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AMH (anti-Mullerian hormone)

Identity

Alias_symbol (synonym)MIS
Other aliasMIF
HGNC (Hugo) AMH
LocusID (NCBI) 268
Atlas_Id 628
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 2249279 and ends at 2252073 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Kidney: Nephroblastoma (Wilms tumor)

External links

Nomenclature
HGNC (Hugo)AMH   464
Cards
Entrez_Gene (NCBI)AMH  268  anti-Mullerian hormone
AliasesMIF; MIS
GeneCards (Weizmann)AMH
Ensembl hg19 (Hinxton)ENSG00000104899 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104899 [Gene_View]  chr19:2249279-2252073 [Contig_View]  AMH [Vega]
ICGC DataPortalENSG00000104899
TCGA cBioPortalAMH
AceView (NCBI)AMH
Genatlas (Paris)AMH
WikiGenes268
SOURCE (Princeton)AMH
Genetics Home Reference (NIH)AMH
Genomic and cartography
GoldenPath hg38 (UCSC)AMH  -     chr19:2249279-2252073 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMH  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblAMH - 19p13.3 [CytoView hg19]  AMH - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIAMH [Mapview hg19]  AMH [Mapview hg38]
OMIM261550   600957   
Gene and transcription
Genbank (Entrez)AI791949 BC033218 BC049194
RefSeq transcript (Entrez)NM_000479
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AMH
Cluster EST : UnigeneHs.112432 [ NCBI ]
CGAP (NCI)Hs.112432
Alternative Splicing GalleryENSG00000104899
Gene ExpressionAMH [ NCBI-GEO ]   AMH [ EBI - ARRAY_EXPRESS ]   AMH [ SEEK ]   AMH [ MEM ]
Gene Expression Viewer (FireBrowse)AMH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)268
GTEX Portal (Tissue expression)AMH
Human Protein AtlasENSG00000104899-AMH [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP03971   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP03971  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP03971
Splice isoforms : SwissVarP03971
PhosPhoSitePlusP03971
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)AMH_N    Cystine-knot_cytokine    Muellerian-inhibiting_factor    TGF-b_C    TGFb_CS   
Domain families : Pfam (Sanger)AMH_N (PF04709)    TGF_beta (PF00019)   
Domain families : Pfam (NCBI)pfam04709    pfam00019   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)AMH
DMDM Disease mutations268
Blocks (Seattle)AMH
SuperfamilyP03971
Human Protein Atlas [tissue]ENSG00000104899-AMH [tissue]
Peptide AtlasP03971
HPRD02979
IPIIPI00008577   
Protein Interaction databases
DIP (DOE-UCLA)P03971
IntAct (EBI)P03971
FunCoupENSG00000104899
BioGRIDAMH
STRING (EMBL)AMH
ZODIACAMH
Ontologies - Pathways
QuickGOP03971
Ontology : AmiGOpreantral ovarian follicle growth  urogenital system development  Mullerian duct regression  Mullerian duct regression  receptor binding  transforming growth factor beta receptor binding  hormone activity  extracellular region  extracellular region  extracellular space  cell-cell signaling  gonadal mesoderm development  sex determination  sex differentiation  aging  growth factor activity  regulation of receptor activity  positive regulation of gene expression  response to organic cyclic compound  BMP signaling pathway  response to drug  positive regulation of NF-kappaB transcription factor activity  negative regulation of ovarian follicle development  
Ontology : EGO-EBIpreantral ovarian follicle growth  urogenital system development  Mullerian duct regression  Mullerian duct regression  receptor binding  transforming growth factor beta receptor binding  hormone activity  extracellular region  extracellular region  extracellular space  cell-cell signaling  gonadal mesoderm development  sex determination  sex differentiation  aging  growth factor activity  regulation of receptor activity  positive regulation of gene expression  response to organic cyclic compound  BMP signaling pathway  response to drug  positive regulation of NF-kappaB transcription factor activity  negative regulation of ovarian follicle development  
Pathways : KEGGCytokine-cytokine receptor interaction    TGF-beta signaling pathway   
NDEx NetworkAMH
Atlas of Cancer Signalling NetworkAMH
Wikipedia pathwaysAMH
Orthology - Evolution
OrthoDB268
GeneTree (enSembl)ENSG00000104899
Phylogenetic Trees/Animal Genes : TreeFamAMH
HOVERGENP03971
HOGENOMP03971
Homologs : HomoloGeneAMH
Homology/Alignments : Family Browser (UCSC)AMH
Gene fusions - Rearrangements
Fusion : QuiverAMH
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMH
dbVarAMH
ClinVarAMH
1000_GenomesAMH 
Exome Variant ServerAMH
ExAC (Exome Aggregation Consortium)ENSG00000104899
GNOMAD BrowserENSG00000104899
Genetic variants : HAPMAP268
Genomic Variants (DGV)AMH [DGVbeta]
DECIPHERAMH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMH 
Mutations
ICGC Data PortalAMH 
TCGA Data PortalAMH 
Broad Tumor PortalAMH
OASIS PortalAMH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch AMH
DgiDB (Drug Gene Interaction Database)AMH
DoCM (Curated mutations)AMH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMH (select a term)
intoGenAMH
Cancer3DAMH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM261550    600957   
Orphanet1553   
DisGeNETAMH
MedgenAMH
Genetic Testing Registry AMH
NextProtP03971 [Medical]
TSGene268
GENETestsAMH
Target ValidationAMH
Huge Navigator AMH [HugePedia]
snp3D : Map Gene to Disease268
BioCentury BCIQAMH
ClinGenAMH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD268
Chemical/Pharm GKB GenePA24769
Clinical trialAMH
Miscellaneous
canSAR (ICR)AMH (select the gene name)
Probes
Litterature
PubMed304 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMH
EVEXAMH
GoPubMedAMH
iHOPAMH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon May 14 11:29:48 CEST 2018
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