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ALDH3B1 (aldehyde dehydrogenase 3 family, member B1)

Identity

Alias_namesALDH7
aldehyde dehydrogenase 3 family, member B1
Other aliasALDH4
HGNC (Hugo) ALDH3B1
LocusID (NCBI) 221
Atlas_Id 60242
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67777775 and ends at 67796749 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PI4K2A (10q24.2) / ALDH3B1 (11q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ALDH3B1   410
Cards
Entrez_Gene (NCBI)ALDH3B1  221  aldehyde dehydrogenase 3 family, member B1
AliasesALDH4; ALDH7
GeneCards (Weizmann)ALDH3B1
Ensembl hg19 (Hinxton)ENSG00000006534 [Gene_View]  chr11:67777775-67796749 [Contig_View]  ALDH3B1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000006534 [Gene_View]  chr11:67777775-67796749 [Contig_View]  ALDH3B1 [Vega]
ICGC DataPortalENSG00000006534
TCGA cBioPortalALDH3B1
AceView (NCBI)ALDH3B1
Genatlas (Paris)ALDH3B1
WikiGenes221
SOURCE (Princeton)ALDH3B1
Genetics Home Reference (NIH)ALDH3B1
Genomic and cartography
GoldenPath hg19 (UCSC)ALDH3B1  -     chr11:67777775-67796749 +  11q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ALDH3B1  -     11q13.2   [Description]    (hg38-Dec_2013)
EnsemblALDH3B1 - 11q13.2 [CytoView hg19]  ALDH3B1 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIALDH3B1 [Mapview hg19]  ALDH3B1 [Mapview hg38]
OMIM600466   
Gene and transcription
Genbank (Entrez)AB209651 AK092029 AK291505 BC002553 BC013584
RefSeq transcript (Entrez)NM_000694 NM_001030010 NM_001161473 NM_001290058 NM_001290059
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_012282 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)ALDH3B1
Cluster EST : UnigeneHs.523841 [ NCBI ]
CGAP (NCI)Hs.523841
Alternative Splicing GalleryENSG00000006534
Gene ExpressionALDH3B1 [ NCBI-GEO ]   ALDH3B1 [ EBI - ARRAY_EXPRESS ]   ALDH3B1 [ SEEK ]   ALDH3B1 [ MEM ]
Gene Expression Viewer (FireBrowse)ALDH3B1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221
GTEX Portal (Tissue expression)ALDH3B1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43353   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43353  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43353
Splice isoforms : SwissVarP43353
Catalytic activity : Enzyme1.2.1.5 [ Enzyme-Expasy ]   1.2.1.51.2.1.5 [ IntEnz-EBI ]   1.2.1.5 [ BRENDA ]   1.2.1.5 [ KEGG ]   
PhosPhoSitePlusP43353
Domaine pattern : Prosite (Expaxy)ALDEHYDE_DEHYDR_CYS (PS00070)    ALDEHYDE_DEHYDR_GLU (PS00687)   
Domains : Interpro (EBI)Ald_DH/histidinol_DH    Ald_DH_C    Ald_DH_CS_CYS    Ald_DH_CS_GLU    Ald_DH_N    Aldehyde_DH_dom    Aldehyde_DH_NAD(P)   
Domain families : Pfam (Sanger)Aldedh (PF00171)   
Domain families : Pfam (NCBI)pfam00171   
Conserved Domain (NCBI)ALDH3B1
DMDM Disease mutations221
Blocks (Seattle)ALDH3B1
SuperfamilyP43353
Human Protein AtlasENSG00000006534
Peptide AtlasP43353
HPRD02716
IPIIPI00018031   IPI00166751   IPI00555728   IPI00306044   
Protein Interaction databases
DIP (DOE-UCLA)P43353
IntAct (EBI)P43353
FunCoupENSG00000006534
BioGRIDALDH3B1
STRING (EMBL)ALDH3B1
ZODIACALDH3B1
Ontologies - Pathways
QuickGOP43353
Ontology : AmiGO3-chloroallyl aldehyde dehydrogenase activity  aldehyde dehydrogenase [NAD(P)+] activity  protein binding  cytoplasm  cytosol  plasma membrane  alcohol metabolic process  ethanol catabolic process  lipid metabolic process  vesicle  cellular response to oxidative stress  aldehyde catabolic process  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBI3-chloroallyl aldehyde dehydrogenase activity  aldehyde dehydrogenase [NAD(P)+] activity  protein binding  cytoplasm  cytosol  plasma membrane  alcohol metabolic process  ethanol catabolic process  lipid metabolic process  vesicle  cellular response to oxidative stress  aldehyde catabolic process  oxidation-reduction process  extracellular exosome  
Pathways : KEGGGlycolysis / Gluconeogenesis    Histidine metabolism    Tyrosine metabolism    Phenylalanine metabolism    beta-Alanine metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkALDH3B1
Atlas of Cancer Signalling NetworkALDH3B1
Wikipedia pathwaysALDH3B1
Orthology - Evolution
OrthoDB221
GeneTree (enSembl)ENSG00000006534
Phylogenetic Trees/Animal Genes : TreeFamALDH3B1
HOVERGENP43353
HOGENOMP43353
Homologs : HomoloGeneALDH3B1
Homology/Alignments : Family Browser (UCSC)ALDH3B1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALDH3B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALDH3B1
dbVarALDH3B1
ClinVarALDH3B1
1000_GenomesALDH3B1 
Exome Variant ServerALDH3B1
ExAC (Exome Aggregation Consortium)ALDH3B1 (select the gene name)
Genetic variants : HAPMAP221
Genomic Variants (DGV)ALDH3B1 [DGVbeta]
DECIPHER (Syndromes)11:67777775-67796749  ENSG00000006534
CONAN: Copy Number AnalysisALDH3B1 
Mutations
ICGC Data PortalALDH3B1 
TCGA Data PortalALDH3B1 
Broad Tumor PortalALDH3B1
OASIS PortalALDH3B1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDALDH3B1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ALDH3B1
DgiDB (Drug Gene Interaction Database)ALDH3B1
DoCM (Curated mutations)ALDH3B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALDH3B1 (select a term)
intoGenALDH3B1
Cancer3DALDH3B1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600466   
Orphanet
MedgenALDH3B1
Genetic Testing Registry ALDH3B1
NextProtP43353 [Medical]
TSGene221
GENETestsALDH3B1
Huge Navigator ALDH3B1 [HugePedia]
snp3D : Map Gene to Disease221
BioCentury BCIQALDH3B1
ClinGenALDH3B1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221
Chemical/Pharm GKB GenePA24699
Clinical trialALDH3B1
Miscellaneous
canSAR (ICR)ALDH3B1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALDH3B1
EVEXALDH3B1
GoPubMedALDH3B1
iHOPALDH3B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:04 CET 2017

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