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AMD1 (adenosylmethionine decarboxylase 1)

Identity

Alias_namesS-adenosylmethionine decarboxylase 1
Alias_symbol (synonym)SAMDC
Other aliasADOMETDC
AMD
HGNC (Hugo) AMD1
LocusID (NCBI) 262
Atlas_Id 626
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 110874784 and ends at 110895712 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AMD1 (6q21) / AMD1 (6q21)AMD1 (6q21) / ECHDC1 (6q22.33)AMD1 (6q21) / GAPDH (12p13.31)
AMD1 (6q21) / TNFAIP3 (6q23.3)NAA60 (16p13.3) / AMD1 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AMD1   457
Cards
Entrez_Gene (NCBI)AMD1  262  adenosylmethionine decarboxylase 1
AliasesADOMETDC; AMD; SAMDC
GeneCards (Weizmann)AMD1
Ensembl hg19 (Hinxton)ENSG00000123505 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123505 [Gene_View]  ENSG00000123505 [Sequence]  chr6:110874784-110895712 [Contig_View]  AMD1 [Vega]
ICGC DataPortalENSG00000123505
TCGA cBioPortalAMD1
AceView (NCBI)AMD1
Genatlas (Paris)AMD1
WikiGenes262
SOURCE (Princeton)AMD1
Genetics Home Reference (NIH)AMD1
Genomic and cartography
GoldenPath hg38 (UCSC)AMD1  -     chr6:110874784-110895712 +  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMD1  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblAMD1 - 6q21 [CytoView hg19]  AMD1 - 6q21 [CytoView hg38]
Mapping of homologs : NCBIAMD1 [Mapview hg19]  AMD1 [Mapview hg38]
OMIM180980   
Gene and transcription
Genbank (Entrez)AA808049 AJ420527 AJ420567 AK026205 AK125644
RefSeq transcript (Entrez)NM_001033059 NM_001287214 NM_001287215 NM_001287216 NM_001634
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AMD1
Cluster EST : UnigeneHs.159118 [ NCBI ]
CGAP (NCI)Hs.159118
Alternative Splicing GalleryENSG00000123505
Gene ExpressionAMD1 [ NCBI-GEO ]   AMD1 [ EBI - ARRAY_EXPRESS ]   AMD1 [ SEEK ]   AMD1 [ MEM ]
Gene Expression Viewer (FireBrowse)AMD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)262
GTEX Portal (Tissue expression)AMD1
Human Protein AtlasENSG00000123505-AMD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17707   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17707  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17707
Splice isoforms : SwissVarP17707
PhosPhoSitePlusP17707
Domaine pattern : Prosite (Expaxy)ADOMETDC (PS01336)   
Domains : Interpro (EBI)S-AdoMet_decarboxylase    S-AdoMet_deCO2ase_core    S-AdoMet_deCO2ase_CS   
Domain families : Pfam (Sanger)SAM_decarbox (PF01536)   
Domain families : Pfam (NCBI)pfam01536   
Conserved Domain (NCBI)AMD1
DMDM Disease mutations262
Blocks (Seattle)AMD1
PDB (SRS)1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
PDB (PDBSum)1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
PDB (IMB)1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
PDB (RSDB)1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
Structural Biology KnowledgeBase1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
SCOP (Structural Classification of Proteins)1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
CATH (Classification of proteins structures)1I72    1I79    1I7B    1I7C    1I7M    1JEN    1JL0    1MSV    3DZ2    3DZ3    3DZ4    3DZ5    3DZ6    3DZ7    3EP3    3EP4    3EP5    3EP6    3EP7    3EP8    3EP9    3EPA    3EPB    3H0V    3H0W   
SuperfamilyP17707
Human Protein Atlas [tissue]ENSG00000123505-AMD1 [tissue]
Peptide AtlasP17707
HPRD01622
IPIIPI00016708   IPI00843816   IPI00909054   IPI00940974   IPI01018943   
Protein Interaction databases
DIP (DOE-UCLA)P17707
IntAct (EBI)P17707
FunCoupENSG00000123505
BioGRIDAMD1
STRING (EMBL)AMD1
ZODIACAMD1
Ontologies - Pathways
QuickGOP17707
Ontology : AmiGOadenosylmethionine decarboxylase activity  adenosylmethionine decarboxylase activity  cytosol  cytosol  S-adenosylmethioninamine biosynthetic process  polyamine metabolic process  spermine biosynthetic process  spermidine biosynthetic process  putrescine binding  S-adenosylmethionine metabolic process  
Ontology : EGO-EBIadenosylmethionine decarboxylase activity  adenosylmethionine decarboxylase activity  cytosol  cytosol  S-adenosylmethioninamine biosynthetic process  polyamine metabolic process  spermine biosynthetic process  spermidine biosynthetic process  putrescine binding  S-adenosylmethionine metabolic process  
Pathways : KEGGCysteine and methionine metabolism    Arginine and proline metabolism   
NDEx NetworkAMD1
Atlas of Cancer Signalling NetworkAMD1
Wikipedia pathwaysAMD1
Orthology - Evolution
OrthoDB262
GeneTree (enSembl)ENSG00000123505
Phylogenetic Trees/Animal Genes : TreeFamAMD1
HOVERGENP17707
HOGENOMP17707
Homologs : HomoloGeneAMD1
Homology/Alignments : Family Browser (UCSC)AMD1
Gene fusions - Rearrangements
Fusion : QuiverAMD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMD1
dbVarAMD1
ClinVarAMD1
1000_GenomesAMD1 
Exome Variant ServerAMD1
ExAC (Exome Aggregation Consortium)ENSG00000123505
GNOMAD BrowserENSG00000123505
Varsome BrowserAMD1
Genetic variants : HAPMAP262
Genomic Variants (DGV)AMD1 [DGVbeta]
DECIPHERAMD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMD1 
Mutations
ICGC Data PortalAMD1 
TCGA Data PortalAMD1 
Broad Tumor PortalAMD1
OASIS PortalAMD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AMD1
DgiDB (Drug Gene Interaction Database)AMD1
DoCM (Curated mutations)AMD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMD1 (select a term)
intoGenAMD1
Cancer3DAMD1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180980   
Orphanet
DisGeNETAMD1
MedgenAMD1
Genetic Testing Registry AMD1
NextProtP17707 [Medical]
TSGene262
GENETestsAMD1
Target ValidationAMD1
Huge Navigator AMD1 [HugePedia]
snp3D : Map Gene to Disease262
BioCentury BCIQAMD1
ClinGenAMD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD262
Chemical/Pharm GKB GenePA24763
Clinical trialAMD1
Miscellaneous
canSAR (ICR)AMD1 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMD1
EVEXAMD1
GoPubMedAMD1
iHOPAMD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:08:50 CEST 2018

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