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AMY1B (amylase, alpha 1B (salivary))

Identity

Alias_namesAMY1
amylase, alpha 1B; salivary
Other alias
HGNC (Hugo) AMY1B
LocusID (NCBI) 277
Atlas_Id 60281
Location 1p21.1  [Link to chromosome band 1p21]
Location_base_pair Starts at 104198325 and ends at 104207172 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AMY1B   475
Cards
Entrez_Gene (NCBI)AMY1B  277  amylase, alpha 1B (salivary)
AliasesAMY1
GeneCards (Weizmann)AMY1B
Ensembl hg19 (Hinxton)ENSG00000174876 [Gene_View]  chr1:104198325-104207172 [Contig_View]  AMY1B [Vega]
Ensembl hg38 (Hinxton)ENSG00000174876 [Gene_View]  chr1:104198325-104207172 [Contig_View]  AMY1B [Vega]
ICGC DataPortalENSG00000174876
TCGA cBioPortalAMY1B
AceView (NCBI)AMY1B
Genatlas (Paris)AMY1B
WikiGenes277
SOURCE (Princeton)AMY1B
Genetics Home Reference (NIH)AMY1B
Genomic and cartography
GoldenPath hg19 (UCSC)AMY1B  -     chr1:104198325-104207172 +  1p21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AMY1B  -     1p21.1   [Description]    (hg38-Dec_2013)
EnsemblAMY1B - 1p21.1 [CytoView hg19]  AMY1B - 1p21.1 [CytoView hg38]
Mapping of homologs : NCBIAMY1B [Mapview hg19]  AMY1B [Mapview hg38]
OMIM104701   
Gene and transcription
Genbank (Entrez)AI627716 AK292341 AK313275 BC063129 BC069347
RefSeq transcript (Entrez)NM_001008218
RefSeq genomic (Entrez)NC_000001 NT_032977
Consensus coding sequences : CCDS (NCBI)AMY1B
Cluster EST : UnigeneHs.662103 [ NCBI ]
CGAP (NCI)Hs.662103
Alternative Splicing GalleryENSG00000174876
Gene ExpressionAMY1B [ NCBI-GEO ]   AMY1B [ EBI - ARRAY_EXPRESS ]   AMY1B [ SEEK ]   AMY1B [ MEM ]
Gene Expression Viewer (FireBrowse)AMY1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)277
GTEX Portal (Tissue expression)AMY1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04745   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP04745  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04745
Splice isoforms : SwissVarP04745
Catalytic activity : Enzyme3.2.1.1 [ Enzyme-Expasy ]   3.2.1.13.2.1.1 [ IntEnz-EBI ]   3.2.1.1 [ BRENDA ]   3.2.1.1 [ KEGG ]   
PhosPhoSitePlusP04745
Domains : Interpro (EBI)A-amylase_b_C    Alpha_amylase    Glyco_hydro_13    Glyco_hydro_13_b    Glyco_hydro_13_cat_dom    Glyco_hydro_13_sub_cat_dom    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)Alpha-amylase (PF00128)    Alpha-amylase_C (PF02806)   
Domain families : Pfam (NCBI)pfam00128    pfam02806   
Domain families : Smart (EMBL)Aamy (SM00642)  Aamy_C (SM00632)  
Conserved Domain (NCBI)AMY1B
DMDM Disease mutations277
Blocks (Seattle)AMY1B
PDB (SRS)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
PDB (PDBSum)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
PDB (IMB)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
PDB (RSDB)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
Structural Biology KnowledgeBase1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
SCOP (Structural Classification of Proteins)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
CATH (Classification of proteins structures)1C8Q    1JXJ    1JXK    1MFU    1MFV    1NM9    1Q4N    1SMD    1XV8    1Z32    3BLK    3BLP    3DHP   
SuperfamilyP04745
Human Protein AtlasENSG00000174876
Peptide AtlasP04745
HPRD18510
Protein Interaction databases
DIP (DOE-UCLA)P04745
IntAct (EBI)P04745
FunCoupENSG00000174876
BioGRIDAMY1B
STRING (EMBL)AMY1B
ZODIACAMY1B
Ontologies - Pathways
QuickGOP04745
Ontology : AmiGOalpha-amylase activity  protein binding  extracellular space  carbohydrate metabolic process  digestion  metal ion binding  extracellular exosome  
Ontology : EGO-EBIalpha-amylase activity  protein binding  extracellular space  carbohydrate metabolic process  digestion  metal ion binding  extracellular exosome  
Pathways : KEGGStarch and sucrose metabolism    Salivary secretion    Carbohydrate digestion and absorption   
NDEx NetworkAMY1B
Atlas of Cancer Signalling NetworkAMY1B
Wikipedia pathwaysAMY1B
Orthology - Evolution
OrthoDB277
GeneTree (enSembl)ENSG00000174876
Phylogenetic Trees/Animal Genes : TreeFamAMY1B
HOVERGENP04745
HOGENOMP04745
Homologs : HomoloGeneAMY1B
Homology/Alignments : Family Browser (UCSC)AMY1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMY1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMY1B
dbVarAMY1B
ClinVarAMY1B
1000_GenomesAMY1B 
Exome Variant ServerAMY1B
ExAC (Exome Aggregation Consortium)AMY1B (select the gene name)
Genetic variants : HAPMAP277
Genomic Variants (DGV)AMY1B [DGVbeta]
DECIPHER (Syndromes)1:104198325-104207172  ENSG00000174876
CONAN: Copy Number AnalysisAMY1B 
Mutations
ICGC Data PortalAMY1B 
TCGA Data PortalAMY1B 
Broad Tumor PortalAMY1B
OASIS PortalAMY1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMY1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMY1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AMY1B
DgiDB (Drug Gene Interaction Database)AMY1B
DoCM (Curated mutations)AMY1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMY1B (select a term)
intoGenAMY1B
Cancer3DAMY1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104701   
Orphanet
MedgenAMY1B
Genetic Testing Registry AMY1B
NextProtP04745 [Medical]
TSGene277
GENETestsAMY1B
Huge Navigator AMY1B [HugePedia]
snp3D : Map Gene to Disease277
BioCentury BCIQAMY1B
ClinGenAMY1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD277
Chemical/Pharm GKB GenePA24782
Clinical trialAMY1B
Miscellaneous
canSAR (ICR)AMY1B (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMY1B
EVEXAMY1B
GoPubMedAMY1B
iHOPAMY1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:12 CET 2017

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