| Nomenclature | | HGNC (Hugo) | ALKBH8 25189 |
| Entrez_Gene (NCBI) | ALKBH8 91801 alkB, alkylation repair homolog 8 (E. coli) |
| Cards | | GeneCards (Weizmann) | ALKBH8 |
| Ensembl (Hinxton) | ENSG00000137760 [Gene_View] chr11:107373453-107436461 [Contig_View] ALKBH8 [Vega] |
| AceView (NCBI) | ALKBH8 |
| Genatlas (Paris) | ALKBH8 |
| SOURCE (Stanford) | NM_138775 |
| Genomic and cartography | | GoldenPath (UCSC) | ALKBH8 - 11q22.3 chr11:107373453-107436461 - 11q22.3 [Description] (hg19-Feb_2009) |
| Ensembl | ALKBH8 - 11q22.3 [CytoView] |
| Mapping of homologs : NCBI | ALKBH8 [Mapview] |
| OMIM | 613306 |
| Gene and transcription |
| Genbank (Entrez) | AB218768 AF086489 AK095523 AK293603 AK298800 |
| RefSeq transcript (SRS) | NM_138775 |
| RefSeq transcript (Entrez) | NM_138775 |
| RefSeq genomic (SRS) | AC_000143 NC_000011 NC_018922 NT_033899 NW_001838042 NW_004078073 |
| RefSeq genomic (Entrez) | AC_000143 NC_000011 NC_018922 NT_033899 NW_001838042 NW_004078073 |
| Consensus coding sequences : CCDS (NCBI) | ALKBH8 |
| Cluster EST : Unigene | Hs.503763 [ SRS ] Hs.503763 [ NCBI ] |
| CGAP (NCI) | Hs.503763 |
| Alternative Splicing : Fast-db (Paris) | GSHG0006152 |
| Alternative Splicing Gallery | ENSG00000137760 |
| Gene Expression | ALKBH8 [ NCBI-GEO ] ALKBH8 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q96BT7 (SRS) Q96BT7 (Uniprot) |
| NextProt | Q96BT7 |
| With graphics : InterPro | Q96BT7 |
| Splice isoforms : SwissVar | Q96BT7(Swissvar) |
| Domaine pattern : Prosite (SRS) | FE2OG_OXY (PS51471) RRM (PS50102) |
| Domaine pattern : Prosite (Expaxy) | FE2OG_OXY (PS51471) RRM (PS50102) |
| Domains : Interpro (SRS) | AlkB_hom8_N Methyltransf_11 Nucleotide-bd_a/b_plait Oxoglu/Fe-dep_dioxygenase |
| Domains : Interpro (EBI) | AlkB_hom8_N Methyltransf_11 Nucleotide-bd_a/b_plait Oxoglu/Fe-dep_dioxygenase |
| Related proteins : CluSTr | Q96BT7 |
| Domain families : Pfam (SRS) | 2OG-FeII_Oxy_2 (PF13532) DUF1891 (PF09004) Methyltransf_11 (PF08241) |
| Domain families : Pfam (Sanger) | 2OG-FeII_Oxy_2 (PF13532) DUF1891 (PF09004) Methyltransf_11 (PF08241) |
| Domain families : Pfam (NCBI) | pfam13532 pfam09004 pfam08241 |
| DMDM | 91801 |
| Blocks (Seattle) | Q96BT7 |
| PDB (SRS) | 2CQ2 3THP 3THT |
| PDB (PDBSum) | 2CQ2 3THP 3THT |
| PDB (IMB) | 2CQ2 3THP 3THT |
| PDB (RSDB) | 2CQ2 3THP 3THT |
| Human Protein Atlas | ENSG00000137760 |
| HPRD | 14287 |
| IPI | IPI00154533 IPI00026191 IPI00873081 IPI00966763 IPI00973899 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q96BT7 |
| IntAct (EBI) | Q96BT7 |
| FunCoup | ENSG00000137760 |
| REACTOME | ALKBH8 |
| Protein Interaction Database | 91801 |
| BioGRID | ALKBH8 |
| InParanoid | Q96BT7 |
| Interologous Interaction database | Q96BT7 |
| IntegromeDB | ALKBH8 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | ALKBH8 |
| SNP (GeneSNP Utah) | ALKBH8 |
| SNP : HGBase | ALKBH8 |
| Genetic variants : HAPMAP | ALKBH8 |
| Somatic Mutations in Cancer : COSMIC | ALKBH8 |
| CONAN: Copy Number Analysis | ALKBH8 |
| Mutations and Diseases : HGMD | ALKBH8 |
| OMIM | 613306 |
| GENETests | 613306 |
| Disease Genetic Association | ALKBH8 |
| Huge Navigator |
ALKBH8 [HugePedia] ALKBH8 [HugeCancerGEM] |
| Genomic Variants | ALKBH8 ALKBH8 [DGVbeta] |
| snp3D : Map Gene to Disease | 91801 |
| General knowledge |
|---|
| Homologs : HomoloGene | ALKBH8 |
| Homology/Alignments : Family Browser (UCSC) | ALKBH8 |
| Phylogenetic Trees/Animal Genes : TreeFam | ALKBH8 |
| Catalytic activity : Enzyme | 1.14.11.- [ Enzyme-Expasy ] 1.14.11.- [ Enzyme-SRS ] 1.14.11.- [ IntEnz-EBI ] 1.14.11.- [ BRENDA ] 1.14.11.- [ KEGG ] |
| Chemical/Protein Interactions : CTD | 91801 |
| Chemical/Pharm GKB Gene | PA143485296 |
| Clinical trial | ALKBH8 |
| Cancer Resource (Charite) | ENSG00000137760 |
| Ontology : AmiGO | RNA binding protein binding nucleus nucleolus cytoplasm cytosol response to DNA damage stimulus microtubule cytoskeleton tRNA (uracil) methyltransferase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors tRNA methylation metal ion binding |
| Ontology : EGO-EBI | RNA binding protein binding nucleus nucleolus cytoplasm cytosol response to DNA damage stimulus microtubule cytoskeleton tRNA (uracil) methyltransferase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors tRNA methylation metal ion binding |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 6 Pubmed reference(s) in Entrez |
| PubGene | ALKBH8 |
| iHOP | ALKBH8 |
