Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ALDH7A1 (aldehyde dehydrogenase 7 family, member A1)

Identity

Other namesATQ1
EPD
PDE
HGNC (Hugo) ALDH7A1
LocusID (NCBI) 501
Location 5q23.2
Location_base_pair Starts at 125877533 and ends at 125931082 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ALDH7A1   877
Cards
Entrez_Gene (NCBI)ALDH7A1  501  aldehyde dehydrogenase 7 family, member A1
GeneCards (Weizmann)ALDH7A1
Ensembl hg19 (Hinxton)ENSG00000164904 [Gene_View]  chr5:125877533-125931082 [Contig_View]  ALDH7A1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164904 [Gene_View]  chr5:125877533-125931082 [Contig_View]  ALDH7A1 [Vega]
ICGC DataPortalENSG00000164904
cBioPortalALDH7A1
AceView (NCBI)ALDH7A1
Genatlas (Paris)ALDH7A1
WikiGenes501
SOURCE (Princeton)ALDH7A1
Genomic and cartography
GoldenPath hg19 (UCSC)ALDH7A1  -     chr5:125877533-125931082 -  5q23.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ALDH7A1  -     5q23.2   [Description]    (hg38-Dec_2013)
EnsemblALDH7A1 - 5q23.2 [CytoView hg19]  ALDH7A1 - 5q23.2 [CytoView hg38]
Mapping of homologs : NCBIALDH7A1 [Mapview hg19]  ALDH7A1 [Mapview hg38]
OMIM107323   266100   
Gene and transcription
Genbank (Entrez)AI039375 AK021800 AK092507 AK123774 AK295526
RefSeq transcript (Entrez)NM_001182 NM_001201377 NM_001202404
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NG_008600 NT_034772 NW_001838952 NW_004929323
Consensus coding sequences : CCDS (NCBI)ALDH7A1
Cluster EST : UnigeneHs.483239 [ NCBI ]
CGAP (NCI)Hs.483239
Alternative Splicing : Fast-db (Paris)GSHG0025030
Alternative Splicing GalleryENSG00000164904
Gene ExpressionALDH7A1 [ NCBI-GEO ]     ALDH7A1 [ SEEK ]   ALDH7A1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49419 (Uniprot)
NextProtP49419  [Medical]
With graphics : InterProP49419
Splice isoforms : SwissVarP49419 (Swissvar)
Catalytic activity : Enzyme1.2.1.31 [ Enzyme-Expasy ]   1.2.1.311.2.1.31 [ IntEnz-EBI ]   1.2.1.31 [ BRENDA ]   1.2.1.31 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ALDEHYDE_DEHYDR_GLU (PS00687)   
Domains : Interpro (EBI)Ald_DH/histidinol_DH    Ald_DH_C    Ald_DH_CS_GLU    Ald_DH_N    Aldehyde_DH_dom   
Related proteins : CluSTrP49419
Domain families : Pfam (Sanger)Aldedh (PF00171)   
Domain families : Pfam (NCBI)pfam00171   
DMDM Disease mutations501
Blocks (Seattle)P49419
PDB (SRS)2J6L   
PDB (PDBSum)2J6L   
PDB (IMB)2J6L   
PDB (RSDB)2J6L   
Human Protein AtlasENSG00000164904
Peptide AtlasP49419
HPRD00124
IPIIPI00221234   IPI00936002   IPI00910420   IPI01022677   IPI01020665   IPI01021131   IPI00909694   IPI00917841   IPI00917139   
Protein Interaction databases
DIP (DOE-UCLA)P49419
IntAct (EBI)P49419
FunCoupENSG00000164904
BioGRIDALDH7A1
IntegromeDBALDH7A1
STRING (EMBL)ALDH7A1
Ontologies - Pathways
QuickGOP49419
Ontology : AmiGOaldehyde dehydrogenase (NAD) activity  L-aminoadipate-semialdehyde dehydrogenase activity  protein binding  nucleus  cytoplasm  mitochondrion  mitochondrial matrix  cytosol  cellular aldehyde metabolic process  lysine catabolic process  sensory perception of sound  betaine-aldehyde dehydrogenase activity  glycine betaine biosynthetic process from choline  cellular nitrogen compound metabolic process  small molecule metabolic process  oxidation-reduction process  extracellular vesicular exosome  
Ontology : EGO-EBIaldehyde dehydrogenase (NAD) activity  L-aminoadipate-semialdehyde dehydrogenase activity  protein binding  nucleus  cytoplasm  mitochondrion  mitochondrial matrix  cytosol  cellular aldehyde metabolic process  lysine catabolic process  sensory perception of sound  betaine-aldehyde dehydrogenase activity  glycine betaine biosynthetic process from choline  cellular nitrogen compound metabolic process  small molecule metabolic process  oxidation-reduction process  extracellular vesicular exosome  
Pathways : KEGGGlycolysis / Gluconeogenesis    Ascorbate and aldarate metabolism    Fatty acid degradation    Glycine, serine and threonine metabolism    Valine, leucine and isoleucine degradation    Lysine biosynthesis    Lysine degradation    Arginine and proline metabolism    Histidine metabolism    Tryptophan metabolism    beta-Alanine metabolism    Glycerolipid metabolism    Pyruvate metabolism    Propanoate metabolism   
Protein Interaction DatabaseALDH7A1
DoCM (Curated mutations)ALDH7A1
Wikipedia pathwaysALDH7A1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerALDH7A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALDH7A1
dbVarALDH7A1
ClinVarALDH7A1
1000_GenomesALDH7A1 
Exome Variant ServerALDH7A1
SNP (GeneSNP Utah)ALDH7A1
SNP : HGBaseALDH7A1
Genetic variants : HAPMAPALDH7A1
Genomic VariantsALDH7A1  ALDH7A1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000164904 
Somatic Mutations in Cancer : COSMICALDH7A1 
CONAN: Copy Number AnalysisALDH7A1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)5:125877533-125931082
Mutations and Diseases : HGMDALDH7A1
OMIM107323    266100   
MedgenALDH7A1
NextProtP49419 [Medical]
GENETestsALDH7A1
Disease Genetic AssociationALDH7A1
Huge Navigator ALDH7A1 [HugePedia]  ALDH7A1 [HugeCancerGEM]
snp3D : Map Gene to Disease501
DGIdb (Drug Gene Interaction db)ALDH7A1
General knowledge
Homologs : HomoloGeneALDH7A1
Homology/Alignments : Family Browser (UCSC)ALDH7A1
Phylogenetic Trees/Animal Genes : TreeFamALDH7A1
Chemical/Protein Interactions : CTD501
Chemical/Pharm GKB GenePA24704
Clinical trialALDH7A1
Cancer Resource (Charite)ENSG00000164904
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
CoreMineALDH7A1
GoPubMedALDH7A1
iHOPALDH7A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 20:05:16 CET 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.