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ALDH3B2 (aldehyde dehydrogenase 3 family member B2)

Identity

Alias (NCBI)ALDH8
HGNC (Hugo) ALDH3B2
HGNC Alias namealdehyde dehydrogenase 8
 acetaldehyde dehydrogenase 8
HGNC Previous nameALDH8
HGNC Previous namealdehyde dehydrogenase 3 family, member B2
LocusID (NCBI) 222
Atlas_Id 47286
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67662162 and ends at 67674840 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CST1 (20p11.21) / ALDH3B2 (11q13.2)KCNMB4 (12q15) / ALDH3B2 (11q13.2)TMEM135 (11q14.2) / ALDH3B2 (11q13.2)
KCNMB4 12q15 / ALDH3B2 11q13.2TMEM135 11q14.2 / ALDH3B2 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ALDH3B2   411
Cards
Entrez_Gene (NCBI)ALDH3B2    aldehyde dehydrogenase 3 family member B2
AliasesALDH8
GeneCards (Weizmann)ALDH3B2
Ensembl hg19 (Hinxton)ENSG00000132746 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132746 [Gene_View]  ENSG00000132746 [Sequence]  chr11:67662162-67674840 [Contig_View]  ALDH3B2 [Vega]
ICGC DataPortalENSG00000132746
TCGA cBioPortalALDH3B2
AceView (NCBI)ALDH3B2
Genatlas (Paris)ALDH3B2
SOURCE (Princeton)ALDH3B2
Genetics Home Reference (NIH)ALDH3B2
Genomic and cartography
GoldenPath hg38 (UCSC)ALDH3B2  -     chr11:67662162-67674840 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ALDH3B2  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathALDH3B2 - 11q13.2 [CytoView hg19]  ALDH3B2 - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000132746
Genome Data Viewer NCBIALDH3B2 [Mapview hg19]  
OMIM601917   
Gene and transcription
Genbank (Entrez)AK092464 AK299956 AK309277 BC007685 BG009508
RefSeq transcript (Entrez)NM_000695 NM_001031615 NM_001354345 NM_001393400 NM_001393401 NM_001393402
Consensus coding sequences : CCDS (NCBI)ALDH3B2
Gene ExpressionALDH3B2 [ NCBI-GEO ]   ALDH3B2 [ EBI - ARRAY_EXPRESS ]   ALDH3B2 [ SEEK ]   ALDH3B2 [ MEM ]
Gene Expression Viewer (FireBrowse)ALDH3B2 [ Firebrowse - Broad ]
GenevisibleExpression of ALDH3B2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222
GTEX Portal (Tissue expression)ALDH3B2
Human Protein AtlasENSG00000132746-ALDH3B2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48448   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48448  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48448
PhosPhoSitePlusP48448
Domaine pattern : Prosite (Expaxy)ALDEHYDE_DEHYDR_CYS (PS00070)    ALDEHYDE_DEHYDR_GLU (PS00687)   
Domains : Interpro (EBI)Ald_DH/histidinol_DH    Ald_DH_C    Ald_DH_CS_CYS    Ald_DH_CS_GLU    Ald_DH_N    Aldehyde_DH_dom   
Domain families : Pfam (Sanger)Aldedh (PF00171)   
Domain families : Pfam (NCBI)pfam00171   
Conserved Domain (NCBI)ALDH3B2
SuperfamilyP48448
AlphaFold pdb e-kbP48448   
Human Protein Atlas [tissue]ENSG00000132746-ALDH3B2 [tissue]
HPRD03559
Protein Interaction databases
DIP (DOE-UCLA)P48448
IntAct (EBI)P48448
BioGRIDALDH3B2
STRING (EMBL)ALDH3B2
ZODIACALDH3B2
Ontologies - Pathways
QuickGOP48448
Ontology : AmiGO3-chloroallyl aldehyde dehydrogenase activity  aldehyde dehydrogenase (NAD+) activity  aldehyde dehydrogenase [NAD(P)+] activity  lipid droplet  alcohol metabolic process  ethanol catabolic process  lipid metabolic process  sphingolipid biosynthetic process  glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity  
Ontology : EGO-EBI3-chloroallyl aldehyde dehydrogenase activity  aldehyde dehydrogenase (NAD+) activity  aldehyde dehydrogenase [NAD(P)+] activity  lipid droplet  alcohol metabolic process  ethanol catabolic process  lipid metabolic process  sphingolipid biosynthetic process  glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity  
Pathways : KEGGGlycolysis / Gluconeogenesis    Histidine metabolism    Tyrosine metabolism    Phenylalanine metabolism    beta-Alanine metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkALDH3B2
Atlas of Cancer Signalling NetworkALDH3B2
Wikipedia pathwaysALDH3B2
Orthology - Evolution
OrthoDB222
GeneTree (enSembl)ENSG00000132746
Phylogenetic Trees/Animal Genes : TreeFamALDH3B2
Homologs : HomoloGeneALDH3B2
Homology/Alignments : Family Browser (UCSC)ALDH3B2
Gene fusions - Rearrangements
Fusion : MitelmanKCNMB4/ALDH3B2 [12q15/11q13.2]  
Fusion : MitelmanTMEM135/ALDH3B2 [11q14.2/11q13.2]  
Fusion : QuiverALDH3B2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALDH3B2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALDH3B2
dbVarALDH3B2
ClinVarALDH3B2
MonarchALDH3B2
1000_GenomesALDH3B2 
Exome Variant ServerALDH3B2
GNOMAD BrowserENSG00000132746
Varsome BrowserALDH3B2
ACMGALDH3B2 variants
VarityP48448
Genomic Variants (DGV)ALDH3B2 [DGVbeta]
DECIPHERALDH3B2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisALDH3B2 
Mutations
ICGC Data PortalALDH3B2 
TCGA Data PortalALDH3B2 
Broad Tumor PortalALDH3B2
OASIS PortalALDH3B2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALDH3B2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DALDH3B2
Mutations and Diseases : HGMDALDH3B2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaALDH3B2
DgiDB (Drug Gene Interaction Database)ALDH3B2
DoCM (Curated mutations)ALDH3B2
CIViC (Clinical Interpretations of Variants in Cancer)ALDH3B2
Cancer3DALDH3B2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601917   
Orphanet
DisGeNETALDH3B2
MedgenALDH3B2
Genetic Testing Registry ALDH3B2
NextProtP48448 [Medical]
GENETestsALDH3B2
Target ValidationALDH3B2
Huge Navigator ALDH3B2 [HugePedia]
ClinGenALDH3B2
Clinical trials, drugs, therapy
MyCancerGenomeALDH3B2
Protein Interactions : CTDALDH3B2
Pharm GKB GenePA24700
PharosP48448
Clinical trialALDH3B2
Miscellaneous
canSAR (ICR)ALDH3B2
HarmonizomeALDH3B2
DataMed IndexALDH3B2
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXALDH3B2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:04 CEST 2021

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