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AMOTL1 (angiomotin like 1)

Identity

Alias (NCBI)JEAP
HGNC (Hugo) AMOTL1
HGNC Alias symbJEAP
HGNC Alias namejunction-enriched and associated protein
LocusID (NCBI) 154810
Atlas_Id 52612
Location 11q21  [Link to chromosome band 11q21]
Location_base_pair Starts at 94768356 and ends at 94876748 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AMOTL1 (11q21) / CCDC88B (11q13.1)AMOTL1 (11q21) / PPIF (10q22.3)AMOTL1 (11q21) / SLCO2B1 (11q13.4)
MPPED2 (11p14.1) / AMOTL1 (11q21)PIR-FIGF (Xp22.2) / AMOTL1 (11q21)SMARCD2 (17q23.3) / AMOTL1 (11q21)
AMOTL1 11q21 / CCDC88B 11q13.1AMOTL1 11q21 / SLCO2B1 11q13.4MPPED2 11p14.1 / AMOTL1 11q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AMOTL1   17811
Cards
Entrez_Gene (NCBI)AMOTL1    angiomotin like 1
AliasesJEAP
GeneCards (Weizmann)AMOTL1
Ensembl hg19 (Hinxton)ENSG00000166025 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166025 [Gene_View]  ENSG00000166025 [Sequence]  chr11:94768356-94876748 [Contig_View]  AMOTL1 [Vega]
ICGC DataPortalENSG00000166025
TCGA cBioPortalAMOTL1
AceView (NCBI)AMOTL1
Genatlas (Paris)AMOTL1
SOURCE (Princeton)AMOTL1
Genetics Home Reference (NIH)AMOTL1
Genomic and cartography
GoldenPath hg38 (UCSC)AMOTL1  -     chr11:94768356-94876748 +  11q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMOTL1  -     11q21   [Description]    (hg19-Feb_2009)
GoldenPathAMOTL1 - 11q21 [CytoView hg19]  AMOTL1 - 11q21 [CytoView hg38]
ImmunoBaseENSG00000166025
Genome Data Viewer NCBIAMOTL1 [Mapview hg19]  
OMIM614657   
Gene and transcription
Genbank (Entrez)AF453742 AK024350 AK074084 AK093699 AL137281
RefSeq transcript (Entrez)NM_001301007 NM_130847
Consensus coding sequences : CCDS (NCBI)AMOTL1
Gene ExpressionAMOTL1 [ NCBI-GEO ]   AMOTL1 [ EBI - ARRAY_EXPRESS ]   AMOTL1 [ SEEK ]   AMOTL1 [ MEM ]
Gene Expression Viewer (FireBrowse)AMOTL1 [ Firebrowse - Broad ]
GenevisibleExpression of AMOTL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)154810
GTEX Portal (Tissue expression)AMOTL1
Human Protein AtlasENSG00000166025-AMOTL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IY63   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IY63  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IY63
PhosPhoSitePlusQ8IY63
Domains : Interpro (EBI)Angiomotin    Angiomotin_C   
Domain families : Pfam (Sanger)Angiomotin_C (PF12240)   
Domain families : Pfam (NCBI)pfam12240   
Conserved Domain (NCBI)AMOTL1
SuperfamilyQ8IY63
AlphaFold pdb e-kbQ8IY63   
Human Protein Atlas [tissue]ENSG00000166025-AMOTL1 [tissue]
HPRD12451
Protein Interaction databases
DIP (DOE-UCLA)Q8IY63
IntAct (EBI)Q8IY63
BioGRIDAMOTL1
STRING (EMBL)AMOTL1
ZODIACAMOTL1
Ontologies - Pathways
QuickGOQ8IY63
Ontology : AmiGOangiogenesis  establishment of cell polarity involved in ameboidal cell migration  protein binding  cytosol  plasma membrane  bicellular tight junction  bicellular tight junction  Wnt signaling pathway  actin cytoskeleton organization  regulation of cell migration  cytoplasmic vesicle  hippo signaling  hippo signaling  identical protein binding  
Ontology : EGO-EBIangiogenesis  establishment of cell polarity involved in ameboidal cell migration  protein binding  cytosol  plasma membrane  bicellular tight junction  bicellular tight junction  Wnt signaling pathway  actin cytoskeleton organization  regulation of cell migration  cytoplasmic vesicle  hippo signaling  hippo signaling  identical protein binding  
Pathways : KEGGTight junction   
NDEx NetworkAMOTL1
Atlas of Cancer Signalling NetworkAMOTL1
Wikipedia pathwaysAMOTL1
Orthology - Evolution
OrthoDB154810
GeneTree (enSembl)ENSG00000166025
Phylogenetic Trees/Animal Genes : TreeFamAMOTL1
Homologs : HomoloGeneAMOTL1
Homology/Alignments : Family Browser (UCSC)AMOTL1
Gene fusions - Rearrangements
Fusion : MitelmanAMOTL1/CCDC88B [11q21/11q13.1]  
Fusion : MitelmanAMOTL1/SLCO2B1 [11q21/11q13.4]  
Fusion : MitelmanMPPED2/AMOTL1 [11p14.1/11q21]  
Fusion : QuiverAMOTL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMOTL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMOTL1
dbVarAMOTL1
ClinVarAMOTL1
MonarchAMOTL1
1000_GenomesAMOTL1 
Exome Variant ServerAMOTL1
GNOMAD BrowserENSG00000166025
Varsome BrowserAMOTL1
ACMGAMOTL1 variants
VarityQ8IY63
Genomic Variants (DGV)AMOTL1 [DGVbeta]
DECIPHERAMOTL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMOTL1 
Mutations
ICGC Data PortalAMOTL1 
TCGA Data PortalAMOTL1 
Broad Tumor PortalAMOTL1
OASIS PortalAMOTL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMOTL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAMOTL1
Mutations and Diseases : HGMDAMOTL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAMOTL1
DgiDB (Drug Gene Interaction Database)AMOTL1
DoCM (Curated mutations)AMOTL1
CIViC (Clinical Interpretations of Variants in Cancer)AMOTL1
Cancer3DAMOTL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614657   
Orphanet
DisGeNETAMOTL1
MedgenAMOTL1
Genetic Testing Registry AMOTL1
NextProtQ8IY63 [Medical]
GENETestsAMOTL1
Target ValidationAMOTL1
Huge Navigator AMOTL1 [HugePedia]
ClinGenAMOTL1
Clinical trials, drugs, therapy
MyCancerGenomeAMOTL1
Protein Interactions : CTDAMOTL1
Pharm GKB GenePA24774
PharosQ8IY63
Clinical trialAMOTL1
Miscellaneous
canSAR (ICR)AMOTL1
HarmonizomeAMOTL1
DataMed IndexAMOTL1
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAMOTL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:16 CEST 2021

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