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ALG3 (ALG3, alpha-1,3- mannosyltransferase)

Identity

Alias_namesasparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase)
asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae)
Alias_symbol (synonym)NOT56L
Not56
CDGS4
D16Ertd36e
Other aliasCDG1D
CDGS6
not
HGNC (Hugo) ALG3
LocusID (NCBI) 10195
Atlas_Id 60254
Location 3q27.1  [Link to chromosome band 3q27]
Location_base_pair Starts at 183960117 and ends at 183967313 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACTL6A (3q26.33) / ALG3 (3q27.1)B3GNT5 (3q27.1) / ALG3 (3q27.1)ZACN (17q25.1) / ALG3 (3q27.1)
ACTL6A ALG3B3GNT5 ALG3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ALG3   23056
Cards
Entrez_Gene (NCBI)ALG3  10195  ALG3, alpha-1,3- mannosyltransferase
AliasesCDG1D; CDGS4; CDGS6; D16Ertd36e; 
NOT56L; Not56; not
GeneCards (Weizmann)ALG3
Ensembl hg19 (Hinxton)ENSG00000214160 [Gene_View]  chr3:183960117-183967313 [Contig_View]  ALG3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000214160 [Gene_View]  chr3:183960117-183967313 [Contig_View]  ALG3 [Vega]
ICGC DataPortalENSG00000214160
TCGA cBioPortalALG3
AceView (NCBI)ALG3
Genatlas (Paris)ALG3
WikiGenes10195
SOURCE (Princeton)ALG3
Genetics Home Reference (NIH)ALG3
Genomic and cartography
GoldenPath hg19 (UCSC)ALG3  -     chr3:183960117-183967313 -  3q27.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ALG3  -     3q27.1   [Description]    (hg38-Dec_2013)
EnsemblALG3 - 3q27.1 [CytoView hg19]  ALG3 - 3q27.1 [CytoView hg38]
Mapping of homologs : NCBIALG3 [Mapview hg19]  ALG3 [Mapview hg38]
OMIM601110   608750   
Gene and transcription
Genbank (Entrez)AK289361 AK297701 AK299575 AW297350 BC002839
RefSeq transcript (Entrez)NM_001006940 NM_001006941 NM_005787
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_008924 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)ALG3
Cluster EST : UnigeneHs.478481 [ NCBI ]
CGAP (NCI)Hs.478481
Alternative Splicing GalleryENSG00000214160
Gene ExpressionALG3 [ NCBI-GEO ]   ALG3 [ EBI - ARRAY_EXPRESS ]   ALG3 [ SEEK ]   ALG3 [ MEM ]
Gene Expression Viewer (FireBrowse)ALG3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10195
GTEX Portal (Tissue expression)ALG3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92685   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92685  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92685
Splice isoforms : SwissVarQ92685
Catalytic activity : Enzyme2.4.1.258 [ Enzyme-Expasy ]   2.4.1.2582.4.1.258 [ IntEnz-EBI ]   2.4.1.258 [ BRENDA ]   2.4.1.258 [ KEGG ]   
PhosPhoSitePlusQ92685
Domains : Interpro (EBI)Glycosyltransferase_ALG3   
Domain families : Pfam (Sanger)ALG3 (PF05208)   
Domain families : Pfam (NCBI)pfam05208   
Conserved Domain (NCBI)ALG3
DMDM Disease mutations10195
Blocks (Seattle)ALG3
SuperfamilyQ92685
Human Protein AtlasENSG00000214160
Peptide AtlasQ92685
HPRD03067
IPIIPI00178700   IPI00790912   IPI00927184   IPI00926684   IPI00926477   IPI00926233   IPI00926039   IPI00925785   
Protein Interaction databases
DIP (DOE-UCLA)Q92685
IntAct (EBI)Q92685
FunCoupENSG00000214160
BioGRIDALG3
STRING (EMBL)ALG3
ZODIACALG3
Ontologies - Pathways
QuickGOQ92685
Ontology : AmiGOalpha-1,3-mannosyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  protein glycosylation  dolichol-linked oligosaccharide biosynthetic process  integral component of membrane  protein N-linked glycosylation via asparagine  post-translational protein modification  cellular protein metabolic process  dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity  mannosylation  mannosylation  
Ontology : EGO-EBIalpha-1,3-mannosyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  protein glycosylation  dolichol-linked oligosaccharide biosynthetic process  integral component of membrane  protein N-linked glycosylation via asparagine  post-translational protein modification  cellular protein metabolic process  dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity  mannosylation  mannosylation  
Pathways : KEGGN-Glycan biosynthesis   
NDEx NetworkALG3
Atlas of Cancer Signalling NetworkALG3
Wikipedia pathwaysALG3
Orthology - Evolution
OrthoDB10195
GeneTree (enSembl)ENSG00000214160
Phylogenetic Trees/Animal Genes : TreeFamALG3
HOVERGENQ92685
HOGENOMQ92685
Homologs : HomoloGeneALG3
Homology/Alignments : Family Browser (UCSC)ALG3
Gene fusions - Rearrangements
Fusion: TCGAACTL6A ALG3
Fusion: TCGAB3GNT5 ALG3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALG3
dbVarALG3
ClinVarALG3
1000_GenomesALG3 
Exome Variant ServerALG3
ExAC (Exome Aggregation Consortium)ALG3 (select the gene name)
Genetic variants : HAPMAP10195
Genomic Variants (DGV)ALG3 [DGVbeta]
DECIPHER (Syndromes)3:183960117-183967313  ENSG00000214160
CONAN: Copy Number AnalysisALG3 
Mutations
ICGC Data PortalALG3 
TCGA Data PortalALG3 
Broad Tumor PortalALG3
OASIS PortalALG3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALG3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALG3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ALG3
DgiDB (Drug Gene Interaction Database)ALG3
DoCM (Curated mutations)ALG3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALG3 (select a term)
intoGenALG3
Cancer3DALG3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601110    608750   
Orphanet11347   
MedgenALG3
Genetic Testing Registry ALG3
NextProtQ92685 [Medical]
TSGene10195
GENETestsALG3
Huge Navigator ALG3 [HugePedia]
snp3D : Map Gene to Disease10195
BioCentury BCIQALG3
ClinGenALG3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10195
Chemical/Pharm GKB GenePA134897460
Clinical trialALG3
Miscellaneous
canSAR (ICR)ALG3 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALG3
EVEXALG3
GoPubMedALG3
iHOPALG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:06 CET 2017

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