AMY2A (amylase alpha 2A)

2010-08-01  

Identity

HGNC
LOCATION
1p21.1
LOCUSID
ALIAS
AMY2,PA

Other Information

Locus ID:

NCBI: 279
MIM: 104650
HGNC: 477
Ensembl: ENSG00000243480

Variants:

dbSNP: 279
ClinVar: 279
TCGA: ENSG00000243480
COSMIC: AMY2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000243480ENST00000414303P04746
ENSG00000243480ENST00000423678H7BZQ8
ENSG00000243480ENST00000622339P04746

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500

Pathways

PathwaySourceExternal ID
Starch and sucrose metabolismKEGGko00500
Starch and sucrose metabolismKEGGhsa00500
Metabolic pathwaysKEGGhsa01100
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Carbohydrate digestion and absorptionKEGGko04973
Carbohydrate digestion and absorptionKEGGhsa04973
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Digestion of dietary carbohydrateREACTOMER-HSA-189085

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
327182192021In silico assessment of potential leads identified from Bauhinia rufescens Lam. as α-glucosidase and α-amylase inhibitors.4
327182192021In silico assessment of potential leads identified from Bauhinia rufescens Lam. as α-glucosidase and α-amylase inhibitors.4
323145322020Association of AMY1A/AMY2A copy numbers and AMY1/AMY2 serum enzymatic activity with obesity in Mexican children.8
323145322020Association of AMY1A/AMY2A copy numbers and AMY1/AMY2 serum enzymatic activity with obesity in Mexican children.8
286593462017Starch Digestion-Related Amylase Genetic Variant Affects 2-Year Changes in Adiposity in Response to Weight-Loss Diets: The POUNDS Lost Trial.13
286593462017Starch Digestion-Related Amylase Genetic Variant Affects 2-Year Changes in Adiposity in Response to Weight-Loss Diets: The POUNDS Lost Trial.13
264957782016Relationships Between Fasting Serum Amylase and Ghrelin or Peptide YY3-36 Levels in Healthy Men.0
264957782016Relationships Between Fasting Serum Amylase and Ghrelin or Peptide YY3-36 Levels in Healthy Men.0
263350112015Role of Amylase-α2A Autoantibodies in the Diagnosis of Autoimmune Pancreatitis.8
263350112015Role of Amylase-α2A Autoantibodies in the Diagnosis of Autoimmune Pancreatitis.8
225845802012Functional regulation of sugar assimilation by N-glycan-specific interaction of pancreatic α-amylase with glycoproteins of duodenal brush border membrane.0
225845802012Functional regulation of sugar assimilation by N-glycan-specific interaction of pancreatic α-amylase with glycoproteins of duodenal brush border membrane.0
213663352011Chloride regulation of enzyme turnover: application to the role of chloride in photosystem II.9
213663352011Chloride regulation of enzyme turnover: application to the role of chloride in photosystem II.9
204287662010AMY2A: a possible tumor-suppressor gene of 1p21.1 loss in gastric carcinoma.6

Citation

Dessen P

AMY2A (amylase alpha 2A)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51645/amy2a