Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ALPK3 (alpha kinase 3)

Identity

Alias_symbol (synonym)MAK
KIAA1330
Midori
Other aliasMIDORI
HGNC (Hugo) ALPK3
LocusID (NCBI) 57538
Atlas_Id 60266
Location 15q25.3  [Link to chromosome band 15q25]
Location_base_pair Starts at 84816680 and ends at 84873482 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ALPK3   17574
Cards
Entrez_Gene (NCBI)ALPK3  57538  alpha kinase 3
AliasesMAK; MIDORI
GeneCards (Weizmann)ALPK3
Ensembl hg19 (Hinxton)ENSG00000136383 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136383 [Gene_View]  chr15:84816680-84873482 [Contig_View]  ALPK3 [Vega]
ICGC DataPortalENSG00000136383
TCGA cBioPortalALPK3
AceView (NCBI)ALPK3
Genatlas (Paris)ALPK3
WikiGenes57538
SOURCE (Princeton)ALPK3
Genetics Home Reference (NIH)ALPK3
Genomic and cartography
GoldenPath hg38 (UCSC)ALPK3  -     chr15:84816680-84873482 +  15q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ALPK3  -     15q25.3   [Description]    (hg19-Feb_2009)
EnsemblALPK3 - 15q25.3 [CytoView hg19]  ALPK3 - 15q25.3 [CytoView hg38]
Mapping of homologs : NCBIALPK3 [Mapview hg19]  ALPK3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB037751 AK022943 AK024829 AK026851 AK300484
RefSeq transcript (Entrez)NM_020778
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ALPK3
Cluster EST : UnigeneHs.459183 [ NCBI ]
CGAP (NCI)Hs.459183
Alternative Splicing GalleryENSG00000136383
Gene ExpressionALPK3 [ NCBI-GEO ]   ALPK3 [ EBI - ARRAY_EXPRESS ]   ALPK3 [ SEEK ]   ALPK3 [ MEM ]
Gene Expression Viewer (FireBrowse)ALPK3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57538
GTEX Portal (Tissue expression)ALPK3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96L96   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96L96  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96L96
Splice isoforms : SwissVarQ96L96
Catalytic activity : Enzyme2.7.11.- [ Enzyme-Expasy ]   2.7.11.-2.7.11.- [ IntEnz-EBI ]   2.7.11.- [ BRENDA ]   2.7.11.- [ KEGG ]   
PhosPhoSitePlusQ96L96
Domaine pattern : Prosite (Expaxy)ALPHA_KINASE (PS51158)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Kinase-like_dom    MHCK_EF2_kinase   
Domain families : Pfam (Sanger)Alpha_kinase (PF02816)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam02816    pfam07679   
Domain families : Smart (EMBL)Alpha_kinase (SM00811)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)ALPK3
DMDM Disease mutations57538
Blocks (Seattle)ALPK3
SuperfamilyQ96L96
Human Protein AtlasENSG00000136383
Peptide AtlasQ96L96
HPRD11365
IPIIPI00064935   
Protein Interaction databases
DIP (DOE-UCLA)Q96L96
IntAct (EBI)Q96L96
FunCoupENSG00000136383
BioGRIDALPK3
STRING (EMBL)ALPK3
ZODIACALPK3
Ontologies - Pathways
QuickGOQ96L96
Ontology : AmiGOprotein serine/threonine kinase activity  ATP binding  nucleus  protein phosphorylation  heart development  
Ontology : EGO-EBIprotein serine/threonine kinase activity  ATP binding  nucleus  protein phosphorylation  heart development  
NDEx NetworkALPK3
Atlas of Cancer Signalling NetworkALPK3
Wikipedia pathwaysALPK3
Orthology - Evolution
OrthoDB57538
GeneTree (enSembl)ENSG00000136383
Phylogenetic Trees/Animal Genes : TreeFamALPK3
HOVERGENQ96L96
HOGENOMQ96L96
Homologs : HomoloGeneALPK3
Homology/Alignments : Family Browser (UCSC)ALPK3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerALPK3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ALPK3
dbVarALPK3
ClinVarALPK3
1000_GenomesALPK3 
Exome Variant ServerALPK3
ExAC (Exome Aggregation Consortium)ALPK3 (select the gene name)
Genetic variants : HAPMAP57538
Genomic Variants (DGV)ALPK3 [DGVbeta]
DECIPHERALPK3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisALPK3 
Mutations
ICGC Data PortalALPK3 
TCGA Data PortalALPK3 
Broad Tumor PortalALPK3
OASIS PortalALPK3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICALPK3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDALPK3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ALPK3
DgiDB (Drug Gene Interaction Database)ALPK3
DoCM (Curated mutations)ALPK3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ALPK3 (select a term)
intoGenALPK3
Cancer3DALPK3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenALPK3
Genetic Testing Registry ALPK3
NextProtQ96L96 [Medical]
TSGene57538
GENETestsALPK3
Target ValidationALPK3
Huge Navigator ALPK3 [HugePedia]
snp3D : Map Gene to Disease57538
BioCentury BCIQALPK3
ClinGenALPK3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57538
Chemical/Pharm GKB GenePA134921552
Clinical trialALPK3
Miscellaneous
canSAR (ICR)ALPK3 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineALPK3
EVEXALPK3
GoPubMedALPK3
iHOPALPK3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:37:57 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.