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ALPK2 (alpha kinase 2)

Identity

Alias_symbol (synonym)HAK
Other alias
HGNC (Hugo) ALPK2
LocusID (NCBI) 115701
Atlas_Id 52830
Location 18q21.31  [Link to chromosome band 18q21]
Location_base_pair Starts at 58481250 and ends at 58628957 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ALPK2   20565
Cards
Entrez_Gene (NCBI)ALPK2  115701  alpha kinase 2
AliasesHAK
GeneCards (Weizmann)ALPK2
Ensembl hg19 (Hinxton)ENSG00000198796 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198796 [Gene_View]  chr18:58481250-58628957 [Contig_View]  ALPK2 [Vega]
ICGC DataPortalENSG00000198796
TCGA cBioPortalALPK2
AceView (NCBI)ALPK2
Genatlas (Paris)ALPK2
WikiGenes115701
SOURCE (Princeton)ALPK2
Genetics Home Reference (NIH)ALPK2
Genomic and cartography
GoldenPath hg38 (UCSC)ALPK2  -     chr18:58481250-58628957 -  18q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ALPK2  -     18q21.31   [Description]    (hg19-Feb_2009)
EnsemblALPK2 - 18q21.31 [CytoView hg19]  ALPK2 - 18q21.31 [CytoView hg38]
Mapping of homologs : NCBIALPK2 [Mapview hg19]  ALPK2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK092133 AK092194 AK125243 AL832018 AY044450
RefSeq transcript (Entrez)NM_052947
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ALPK2
Cluster EST : UnigeneHs.628152 [ NCBI ]
CGAP (NCI)Hs.628152
Alternative Splicing GalleryENSG00000198796
Gene ExpressionALPK2 [ NCBI-GEO ]   ALPK2 [ EBI - ARRAY_EXPRESS ]   ALPK2 [ SEEK ]   ALPK2 [ MEM ]
Gene Expression Viewer (FireBrowse)ALPK2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115701
GTEX Portal (Tissue expression)ALPK2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86TB3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86TB3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86TB3
Splice isoforms : SwissVarQ86TB3
Catalytic activity : Enzyme2.7.11.- [ Enzyme-Expasy ]   2.7.11.-2.7.11.- [ IntEnz-EBI ]   2.7.11.- [ BRENDA ]   2.7.11.- [ KEGG ]   
PhosPhoSitePlusQ86TB3
Domaine pattern : Prosite (Expaxy)ALPHA_KINASE (PS51158)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Kinase-like_dom    MHCK_EF2_kinase   
Domain families : Pfam (Sanger)Alpha_kinase (PF02816)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam02816    pfam07679   
Domain families : Smart (EMBL)Alpha_kinase (SM00811)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)ALPK2
DMDM Disease mutations115701
Blocks (Seattle)ALPK2
SuperfamilyQ86TB3
Human Protein AtlasENSG00000198796
Peptide AtlasQ86TB3
HPRD11019
IPIIPI00792557   IPI00646010   
Protein Interaction databases
DIP (DOE-UCLA)Q86TB3
IntAct (EBI)Q86TB3
FunCoupENSG00000198796
BioGRIDALPK2
STRING (EMBL)ALPK2
ZODIACALPK2
Ontologies - Pathways
QuickGOQ86TB3
Ontology : AmiGOprotein serine/threonine kinase activity  ATP binding  cytoplasm  protein phosphorylation  
Ontology : EGO-EBIprotein serine/threonine kinase activity  ATP binding  cytoplasm  protein phosphorylation  
NDEx NetworkALPK2
Atlas of Cancer Signalling NetworkALPK2
Wikipedia pathwaysALPK2
Orthology - Evolution
OrthoDB115701
GeneTree (enSembl)ENSG00000198796
Phylogenetic Trees/Animal Genes : TreeFamALPK2
HOVERGENQ86TB3
HOGENOMQ86TB3
Homologs : HomoloGeneALPK2
Homology/Alignments : Family Browser (UCSC)ALPK2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALPK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALPK2
dbVarALPK2
ClinVarALPK2
1000_GenomesALPK2 
Exome Variant ServerALPK2
ExAC (Exome Aggregation Consortium)ALPK2 (select the gene name)
Genetic variants : HAPMAP115701
Genomic Variants (DGV)ALPK2 [DGVbeta]
DECIPHERALPK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisALPK2 
Mutations
ICGC Data PortalALPK2 
TCGA Data PortalALPK2 
Broad Tumor PortalALPK2
OASIS PortalALPK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALPK2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALPK2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ALPK2
DgiDB (Drug Gene Interaction Database)ALPK2
DoCM (Curated mutations)ALPK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALPK2 (select a term)
intoGenALPK2
Cancer3DALPK2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenALPK2
Genetic Testing Registry ALPK2
NextProtQ86TB3 [Medical]
TSGene115701
GENETestsALPK2
Target ValidationALPK2
Huge Navigator ALPK2 [HugePedia]
snp3D : Map Gene to Disease115701
BioCentury BCIQALPK2
ClinGenALPK2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD115701
Chemical/Pharm GKB GenePA134916108
Clinical trialALPK2
Miscellaneous
canSAR (ICR)ALPK2 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALPK2
EVEXALPK2
GoPubMedALPK2
iHOPALPK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:54:51 CEST 2017

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