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ALG10B (ALG10 alpha-1,2-glucosyltransferase B)

Identity

Alias (NCBI)ALG10
KCR1
HGNC (Hugo) ALG10B
HGNC Alias symbKCR1
HGNC Alias namepotassium channel regulator 1
 dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase
HGNC Previous nameasparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)
LocusID (NCBI) 144245
Atlas_Id 54115
Location 12q12  [Link to chromosome band 12q12]
Location_base_pair Starts at 38316774 and ends at 38329721 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ALG10B (12q12) / IGFBP6 (12q13.13)RPS4X (Xq13.1) / ALG10B (12q12)TAF4 (20q13.33) / ALG10B (12q12)
ALG10B 12q12 / IGFBP6 12q13.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ALG10B   31088
Cards
Entrez_Gene (NCBI)ALG10B    ALG10 alpha-1,2-glucosyltransferase B
AliasesALG10; KCR1
GeneCards (Weizmann)ALG10B
Ensembl hg19 (Hinxton)ENSG00000175548 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175548 [Gene_View]  ENSG00000175548 [Sequence]  chr12:38316774-38329721 [Contig_View]  ALG10B [Vega]
ICGC DataPortalENSG00000175548
TCGA cBioPortalALG10B
AceView (NCBI)ALG10B
Genatlas (Paris)ALG10B
SOURCE (Princeton)ALG10B
Genetics Home Reference (NIH)ALG10B
Genomic and cartography
GoldenPath hg38 (UCSC)ALG10B  -     chr12:38316774-38329721 +  12q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ALG10B  -     12q12   [Description]    (hg19-Feb_2009)
GoldenPathALG10B - 12q12 [CytoView hg19]  ALG10B - 12q12 [CytoView hg38]
ImmunoBaseENSG00000175548
Genome Data Viewer NCBIALG10B [Mapview hg19]  
OMIM603313   613688   
Gene and transcription
Genbank (Entrez)AK123102 AK307955 AL712776 AY845858 BC137413
RefSeq transcript (Entrez)NM_001013620 NM_001308340
Consensus coding sequences : CCDS (NCBI)ALG10B
Gene ExpressionALG10B [ NCBI-GEO ]   ALG10B [ EBI - ARRAY_EXPRESS ]   ALG10B [ SEEK ]   ALG10B [ MEM ]
Gene Expression Viewer (FireBrowse)ALG10B [ Firebrowse - Broad ]
GenevisibleExpression of ALG10B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)144245
GTEX Portal (Tissue expression)ALG10B
Human Protein AtlasENSG00000175548-ALG10B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5I7T1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5I7T1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5I7T1
PhosPhoSitePlusQ5I7T1
Domains : Interpro (EBI)Alg10   
Domain families : Pfam (Sanger)DIE2_ALG10 (PF04922)   
Domain families : Pfam (NCBI)pfam04922   
Conserved Domain (NCBI)ALG10B
SuperfamilyQ5I7T1
AlphaFold pdb e-kbQ5I7T1   
Human Protein Atlas [tissue]ENSG00000175548-ALG10B [tissue]
HPRD11923
Protein Interaction databases
DIP (DOE-UCLA)Q5I7T1
IntAct (EBI)Q5I7T1
BioGRIDALG10B
STRING (EMBL)ALG10B
ZODIACALG10B
Ontologies - Pathways
QuickGOQ5I7T1
Ontology : AmiGOprotein binding  endoplasmic reticulum  endoplasmic reticulum  plasma membrane  protein glycosylation  protein N-linked glycosylation  dolichol-linked oligosaccharide biosynthetic process  integral component of membrane  transferase activity  positive regulation of protein glycosylation  dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity  positive regulation of inward rectifier potassium channel activity  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  endoplasmic reticulum  plasma membrane  protein glycosylation  protein N-linked glycosylation  dolichol-linked oligosaccharide biosynthetic process  integral component of membrane  transferase activity  positive regulation of protein glycosylation  dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity  positive regulation of inward rectifier potassium channel activity  
Pathways : KEGGN-Glycan biosynthesis   
NDEx NetworkALG10B
Atlas of Cancer Signalling NetworkALG10B
Wikipedia pathwaysALG10B
Orthology - Evolution
OrthoDB144245
GeneTree (enSembl)ENSG00000175548
Phylogenetic Trees/Animal Genes : TreeFamALG10B
Homologs : HomoloGeneALG10B
Homology/Alignments : Family Browser (UCSC)ALG10B
Gene fusions - Rearrangements
Fusion : MitelmanALG10B/IGFBP6 [12q12/12q13.13]  
Fusion : MitelmanTAF4/ALG10B [20q13.33/12q12]  
Fusion : QuiverALG10B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALG10B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALG10B
dbVarALG10B
ClinVarALG10B
MonarchALG10B
1000_GenomesALG10B 
Exome Variant ServerALG10B
GNOMAD BrowserENSG00000175548
Varsome BrowserALG10B
ACMGALG10B variants
VarityQ5I7T1
Genomic Variants (DGV)ALG10B [DGVbeta]
DECIPHERALG10B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisALG10B 
Mutations
ICGC Data PortalALG10B 
TCGA Data PortalALG10B 
Broad Tumor PortalALG10B
OASIS PortalALG10B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALG10B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DALG10B
Mutations and Diseases : HGMDALG10B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaALG10B
DgiDB (Drug Gene Interaction Database)ALG10B
DoCM (Curated mutations)ALG10B
CIViC (Clinical Interpretations of Variants in Cancer)ALG10B
Cancer3DALG10B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603313    613688   
Orphanet
DisGeNETALG10B
MedgenALG10B
Genetic Testing Registry ALG10B
NextProtQ5I7T1 [Medical]
GENETestsALG10B
Target ValidationALG10B
Huge Navigator ALG10B [HugePedia]
ClinGenALG10B
Clinical trials, drugs, therapy
MyCancerGenomeALG10B
Protein Interactions : CTDALG10B
Pharm GKB GenePA134936082
PharosQ5I7T1
Clinical trialALG10B
Miscellaneous
canSAR (ICR)ALG10B
HarmonizomeALG10B
DataMed IndexALG10B
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXALG10B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:06 CEST 2021

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