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AMY1A (amylase, alpha 1A (salivary))

Identity

Alias_namesAMY1
amylase
Other alias
HGNC (Hugo) AMY1A
LocusID (NCBI) 276
Atlas_Id 53776
Location 1p21.1  [Link to chromosome band 1p21]
Location_base_pair Starts at 103655519 and ends at 103664551 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AMY1A   474
Cards
Entrez_Gene (NCBI)AMY1A  276  amylase, alpha 1A (salivary)
AliasesAMY1
GeneCards (Weizmann)AMY1A
Ensembl hg19 (Hinxton)ENSG00000237763 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000237763 [Gene_View]  chr1:103655519-103664551 [Contig_View]  AMY1A [Vega]
ICGC DataPortalENSG00000237763
TCGA cBioPortalAMY1A
AceView (NCBI)AMY1A
Genatlas (Paris)AMY1A
WikiGenes276
SOURCE (Princeton)AMY1A
Genetics Home Reference (NIH)AMY1A
Genomic and cartography
GoldenPath hg38 (UCSC)AMY1A  -     chr1:103655519-103664551 +  1p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMY1A  -     1p21.1   [Description]    (hg19-Feb_2009)
EnsemblAMY1A - 1p21.1 [CytoView hg19]  AMY1A - 1p21.1 [CytoView hg38]
Mapping of homologs : NCBIAMY1A [Mapview hg19]  AMY1A [Mapview hg38]
OMIM104700   
Gene and transcription
Genbank (Entrez)AK292341 AK313275 BC063129 BC069347 BC069463
RefSeq transcript (Entrez)NM_001008221 NM_004038
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AMY1A
Cluster EST : UnigeneHs.655232 [ NCBI ]
CGAP (NCI)Hs.655232
Alternative Splicing GalleryENSG00000237763
Gene ExpressionAMY1A [ NCBI-GEO ]   AMY1A [ EBI - ARRAY_EXPRESS ]   AMY1A [ SEEK ]   AMY1A [ MEM ]
Gene Expression Viewer (FireBrowse)AMY1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)276
GTEX Portal (Tissue expression)AMY1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04745   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP04745  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04745
Splice isoforms : SwissVarP04745
PhosPhoSitePlusP04745
Domains : Interpro (EBI)A-amylase/branching_C    A-amylase_C    Alpha_amylase    Glyco_hydro_13_cat_dom    Glyco_hydro_b    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)Alpha-amylase (PF00128)    Alpha-amylase_C (PF02806)   
Domain families : Pfam (NCBI)pfam00128    pfam02806   
Domain families : Smart (EMBL)Aamy (SM00642)  Aamy_C (SM00632)  
Conserved Domain (NCBI)AMY1A
DMDM Disease mutations276
Blocks (Seattle)AMY1A
PDB (SRS)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
PDB (PDBSum)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
PDB (IMB)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
PDB (RSDB)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
Structural Biology KnowledgeBase1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
SCOP (Structural Classification of Proteins)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
CATH (Classification of proteins structures)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
SuperfamilyP04745
Human Protein AtlasENSG00000237763
Peptide AtlasP04745
HPRD00096
IPIIPI00641425   IPI00645326   
Protein Interaction databases
DIP (DOE-UCLA)P04745
IntAct (EBI)P04745
FunCoupENSG00000237763
BioGRIDAMY1A
STRING (EMBL)AMY1A
ZODIACAMY1A
Ontologies - Pathways
QuickGOP04745
Ontology : AmiGOalpha-amylase activity  protein binding  extracellular space  carbohydrate metabolic process  digestion  metal ion binding  extracellular exosome  
Ontology : EGO-EBIalpha-amylase activity  protein binding  extracellular space  carbohydrate metabolic process  digestion  metal ion binding  extracellular exosome  
Pathways : KEGGStarch and sucrose metabolism    Salivary secretion    Carbohydrate digestion and absorption   
NDEx NetworkAMY1A
Atlas of Cancer Signalling NetworkAMY1A
Wikipedia pathwaysAMY1A
Orthology - Evolution
OrthoDB276
GeneTree (enSembl)ENSG00000237763
Phylogenetic Trees/Animal Genes : TreeFamAMY1A
HOVERGENP04745
HOGENOMP04745
Homologs : HomoloGeneAMY1A
Homology/Alignments : Family Browser (UCSC)AMY1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMY1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMY1A
dbVarAMY1A
ClinVarAMY1A
1000_GenomesAMY1A 
Exome Variant ServerAMY1A
ExAC (Exome Aggregation Consortium)AMY1A (select the gene name)
Genetic variants : HAPMAP276
Genomic Variants (DGV)AMY1A [DGVbeta]
DECIPHERAMY1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMY1A 
Mutations
ICGC Data PortalAMY1A 
TCGA Data PortalAMY1A 
Broad Tumor PortalAMY1A
OASIS PortalAMY1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMY1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMY1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AMY1A
DgiDB (Drug Gene Interaction Database)AMY1A
DoCM (Curated mutations)AMY1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMY1A (select a term)
intoGenAMY1A
Cancer3DAMY1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104700   
Orphanet
MedgenAMY1A
Genetic Testing Registry AMY1A
NextProtP04745 [Medical]
TSGene276
GENETestsAMY1A
Target ValidationAMY1A
Huge Navigator AMY1A [HugePedia]
snp3D : Map Gene to Disease276
BioCentury BCIQAMY1A
ClinGenAMY1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD276
Chemical/Pharm GKB GenePA24781
Clinical trialAMY1A
Miscellaneous
canSAR (ICR)AMY1A (select the gene name)
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMY1A
EVEXAMY1A
GoPubMedAMY1A
iHOPAMY1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:54:55 CEST 2017

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