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ALG10B (ALG10B, alpha-1,2-glucosyltransferase)

Identity

Alias_namesasparagine-linked glycosylation 10
Alias_symbol (synonym)KCR1
Other aliasALG10
HGNC (Hugo) ALG10B
LocusID (NCBI) 144245
Atlas_Id 54115
Location 12q12  [Link to chromosome band 12q12]
Location_base_pair Starts at 38316755 and ends at 38329726 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALG10B (12q12) / IGFBP6 (12q13.13)RPS4X (Xq13.1) / ALG10B (12q12)TAF4 (20q13.33) / ALG10B (12q12)
ALG10B 12q12 / IGFBP6 12q13.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ALG10B   31088
Cards
Entrez_Gene (NCBI)ALG10B  144245  ALG10B, alpha-1,2-glucosyltransferase
AliasesALG10; KCR1
GeneCards (Weizmann)ALG10B
Ensembl hg19 (Hinxton)ENSG00000175548 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175548 [Gene_View]  chr12:38316755-38329726 [Contig_View]  ALG10B [Vega]
ICGC DataPortalENSG00000175548
TCGA cBioPortalALG10B
AceView (NCBI)ALG10B
Genatlas (Paris)ALG10B
WikiGenes144245
SOURCE (Princeton)ALG10B
Genetics Home Reference (NIH)ALG10B
Genomic and cartography
GoldenPath hg38 (UCSC)ALG10B  -     chr12:38316755-38329726 +  12q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ALG10B  -     12q12   [Description]    (hg19-Feb_2009)
EnsemblALG10B - 12q12 [CytoView hg19]  ALG10B - 12q12 [CytoView hg38]
Mapping of homologs : NCBIALG10B [Mapview hg19]  ALG10B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK123102 AK307955 AL712776 AY845858 BC137413
RefSeq transcript (Entrez)NM_001013620 NM_001308340
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ALG10B
Cluster EST : UnigeneHs.259305 [ NCBI ]
CGAP (NCI)Hs.259305
Alternative Splicing GalleryENSG00000175548
Gene ExpressionALG10B [ NCBI-GEO ]   ALG10B [ EBI - ARRAY_EXPRESS ]   ALG10B [ SEEK ]   ALG10B [ MEM ]
Gene Expression Viewer (FireBrowse)ALG10B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)144245
GTEX Portal (Tissue expression)ALG10B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5I7T1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5I7T1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5I7T1
Splice isoforms : SwissVarQ5I7T1
PhosPhoSitePlusQ5I7T1
Domains : Interpro (EBI)Alg10   
Domain families : Pfam (Sanger)DIE2_ALG10 (PF04922)   
Domain families : Pfam (NCBI)pfam04922   
Conserved Domain (NCBI)ALG10B
DMDM Disease mutations144245
Blocks (Seattle)ALG10B
SuperfamilyQ5I7T1
Human Protein AtlasENSG00000175548
Peptide AtlasQ5I7T1
HPRD11923
IPIIPI00105827   IPI01022694   IPI01022824   
Protein Interaction databases
DIP (DOE-UCLA)Q5I7T1
IntAct (EBI)Q5I7T1
FunCoupENSG00000175548
BioGRIDALG10B
STRING (EMBL)ALG10B
ZODIACALG10B
Ontologies - Pathways
QuickGOQ5I7T1
Ontology : AmiGOdolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity  endoplasmic reticulum membrane  plasma membrane  protein glycosylation  dolichol-linked oligosaccharide biosynthetic process  integral component of membrane  
Ontology : EGO-EBIdolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity  endoplasmic reticulum membrane  plasma membrane  protein glycosylation  dolichol-linked oligosaccharide biosynthetic process  integral component of membrane  
Pathways : KEGGN-Glycan biosynthesis   
NDEx NetworkALG10B
Atlas of Cancer Signalling NetworkALG10B
Wikipedia pathwaysALG10B
Orthology - Evolution
OrthoDB144245
GeneTree (enSembl)ENSG00000175548
Phylogenetic Trees/Animal Genes : TreeFamALG10B
HOVERGENQ5I7T1
HOGENOMQ5I7T1
Homologs : HomoloGeneALG10B
Homology/Alignments : Family Browser (UCSC)ALG10B
Gene fusions - Rearrangements
Fusion : MitelmanALG10B/IGFBP6 [12q12/12q13.13]  
Fusion : MitelmanTAF4/ALG10B [20q13.33/12q12]  [t(12;20)(q12;q13)]  
Fusion: TCGAALG10B 12q12 IGFBP6 12q13.13 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALG10B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALG10B
dbVarALG10B
ClinVarALG10B
1000_GenomesALG10B 
Exome Variant ServerALG10B
ExAC (Exome Aggregation Consortium)ALG10B (select the gene name)
Genetic variants : HAPMAP144245
Genomic Variants (DGV)ALG10B [DGVbeta]
DECIPHERALG10B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisALG10B 
Mutations
ICGC Data PortalALG10B 
TCGA Data PortalALG10B 
Broad Tumor PortalALG10B
OASIS PortalALG10B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALG10B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALG10B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ALG10B
DgiDB (Drug Gene Interaction Database)ALG10B
DoCM (Curated mutations)ALG10B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALG10B (select a term)
intoGenALG10B
Cancer3DALG10B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenALG10B
Genetic Testing Registry ALG10B
NextProtQ5I7T1 [Medical]
TSGene144245
GENETestsALG10B
Huge Navigator ALG10B [HugePedia]
snp3D : Map Gene to Disease144245
BioCentury BCIQALG10B
ClinGenALG10B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD144245
Chemical/Pharm GKB GenePA134936082
Clinical trialALG10B
Miscellaneous
canSAR (ICR)ALG10B (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALG10B
EVEXALG10B
GoPubMedALG10B
iHOPALG10B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:05:42 CEST 2017

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