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AMOTL2 (angiomotin like 2)

Identity

Alias_symbol (synonym)LCCP
Other alias
HGNC (Hugo) AMOTL2
LocusID (NCBI) 51421
Atlas_Id 53853
Location 3q22.2  [Link to chromosome band 3q22]
Location_base_pair Starts at 134355345 and ends at 134375417 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AMOTL2 (3q22.2) / ADD3 (10q25.1)AMOTL2 (3q22.2) / AMOTL2 (3q22.2)AMOTL2 (3q22.2) / CAMSAP2 (1q32.1)
SFTPB (2p11.2) / AMOTL2 (3q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AMOTL2   17812
Cards
Entrez_Gene (NCBI)AMOTL2  51421  angiomotin like 2
AliasesLCCP
GeneCards (Weizmann)AMOTL2
Ensembl hg19 (Hinxton)ENSG00000114019 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114019 [Gene_View]  chr3:134355345-134375417 [Contig_View]  AMOTL2 [Vega]
ICGC DataPortalENSG00000114019
TCGA cBioPortalAMOTL2
AceView (NCBI)AMOTL2
Genatlas (Paris)AMOTL2
WikiGenes51421
SOURCE (Princeton)AMOTL2
Genetics Home Reference (NIH)AMOTL2
Genomic and cartography
GoldenPath hg38 (UCSC)AMOTL2  -     chr3:134355345-134375417 -  3q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMOTL2  -     3q22.2   [Description]    (hg19-Feb_2009)
EnsemblAMOTL2 - 3q22.2 [CytoView hg19]  AMOTL2 - 3q22.2 [CytoView hg38]
Mapping of homologs : NCBIAMOTL2 [Mapview hg19]  AMOTL2 [Mapview hg38]
OMIM614658   
Gene and transcription
Genbank (Entrez)AA056579 AB023206 AF175966 AI214560 AK001343
RefSeq transcript (Entrez)NM_001278683 NM_001278685 NM_016201
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AMOTL2
Cluster EST : UnigeneHs.713601 [ NCBI ]
CGAP (NCI)Hs.713601
Alternative Splicing GalleryENSG00000114019
Gene ExpressionAMOTL2 [ NCBI-GEO ]   AMOTL2 [ EBI - ARRAY_EXPRESS ]   AMOTL2 [ SEEK ]   AMOTL2 [ MEM ]
Gene Expression Viewer (FireBrowse)AMOTL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51421
GTEX Portal (Tissue expression)AMOTL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2J4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2J4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2J4
Splice isoforms : SwissVarQ9Y2J4
PhosPhoSitePlusQ9Y2J4
Domains : Interpro (EBI)Angiomotin    Angiomotin_C   
Domain families : Pfam (Sanger)Angiomotin_C (PF12240)   
Domain families : Pfam (NCBI)pfam12240   
Conserved Domain (NCBI)AMOTL2
DMDM Disease mutations51421
Blocks (Seattle)AMOTL2
SuperfamilyQ9Y2J4
Human Protein AtlasENSG00000114019
Peptide AtlasQ9Y2J4
HPRD16485
IPIIPI00478030   IPI00032236   IPI00942374   IPI00409571   IPI00963841   IPI00965721   IPI00967537   IPI00964679   IPI00964353   IPI00967316   IPI00964369   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2J4
IntAct (EBI)Q9Y2J4
FunCoupENSG00000114019
BioGRIDAMOTL2
STRING (EMBL)AMOTL2
ZODIACAMOTL2
Ontologies - Pathways
QuickGOQ9Y2J4
Ontology : AmiGOprotein binding  cytosol  bicellular tight junction  Wnt signaling pathway  apical plasma membrane  hippo signaling  identical protein binding  recycling endosome  
Ontology : EGO-EBIprotein binding  cytosol  bicellular tight junction  Wnt signaling pathway  apical plasma membrane  hippo signaling  identical protein binding  recycling endosome  
NDEx NetworkAMOTL2
Atlas of Cancer Signalling NetworkAMOTL2
Wikipedia pathwaysAMOTL2
Orthology - Evolution
OrthoDB51421
GeneTree (enSembl)ENSG00000114019
Phylogenetic Trees/Animal Genes : TreeFamAMOTL2
HOVERGENQ9Y2J4
HOGENOMQ9Y2J4
Homologs : HomoloGeneAMOTL2
Homology/Alignments : Family Browser (UCSC)AMOTL2
Gene fusions - Rearrangements
Fusion Cancer (Beijing)SFTPB [2p11.2]  -  AMOTL2 [3q22.2]  [FUSC003022]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMOTL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMOTL2
dbVarAMOTL2
ClinVarAMOTL2
1000_GenomesAMOTL2 
Exome Variant ServerAMOTL2
ExAC (Exome Aggregation Consortium)AMOTL2 (select the gene name)
Genetic variants : HAPMAP51421
Genomic Variants (DGV)AMOTL2 [DGVbeta]
DECIPHERAMOTL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMOTL2 
Mutations
ICGC Data PortalAMOTL2 
TCGA Data PortalAMOTL2 
Broad Tumor PortalAMOTL2
OASIS PortalAMOTL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMOTL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMOTL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AMOTL2
DgiDB (Drug Gene Interaction Database)AMOTL2
DoCM (Curated mutations)AMOTL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMOTL2 (select a term)
intoGenAMOTL2
Cancer3DAMOTL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614658   
Orphanet
MedgenAMOTL2
Genetic Testing Registry AMOTL2
NextProtQ9Y2J4 [Medical]
TSGene51421
GENETestsAMOTL2
Target ValidationAMOTL2
Huge Navigator AMOTL2 [HugePedia]
snp3D : Map Gene to Disease51421
BioCentury BCIQAMOTL2
ClinGenAMOTL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51421
Chemical/Pharm GKB GenePA24775
Clinical trialAMOTL2
Miscellaneous
canSAR (ICR)AMOTL2 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMOTL2
EVEXAMOTL2
GoPubMedAMOTL2
iHOPAMOTL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:23:37 CEST 2017

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