DNA damage response in human corneal epithelial cells. | 15 |
| 32297178 | 2020 | Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis. | 23 |
| 31138432 | 2019 | Aldehyde dehydrogenase isoforms and inflammatory cell populations are differentially expressed in term human placentas affected by intrauterine growth restriction. | 7 |
| 31705020 | 2019 | Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation. | 17 |
| 31138432 | 2019 | Aldehyde dehydrogenase isoforms and inflammatory cell populations are differentially expressed in term human placentas affected by intrauterine growth restriction. | 7 |
| 31705020 | 2019 | Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation. | 17 |
| 28526614 | 2017 | Human aldehyde dehydrogenase 3A1 (ALDH3A1) exhibits chaperone-like function. | 8 |
Citation
Dessen P
ALDH3A1 (aldehyde dehydrogenase 3 family member A1)
Atlas Genet Cytogenet Oncol Haematol. 2004-05-01
Online version: http://atlasgeneticsoncology.org/gene/374/aldh3a1
