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ALDH3B2 (aldehyde dehydrogenase 3 family member B2)

Identity

Alias_namesALDH8
aldehyde dehydrogenase 3 family
Other alias
HGNC (Hugo) ALDH3B2
LocusID (NCBI) 222
Atlas_Id 47286
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67429633 and ends at 67442102 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CST1 (20p11.21) / ALDH3B2 (11q13.2)KCNMB4 (12q15) / ALDH3B2 (11q13.2)TMEM135 (11q14.2) / ALDH3B2 (11q13.2)
KCNMB4 12q15 / ALDH3B2 11q13.2TMEM135 11q14.2 / ALDH3B2 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ALDH3B2   411
Cards
Entrez_Gene (NCBI)ALDH3B2  222  aldehyde dehydrogenase 3 family member B2
AliasesALDH8
GeneCards (Weizmann)ALDH3B2
Ensembl hg19 (Hinxton)ENSG00000132746 [Gene_View]  chr11:67429633-67442102 [Contig_View]  ALDH3B2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000132746 [Gene_View]  chr11:67429633-67442102 [Contig_View]  ALDH3B2 [Vega]
ICGC DataPortalENSG00000132746
TCGA cBioPortalALDH3B2
AceView (NCBI)ALDH3B2
Genatlas (Paris)ALDH3B2
WikiGenes222
SOURCE (Princeton)ALDH3B2
Genetics Home Reference (NIH)ALDH3B2
Genomic and cartography
GoldenPath hg19 (UCSC)ALDH3B2  -     chr11:67429633-67442102 -  11q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ALDH3B2  -     11q13.2   [Description]    (hg38-Dec_2013)
EnsemblALDH3B2 - 11q13.2 [CytoView hg19]  ALDH3B2 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIALDH3B2 [Mapview hg19]  ALDH3B2 [Mapview hg38]
OMIM601917   
Gene and transcription
Genbank (Entrez)AK092464 AK299956 AK309277 BC007685 BG009508
RefSeq transcript (Entrez)NM_000695 NM_001031615
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_012255 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)ALDH3B2
Cluster EST : UnigeneHs.87539 [ NCBI ]
CGAP (NCI)Hs.87539
Alternative Splicing GalleryENSG00000132746
Gene ExpressionALDH3B2 [ NCBI-GEO ]   ALDH3B2 [ EBI - ARRAY_EXPRESS ]   ALDH3B2 [ SEEK ]   ALDH3B2 [ MEM ]
Gene Expression Viewer (FireBrowse)ALDH3B2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222
GTEX Portal (Tissue expression)ALDH3B2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48448   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48448  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48448
Splice isoforms : SwissVarP48448
Catalytic activity : Enzyme1.2.1.5 [ Enzyme-Expasy ]   1.2.1.51.2.1.5 [ IntEnz-EBI ]   1.2.1.5 [ BRENDA ]   1.2.1.5 [ KEGG ]   
PhosPhoSitePlusP48448
Domaine pattern : Prosite (Expaxy)ALDEHYDE_DEHYDR_CYS (PS00070)    ALDEHYDE_DEHYDR_GLU (PS00687)   
Domains : Interpro (EBI)Ald_DH/histidinol_DH    Ald_DH_C    Ald_DH_CS_CYS    Ald_DH_CS_GLU    Ald_DH_N    Aldehyde_DH_dom   
Domain families : Pfam (Sanger)Aldedh (PF00171)   
Domain families : Pfam (NCBI)pfam00171   
Conserved Domain (NCBI)ALDH3B2
DMDM Disease mutations222
Blocks (Seattle)ALDH3B2
SuperfamilyP48448
Human Protein AtlasENSG00000132746
Peptide AtlasP48448
HPRD03559
IPIIPI00009744   IPI00983486   IPI00982813   IPI00984800   
Protein Interaction databases
DIP (DOE-UCLA)P48448
IntAct (EBI)P48448
FunCoupENSG00000132746
BioGRIDALDH3B2
STRING (EMBL)ALDH3B2
ZODIACALDH3B2
Ontologies - Pathways
QuickGOP48448
Ontology : AmiGO3-chloroallyl aldehyde dehydrogenase activity  aldehyde dehydrogenase (NAD) activity  aldehyde dehydrogenase [NAD(P)+] activity  lipid particle  alcohol metabolic process  ethanol catabolic process  lipid metabolic process  sphingolipid biosynthetic process  oxidation-reduction process  
Ontology : EGO-EBI3-chloroallyl aldehyde dehydrogenase activity  aldehyde dehydrogenase (NAD) activity  aldehyde dehydrogenase [NAD(P)+] activity  lipid particle  alcohol metabolic process  ethanol catabolic process  lipid metabolic process  sphingolipid biosynthetic process  oxidation-reduction process  
Pathways : KEGGGlycolysis / Gluconeogenesis    Histidine metabolism    Tyrosine metabolism    Phenylalanine metabolism    beta-Alanine metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkALDH3B2
Atlas of Cancer Signalling NetworkALDH3B2
Wikipedia pathwaysALDH3B2
Orthology - Evolution
OrthoDB222
GeneTree (enSembl)ENSG00000132746
Phylogenetic Trees/Animal Genes : TreeFamALDH3B2
HOVERGENP48448
HOGENOMP48448
Homologs : HomoloGeneALDH3B2
Homology/Alignments : Family Browser (UCSC)ALDH3B2
Gene fusions - Rearrangements
Fusion : MitelmanKCNMB4/ALDH3B2 [12q15/11q13.2]  [t(11;12)(q13;q15)]  
Fusion : MitelmanTMEM135/ALDH3B2 [11q14.2/11q13.2]  [t(11;11)(q13;q14)]  
Fusion: TCGAKCNMB4 12q15 ALDH3B2 11q13.2 LUAD
Fusion: TCGATMEM135 11q14.2 ALDH3B2 11q13.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALDH3B2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALDH3B2
dbVarALDH3B2
ClinVarALDH3B2
1000_GenomesALDH3B2 
Exome Variant ServerALDH3B2
ExAC (Exome Aggregation Consortium)ALDH3B2 (select the gene name)
Genetic variants : HAPMAP222
Genomic Variants (DGV)ALDH3B2 [DGVbeta]
DECIPHER (Syndromes)11:67429633-67442102  ENSG00000132746
CONAN: Copy Number AnalysisALDH3B2 
Mutations
ICGC Data PortalALDH3B2 
TCGA Data PortalALDH3B2 
Broad Tumor PortalALDH3B2
OASIS PortalALDH3B2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALDH3B2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALDH3B2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ALDH3B2
DgiDB (Drug Gene Interaction Database)ALDH3B2
DoCM (Curated mutations)ALDH3B2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALDH3B2 (select a term)
intoGenALDH3B2
Cancer3DALDH3B2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601917   
Orphanet
MedgenALDH3B2
Genetic Testing Registry ALDH3B2
NextProtP48448 [Medical]
TSGene222
GENETestsALDH3B2
Huge Navigator ALDH3B2 [HugePedia]
snp3D : Map Gene to Disease222
BioCentury BCIQALDH3B2
ClinGenALDH3B2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222
Chemical/Pharm GKB GenePA24700
Clinical trialALDH3B2
Miscellaneous
canSAR (ICR)ALDH3B2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALDH3B2
EVEXALDH3B2
GoPubMedALDH3B2
iHOPALDH3B2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:55:31 CET 2017

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